Olivier Elemento

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Olivier Elemento

Olivier Elemento

@ElementoLab

Director, Englander Institute for Precision Medicine @WCMenglanderIPM, Associate Director @wcmc_ctsc & ICB, Co-Founder @volastratx & @onethreebiotech

New York city Beigetreten Ocak 2012
945 Folgt6.2K Follower
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Hugo Aerts
Hugo Aerts@HugoAerts·
Big news: the thymus may be critical for adult health What if we missed something fundamental about the immune system? In two back-to-back papers in Nature, we show thymic health (AI on 30,000+ CT scans) links to longevity, disease risk & immunotherapy outcomes.
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Aaron Ring
Aaron Ring@aaronmring·
How specific are therapeutic monoclonal antibodies, really? In our new paper, @Yile_Dai led a collaboration with Adimab to profile 174 FDA-approved and clinical-stage mAbs against 6,172 human extracellular proteins. What we found surprised us.🧵 sciencedirect.com/science/articl…
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Lech Mazur
Lech Mazur@LechMazur·
New! LLM Thematic Generalization Benchmark V2! Models see 3 examples, 3 misleading anti-examples and 8 candidates with exactly 1 hidden correct answer. The theme is hidden. Can they infer the narrow latent rule instead of falling for the broader pattern?
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Mohammed AlQuraishi
Mohammed AlQuraishi@MoAlQuraishi·
New OpenFold3 preview out! (OF3p2) It closes the gap to AlphaFold3 for most modalities. Most critically, we're releasing everything, including training sets & configs, making OF3p2 the only current AF3-based model that is functionally trainable & reproducible from scratch🧵1/9
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Dr. Bishoy M. Faltas
Dr. Bishoy M. Faltas@FaltasLab·
Very grateful that our paper: The interplay between mutagenesis and extrachromosomal DNA shapes urothelial cancer evolution received the 2026 EAU Best Paper on Fundamental Research Award. @Uroweb nature.com/articles/s4158… I will be at #EAU26 in London and look forward to seeing friends and colleagues. If you want to talk science, #BladderCancer, or cancer evolution, let's connect. #TeamScience
Dr. Bishoy M. Faltas tweet mediaDr. Bishoy M. Faltas tweet media
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Georgia Channing
Georgia Channing@cgeorgiaw·
💊💊💊 @Ginkgo just dropped GDPx4 💊💊💊 29.9 MILLION rows of DRUG-seq data, perfect for benchmarking + large-scale perturbation modeling critical for anyone who can't afford their own high-throughput lab a little more in 🧵
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Patrick Hsu
Patrick Hsu@pdhsu·
Evo 2, our fully open-source biological foundation model trained on trillions of DNA tokens spanning the entire tree of life, is out in @Nature today We & the scientific community have done a lot with this @arcinstitute @nvidia model in the last year! 🧵👇
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WCM Englander Institute for Precision Medicine
Join us two weeks from Thursday for an @WCMEnglanderIPM #PrecisionMedicine Research Conference featuring Research #Pathology Fellows Drs. Eda Nur Kozan and Jesus Delgado De La Mora from @WCMCPathology! #NRG1 #WGS #FusionCarcinoma #CancerResearch
WCM Englander Institute for Precision Medicine@WCMEnglanderIPM

Join us March 19th for an @WCMEnglanderIPM #PrecisionMedicine Research Conference featuring Research #Pathology Fellows Drs. Eda Nur Kozan and Jesus Delgado De La Mora from @WCMCPathology! #NRG1 #WGS #FusionCarcinoma #CancerResearch

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William Gibson
William Gibson@wgibson·
While a 20% overall response rate, is not the kind of thing that makes a big splash in NEJM, there's reason to be very excited about this. The "impossible" label on TP53 has been ripped off. This is just the first of what I think will be many p53-targeted compounds to come.
NEJM@NEJM

Original Article: Phase 1 Study of Rezatapopt, a p53 Reactivator, in TP53 Y220C–Mutated Tumors (PYNNACLE study) https://nej.md/3OIQC5P Science behind the Study: Restoring Function to a Variant of p53 in Solid Tumors https://nej.md/3N0pQW8 #Oncology #Genetics

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