xilingli

What is acetylcholine doing in our brain? Does it control attention? React to our senses? Predict the future? Help move our body? Something else, or all of the above? Our new preprint biorxiv.org/content/10.110… provides insights that may surprise you! 🧵👇

Really excited to have this study out in @ScienceAdvances ! Here we show how synapses elegantly tune inhibition of release to increased vesicle size and glutamate - through a Glutamate-Gated Chloride channel (ivermectin target)!👇science.org/doi/10.1126/sc…

How do two antiparallel synapses at reciprocal synapses achieve functional compartmentalization? To find out, we systematically examine the molecular players involved in the trans-synaptic protein interaction network at the reciprocal synapses in vivo. biorxiv.org/content/10.110…