Alexandr Sember

Our new preprint is out＠bioRxiv: biorxiv.org/content/10.110… @MasaAShimazoe et al. reveal that linker histone H1 acts as a liquid-like "glue" to organize chromatin in living cells. 🎉 Fantastic collab with @rcollepardo, Charlie Phillips, @janhuemar and others—huge thanks! 🙌 1/2

1/9 #science #biology Very pleased to announced that our accepted paper (@TJNear & Alex Dornburg) on the early evolution of acanthopterygian fishes is out in @journal_evo. doi.org/10.1093/evolut…

Top 5 advances in medicine this week (🧵) 1. Vitamin C modifies the amino acid, lysine, to form VitCyl-lysine This is a novel post-translational modification: it promotes immunity and (in mice!) boosts anti-PD1 immunotherapy to kill cancer Whether vitamin C can also boost immunotherapy in humans isn't yet clear, but trials are ongoing Study: cell.com/cell/abstract/…

Rusko zaútočilo na Ukrajinu a mělo by nést odpovědnost za způsobené škody.

Listen to the Finnish president—this is what a real leader sounds like, unlike the nonsense Trump says.

Marjorie Courtenay-Latimer was born #OTD in 1907. In 1938 she found a very unusual fish in a market - a coelacanth, thought to be #extinct. It was later named after her with the generic name of Latimeria. 📷#Sketch by Courtenay-Latimer in "Old four-legs"/ JLB Smith, publ. 1956

Our new review on how the #chromatin domain is formed in the cell is out @ Curr Opin Struct Biol.📄✨ We critically discuss the domain formation mechanism from a physical perspective, including #phase-separation and #condensation. 📥 Free-download link: authors.elsevier.com/a/1keGn,LqArXq…

I am thrilled to share our new review on holocentric chromosomes. It was a lot of fun to write it together with Ines Drinnenberg! Same but different: Centromere regulations in holocentric insects and plants sciencedirect.com/science/articl…

I am excited to share our new paper about #Balkan #Pelophylax #waterfrogs! A pattern of hybridisation and population genetic structure of two water frog species (Ranidae, Amphibia) in the southwestern Balkans onlinelibrary.wiley.com/doi/10.1111/zs…

We are witnessing a very sad moment in American history. The President of the United States is aligning himself with the dictator of Russia, Vladimir Putin, to undermine the independence of Ukraine and its democracy. Here are my thoughts:

Registration open to the 12th @RepeatExplorer Workshop (May 27-29), this year focusing on repeat annotation in genome assemblies ! repeatexplorer.org/?page_id=14

Genomics of cold adaptations in the Antarctic notothenioid fish radiation nature.com/articles/s4146… @NatureComms

Gene expression and epigenetic status do not change following chromosomal inversions generated by CRISPR/Cas Khosravi et al. @LeibnizIPK 📖 nph.onlinelibrary.wiley.com/doi/10.1111/np…

Centromere evolution isn't a sudden switch! Our study shows centromere transitions are a step-by-step process driven by a combination of drift and selection. Discover how the kinetochore interface shapes this gradual change in our new preprint doi.org/10.1101/2025.0…  🧵(1/8)

Excited to announce the selected symposia for #ESEB2025 in #Barcelona! 📣​ From the origins of life to climate change adaptation, these sessions showcase gender balance, theoretical & methodological insights, and more. 🧪🔬​ Find out more 👉 bit.ly/4ag46Ne

@WenJuanMa84 and I are organising a symposium "Evolution and regulation of sex chromosomes and sex determination" at the #smbe2025 @OfficialSMBE this summer in #Beijing with @TatianaGiraud6 as the invited speaker. We look forward to your abstracts (before Jan.31th) and see you!!

Two resources to learn bioinformatics yourself: 1. Path to a free self-taught education in Bioinformatics! github.com/ossu/bioinform… #bioinformatics

Scientific drawing is an important skill that used to be an integral part of a scientists training 📝 I use vectors for my drawings- here are 5 reasons why they are awesome (1/6 🧵)

Welcome to Australia

Nice one just before the year turns again: academic.oup.com/aob/advance-ar…