Francisco Lobos

The biggest hummingbird in the world is a new species. Now out in @PNASNews and 8 years in the making, here's how we figured it out with mini tracking devices, genomics, and a century and a half of museum specimens.👇 pnas.org/doi/10.1073/pn… 🧵1/

My primary PhD project with @francesarnold at @Caltech is out now in @nchembio! Here we show that the β-subunit of tryptophan synthase (TrpB) is a latent *tyrosine* synthase (TyrS), capable of regioselective and irreversible alkylation of phenols to tyrosines. Read more below:

In 1599 the church used a placebo controlled trial to test if a French girl was possessed by a demon. Holy objects and identical, non-blessed objects were shown to the girl. "She reacted similarly when exposed to both genuine and sham religious objects" journals.sagepub.com/doi/full/10.11…

Thread of surreal sculpture details 🧵 1. Water flowing over toes

I love seeing HTML only websites But this is a top designer's portfolio. made only using HTML.

Many people asked what was behind this cultural shift towards industry in academia. Decided to dig into the latest @NSF data on sources of R&D funding to find out. The answer is pretty shocking!

Predicting and improving complex beer flavor through machine learning | Nature Communications nature.com/articles/s4146…

Too Many Labs Run Like This Derek Lowe writes about ‘a principal investigator steamrolling his own grad students and postdocs, hiding key details and pressuring everyone to get papers out no matter what misgivings they might be feeling.’ science.org/content/blog-p…

I wrote this Format dialog back on a rainy Thursday morning at Microsoft in late 1994, I think it was. We were porting the bajillion lines of code from the Windows95 user interface over to NT, and Format was just one of those areas where WindowsNT was different enough from Windows95 that we had to come up with some custom UI. I got out a piece of paper and wrote down all the options and choices you could make with respect to formatting a disk, like filesystem, label, cluster size, compression, encryption, and so on. Then I busted out VC++2.0 and used the Resource Editor to lay out a simple vertical stack of all the choices you had to make, in the approximate order you had to make. It wasn't elegant, but it would do until the elegant UI arrived. That was some 30 years ago, and the dialog is still my temporary one from that Thursday morning, so be careful about checking in "temporary" solutions! I also had to decide how much "cluster slack" would be too much, and that wound up constraining the format size of a FAT volume to 32GB. That limit was also an arbitrary choice that morning, and one that has stuck with us as a permanent side effect. So remember... there are no "temporary" checkins :) Follow me for more random code musings!

I think P<0.0001 would have been ok.😂

Results of my n=1 study on potassium supplementation and weight loss. potassium-weight-loss.org

These 11 people tell Skynet why they love working for Cyberdyne Systems

R.I.P. scientific publishing and peer-review system. sciencedirect.com/science/articl… #AcademicTwitter #academic #academia #researchers #research #phd @PhDVoice @PhD_Genie

The question is does one tattoo the UMAP made by Seurat or Scanpy?

couldn’t agree more about the need for more computational biologists. More importantly, we must ensure they receive the recognition and support they deserve. Their work should never be dismissed as merely “just service”. Additionally, I’d like to remind everyone of the excellent paper titled ‘All Biology is Computational Biology’. 🧬 💻

this is so grim

🤖 So #ChatGPT wrote the first sentence of this @ElsevierConnect article. Any other parts of the article too? How come none of the coauthors, Editor-in-Chief, reviewers, typesetters noticed? How can this happen with regular peer-review? pubpeer.com/publications/C…

"In some labs". The entire culture of modern science fosters a dynamic where people who produce desired results are favored, regardless of the quality of the work or even research integrity. You can't avoid that just by joining a different lab.

Working on an article for two years only to be called "et al."