Medscape

Upon presentation to the emergency department (ED), the monocyte distribution width (MDW) derived from routine full blood examinations could effectively differentiate acute severe ulcerative colitis (UC) from bacterial enterocolitis. mdsc.pe/4rPEJZF

Stop treating the kidney in isolation ✋ Managing heart failure requires a "cardiorenal metabolic mindset." Dr. Sato explains why long-term kidney preservation is the ultimate key to heart health. Watch the full debate ➡️ x.com/i/broadcasts/1… #CKD #CME #ISNWCN

An analysis of prescribing decisions for nearly 30,000 patients found most clinicians did not order preventive medications for patients with elevated lipoprotein(a) (Lp[a]) levels who were at low risk for atherosclerotic cardiovascular disease (ASCVD). However, some clinicians did prescribe lipid-lowering therapy. In rare cases, patients received aspirin or a PCSK9 inhibitor, according to a multicenter retrospective cohort study of patients who were tested for Lp(a). mdsc.pe/4t2qnpW

A quick, outpatient nasal swab can detect early biological changes linked to Alzheimer’s disease (AD) years before cognitive or memory symptoms present. Sampling cells in the upper nasal cavity via a minimally invasive brush biopsy may be able to detect AD years before symptoms appear. Investigators analyzed brush biopsy samples from the olfactory cleft — the narrow upper region of the nasal cavity that houses the olfactory epithelium — and identified immune and neuronal changes that mirror those seen in the brains of people with AD. These signatures distinguished individuals with preclinical and clinical AD from healthy control individuals. mdsc.pe/4t2DwPJ

The mistaken belief that stress can cause cancer leads many affected individuals to blame themselves for their cancer. A new study may shed some light on why this misconception exists - tap the link to watch the full episode of Impact Factor: mdsc.pe/4uREyjc

CGM Sweet Talk With the Sugar Queens: CGM Truths and Trends x.com/i/broadcasts/1…

New content available — Review and interpret clinical trial developments on oral SERDs and integrate trial evidence into MBC care for ER‑positive/HER2‑negative patients. mdsc.pe/4kWBePn

𝐖𝐀𝐓𝐂𝐇 𝐋𝐈𝐕𝐄 𝐈𝐍 𝟏 𝐇𝐎𝐔𝐑! youtube.com/watch?v=Bk7glO… CGM Truths & Trends! From finger sticks and sensor placement to exercise, travel, and trend arrows, The Sugar Queens will share their best pearls to help you confidently show patients how to use CGM effectively.

We’re launching a curriculum focused on translating heart failure guidelines into practical, real-world clinical decision-making. Which parameter is essential for guiding heart failure therapy optimization?

About one third of primary care physicians (PCPs) surveyed by Medscape said more than 20% of their patients also need mental and/or behavioral health treatment. Eighty-four percent of them feel that PCPs must play an essential role in this care, due to high needs and a shortage of specialist providers. This infographic presents key findings from a new Medscape report on how PCPs are helping shoulder rising demand for this care in the US. To learn more, see the Medscape Primary Care and Mental Health Treatment Report 2026: mdsc.pe/4t9G52I

Which strategy is most critical for improving outcomes in transthyretin amyloid cardiomyopathy (ATTR-CM)?

The unhealthy lifestyle behaviors that may underlie the notorious “freshman 15,” — ie, weight gain that some students may experience in starting college, often persist well into adulthood and are linked to a greater likelihood of having increases in BMI levels in early adulthood compared with those who have healthy lifestyle habits early on, new research showed. mdsc.pe/487EYs2

An individual patient data meta-analysis of two randomized trials involving treatment-naive patients with early rheumatoid arthritis (RA) found that a hand-dominant joint involvement pattern was associated with a modestly better response to both conventional synthetic and biologic disease-modifying antirheumatic drugs (csDMARDs and bDMARDs, respectively), whereas a polyarticular joint involvement pattern predicted a worse response. mdsc.pe/47isTQx

Millions of physicians like Dr. Akua Ampadu trust Medscape globally. Now, with Medscape AI, that trusted expertise delivers fairness, accuracy, and transparency at scale. Try it by tapping the link: mdsc.pe/47ljg3w #paid

A 43-year-old woman presents with a dry cough that has persisted for 3 months, despite empiric treatment. What’s the diagnosis? Case by Dr Martín-Portugués: mdsc.pe/4rNN3JH

Long wait times for an appointment with a specialist and for treatment after the referral are putting lives at risk, experts say. mdsc.pe/4t6K93J

Managing reflux starts with understanding the "plumbing". Experts share why the "Rule of 3", standing upright for three hours after meals, is a game-changer for patient success. Watch the full discussion for more clinical pearls ➡️ x.com/i/broadcasts/1… #Gastro #CME

Researchers are rethinking how we study tuberculosis and the results are surprising. A new “breathing” lung-on-a-chip model, built with multiple human lung and immune cell types, mimics real respiration and reveals how TB behaves in its earliest stages. In a recent study, the chip not only recreated key features of infection but also showed how coordinated cell interactions may help limit disease—offering new insight into TB progression and potential treatment strategies: mdsc.pe/4sCMYtA

Join us LIVE for an AMA with @drjohnm as he dives into #ACC26 trial data and new guidelines. 🗓️ April 2nd ⏰ 12 PM ET 🔗 youtube.com/watch?v=GJpjfy… Got a burning question? Submit at our Medscape ACC Booth #227 by 3/29 or drop it in the comments 👇 #ACC #Cardiology

Tina Merritt, MD, is an allergist and immunologist at Allergy & Asthma Clinic of Northwest Arkansas in Bentonville, and one of the pioneers in the study of alpha-gal syndrome. Medscape spoke with her about the initial discovery of the tick-triggered allergy, the evolving understanding of its biological mechanism, and how to manage patients with the condition: mdsc.pe/3PY46v2