Anjoom Nikhat

Inheritable 'memory' genes drive #cancer drug tolerance, but their discovery in clinical samples is a major challenge. Our new theory, moving away from Luria-Delbruck, detects them from a *single* scRNA-seq dataset! With #ArchishmanRaju led by @suvranil_1 tinyurl.com/4pef8scy

Is it always possible to assign #GeneExpression #CellStates to #SingleCells? Or can biological noise set fundamental limits? In our new work, we show that #CircadianClock states *cannot* be assigned to single cells due to transcriptional noise! tinyurl.com/4uxdxw2k (1/8)

Can we combine inhibitors of the #circadian clock and lineage correlations to detect presence of cell cycle gating by the clock? Excited about our new manuscript from @NCBS_Bangalore, @NCBStheory showing how this might be possible! A short thread (1/6) tinyurl.com/46pub9rh

Very excited to propose a new idea in the context of epigenetic inheritance - "Diffusion Accessible Domains" or DADs, in the first manuscript from our new lab at @NCBS_Bangalore and @NCBStheory. A big shoutout to @Architex_97 for all the hard work! Thread to follow soon.