
Israeli scientists have developed a simple stool test that could spare millions of inflammatory bowel disease patients from repeated colonoscopies - invasive procedures used to monitor gut inflammation and treatment effectiveness.
The breakthrough, led by Hebrew University of Jerusalem researchers and published in Microbiome, found that human DNA shed into stool by immune cells provides a detailed, real-time picture of intestinal inflammation. The discovery turns what scientists previously dismissed as biological "noise" into a powerful diagnostic tool.
"For too long, the human DNA found in stool samples was treated as biological 'noise' that we filtered out," said Professor Moran Yassour. "Our findings show that this DNA contains valuable, unappreciated information, reflecting the immune system's activity in real time." @HebrewU

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