Bosch Lab

The posters were buzzing! ⚡️ So many great chats on PNS regeneration, MLC1, and Wolfram syndrome, incredible to see the interest in our work!

🚀 Our lab had a strong presence at #ESGCT × #SETGYC in Sevilla! Talk on ALS, posters on gene therapy for PNS regeneration, MLC1 & Wolfram syndrome, plus @MiguelChillonLab on SPG52, GNB1 & HEBE chimeric protein. Wrapped up with feria-style tapas & music! 🎶

Just out: a comprehensive review of gene therapies in ALS – covering neuroprotection, ASOs, RNAi, CRISPR etc.; includes tables summarizing preclinical & clinical data, discusses hurdles & latest trial outcomes. 🔗Read more: liebertpub.com/doi/full/10.11…

A recent study led by Dr Assumpció Bosch (@absochlab) shows the potential of gene therapy to restore motor capacity in an ultra-rare disease (MLC), even when treatment begins after symptom onset #articledeldia Read the article: cutt.ly/VraHlhU2 🧵👇

🔬🧬 Our latest paper has just been published in Molecular Therapy (@MolTherapy)! In this study, conducted at @INC_UAB @UABBarcelona , we developed an intravenous gene therapy for MLC, an ultrarare leukodystrophy. cell.com/molecular-ther…

Our PI participated in the 9th Annual Wolfram Syndrome Research Symposium where she gave a talk on our latest findings. Thank you to the Snow Foundation for organizing this impactful event. We appreciate the opportunity to engage with the community! 🔗 shorturl.at/yci0p

Last week at #ESGCT2024 was incredible! Our team, alongside the Gene Therapy for CNS lab, showcased our work with 3 posters on gene therapies for rare diseases: MLC, SPG52, and ALS. It's always exciting to contribute to the future of the field and connect with colleagues!

PhD student Rubén Guerrero Yagüe presented his poster at the ESACT 2024 conference in Edinburgh on the 24th of June. He showcased the results from his thesis project conducted in our lab and discussed the future steps needed to advance the research! #ESACT2024 #PhD #Research

We are excited to share that our group is taking part in this groundbreaking project!

📰 La spin-off de la @UABBarcelona, ANEW MEDICAL, ja cotitza al @Nasdaq! Aquesta fita permetrà avançar en les teràpies gèniques per a malalties com l’#Alzheimer i l’esclerosi lateral amiotròfica (#ELA), patentades per la #UAB i @icreacommunity. 🔗 tuit.cat/daaok

Assumpció Bosch presented the MLC results at @UlfUnited Family Conference this weekend. She showed the in-vivo results performed in our lab and highlighted the next steps needed to bring the therapy to the clinic!