Michal Linial

Our review on #StatisticalGenetics is now on #arXiv. We list & discuss major open problems in human trait genetics, touching on #GWAS, #PolygenicRiskScore, #heritability, #RareVariants, #epistasis and more. arxiv.org/abs/2108.06684

Our recent paper on the genetics of cancer risk is now published in Scientific Reports. A thread... 1/20 nature.com/articles/s4159…

@SagivShifman my students were very fast in sharing these message.. I would say it different.. (but the paper was sent the submitted the same day to a real journal...) tnx

When you cite the work done before it is likely that one of those authors will review your paper. The risk is that they might claim that your findings are less novel and it will be rejected. A common and wrong practice is just to ignore previous studies…

Body mass index and birth weight improve polygenic risk score for type 2 diabetes medrxiv.org/content/10.110… Combined PRS with early-life measurements and separately considering males and females improve the utility of T2D -PRS..

@ShaiCarmi @erlichya למעשה בישראל ישנה ירידה בתמותה בחגים הלאומים.. במיוחד בחגי תשרי..זה נכון ל 20 שנה האחרונות medrxiv.org/content/10.110…

@erlichya מעניין. זה גם בישראל? יש בארץ עלייה בתמותה סביב ראש השנה?

We introduce FABRIC cancer portal. A ranked catalog of gene selection in tumors over the human coding genome in biorxiv.org/content/10.110… . For a cancer-centric view on known and overlooked cancer genes, visit fabric-cancer.huji.ac.il.

Recessive effects in cancer predisposition exposed by genome-wide and proteome-wide association studies biorxiv.org/content/10.110… GWAS and PWAS reveal known and novel cancer-type regions with cancer predisposition signals, many of which display recessive heritability.

Recessive effects in cancer predisposition exposed by genome-wide and proteome-wide association studies. GWAS and PWAS reveal known and novel cancer-type regions with cancer predisposition signals, many of which display recessive heritability. biorxiv.org/content/10.110…

De novo STXBP1 mutation in a child with developmental delay and spasticity reveals a major structural alteration in… pubmed.ncbi.nlm.nih.gov/32815282/

BIRD: identifying cell doublets via biallelic expression from single cells academic.oup.com/bioinformatics…

bioRxiv viewer disq.us/t/3qjan1g On Spliceosome-associated miRNAs, breast cancer cells (MCF-10A, MCF-7, MDA-MB-231) and some overlooked nuclear targets.

PWAS: Proteome-Wide Association Study biorxiv.org/content/10.110…

Significantly Improved COVID-19 Outcomes in Countries with Higher BCG Vaccination Coverage: A @Preprints_org preprints.org/manuscript/202…

My article is featured on the @ResearchGate #COVID19 community page. Read it here: researchgate.net/publication/34…

Significantly Improved COVID-19 Outcomes in Countries with Higher BCG Vaccination Coverage: A Multivariable Analysis medrxiv.org/content/10.110…

Significantly Improved COVID-19 Outcomes in Countries with Higher BCG Vaccination Coverage: A Multivariable Analysis medrxiv.org/content/10.110…

The SARS-CoV-2 exerts a distinctive strategy for interacting with the ACE2 human receptor biorxiv.org/content/10.110…

The SARS-CoV-2 exerts a distinctive strategy for interacting with the ACE2 human receptor disq.us/t/3muq27v