No one

By David Altmejd

Our cat is so thirsty!

24 year old Craig McCracken, creator of The Powerpuff Girls (1995)

The president cancelling tv shows he doesn’t like & memeing about it on social media is a dystopian nightmare. 10 years, the very thought of this occurring would have been uncontroversially anti-american. MAGA has destroyed our country.

We now have a female Bryan Johnson. It’s Kate Tolo. She will become the most measured female in history. +$2 million of spend per year + Developing a female-specific protocol + Sharing everything for free To start, she will spend 3 months mapping her baseline. Men, in contrast, can get their baseline done in 1 or 2 weeks. + 3 months for baseline measurement + across 4 time points per cycle + doing the same thing every day + a dedicated full-time medical team For context on the extensiveness of measurement, during the past 5 years, we’ve collected 1.5 billion data points on my body. I suspect Kate will exceed that given technology has improved since I started. The goal is to create a repeatable waveform of hundreds of life-critical biomarkers. Once the baseline is acquired, she will begin interventions. We will try to answer practically useful questions and share all of the data + learnings for free. Can fertility be improved? + Should women cold plunge? + Can PMS symptoms be alleviated? + What should a female sauna protocol be? + Should dosage change throughout the month? + What keeps a cycle regular? + Does the body need more iron, magnesium, or protein at specific phases? + Should women fast? + Should recovery protocol change by phase? + What's the earliest detectable signal of perimenopause? + Can perimenopause be slowed? + How is cognitive load & mood affected? + Does stress impact men and women the same? Kate has suspected endometriosis. 10% of all women do. We will try to tackle this too. I am excited for all of the surprising things we will hopefully uncover. Unlike me, Kate does not have the innate desire to wake up at 4:30am and do six hours of longevity therapies. She’s the cofounder of Blueprint, building in the trenches with me since day one. She understands the game and how hard it is. In many ways, this is a sacrifice for her. She is a creative person, going from a life of freedom and spontaneity to a rigid protocol. Traditionally, RCTs have been viewed as the gold standard. But RCTs have underserved women. The FDA banned women from clinical trials for 16 years (1977 to 1993), and most "medicine for women" is still medicine tested in men. Demanding RCT-only evidence for women's health is demanding evidence that doesn't exist. There is not enough practical scientific literature for women to reference only RCTs. It leaves half the population without a path to know what to do. N=1 medicine is gaining ground and picking up where RCTs specifically fail. Individual science experiments give us signals that answer what to do on a day-to-day basis. This is even more important for women. If you’re new to Kate and my world, I want you to understand that we have your back. Our intentions are to be a sturdy, reliable force in your life. To care for your best interest as we’d care for our own. We want what’s best for you and our loyalty is to your existence. It’s pretty cool to be living in a time when we may be the first generation to not die. I’m not suggesting immortality, but lifespans so long that we stop thinking about lifespans. At the end of the day, the one thing we each care about more than anything else is one more breath. I’m proud of Kate for taking on this responsibility. It’s painful, exhausting and costly. The beginning of the world’s first n=2.

OH MY GOD ITS DOGTOBER 7TH ALL OVER AGAIN

ngl, is it pretty weird that twitch allows people like asmongold and hasan, but destiny is permabanned for being a transmed. like idk what to make of it, is it that they prefer anything, even the far-right over liberalism? or is transphobia preferable to being a transmed to them?

"The Wings" by artist Choi Xooang.

I think it’s sooo cute that men finally invented a way to call other men hot. “Mogged” just means he’s the hotter one. That’s really beautiful

The judge being a chad is hilarious

An early meme, first published in 1921

@mints_____ bitch ass

@Ne0Liber4lShill He did a movie stream yesterday that didn’t do too bad for the average Streamer lol

Serious question, what is James Drake going to do for content other than watching fishtank or interviewing people from the show? That is the only time he gets good views. #fishtanklive

ekrana çıkan kedileri gerçek sanıp pati atması BAYILDIM

Conspiracy theory guy who thinks "magic bullet theory" is about JFK dying from shoving a vibrator up his ass

Feel like I achieved gnosis by learning that Hitachi made the Dreamcast CPU