Ryan Clarke

"There is perhaps no stronger evidence of the [Trump] administration’s objectives to reduce the quality of the US scientific workforce than its treatment of the National Science Foundation’s flagship Graduate Research Fellowship Program," writes H. Holden Thorp in a new #ScienceEditorial. scim.ag/4coukAg

@grok @feisty_mom_wife @44NNNNNNNN @alex2yc @grok can you please provide stats on how many MAGA accounts versus Democrat accounts are foreign based

Yes, recent reports following X's brief country-of-origin feature rollout confirm that some Democrat-aligned accounts, such as 'Ron Smith' (Kenya) and 'Republicans against Trump' (Austria), are operated from abroad. Similar findings apply to MAGA accounts from Nigeria, India, and elsewhere.

Dude this is crazy

This will be absolutely devastating in the medical field. ~30% residents are international medical graduates & ~10k of 43k residency spots are filled by docs with H1-B visas. Previously the h-1B fee was <$5,000. No hospital will pay a $100k fee for a $55k resident salary.

David Baltimore (March 7, 1938 – September 6, 2025). His discovery of reverse transcriptase, along with Howard Temin and Satoshi Mizutani, illuminated the retrovirus life cycle, led to the discovery of viral oncogenesis mechanisms and antiviral RT inhibitors, and enabled technologies including RT-PCR, RNA-seq, and prime editing. nytimes.com/2025/09/07/sci…

@DBeardedGOAT @krassenstein Holy shit you are an idiot lol

@krassenstein There’s so many freaks now it’s hard to follow. Let’s be clear. Men need to use men’s restrooms and women need to use women’s restrooms. A man can’t be a woman and a woman can’t be a man.

This is so sad. Trans man Luca Strobel, uses women’s restroom and then is allegedly assaulted by bar owner and detained by police. I want some of you transphobes to explain to me how this is ok.

@_JasonCorso_ @NickelBagsArt @NIH THIS

@NickelBagsArt @NIH Oh my. Society profits from health discoveries. 🤦 BTW, companies, like SpaceX also charge massive amounts of indirects (on their $3.8B in federal contracts) to the tune of 100%

Last year, $9B of the $35B that the National Institutes of Health (NIH) granted for research was used for administrative overhead, what is known as “indirect costs.” Today, NIH lowered the maximum indirect cost rate research institutions can charge the government to 15%, above what many major foundations allow and much lower than the 60%+ that some institutions charge the government today. This change will save more than $4B a year effective immediately.

@bourbon_rox @DrJennyReese @NIH maybe they should also take away the medicines you rely on that came out of government funded academic laboratories

@DrJennyReese @NIH And if it’s a research institution, they could build them. The government doesn’t need to fund buildings at universities.

The story behind how Generation 3.0 proGuides were engineered. They enable efficient, multi-step, pre-programmed CRISPR activation of endogenous genes. biorxiv.org/content/10.110…

Thank you for the great article ⁦⁦@medcitynews⁩ medcitynews.com/2023/09/startu…

The pioneer of DNA assembly EcoRI + DNA ligase* = the first recombinant plasmid

Very excited to see our work on Cas9 conformational activation out in @Nature ! nature.com/articles/s4158… What started as a very poor crystal structure back in 2017 in the @MartinJinek lab, turned into a full blown cryoEM project during the pandemic.

Here's a bacterium on a diatom on an amphipod on a frog on a bump on the log in the hole in the bottom of the sea [source, read more: bit.ly/2F8fbBC]

Why cell therapy is so cool.

Thank you @tool for spending 1,227 minutes with me this year on @Spotify. You are my #1. #SpotifyWrapped open.spotify.com/artist/2yEwvVS…

Video of #SARSCoV2 infecting brain cells (gray blobs) with cell fusion, hijacking, and explosive release of copies for more invasions nytimes.com/2021/08/22/sci… @NYTScience @AndrewJacobsNYT by @aicher_sophie and @Delphine_Planas @institutpasteur @justsaysinrats @NikonSmallWorld

Our paper is officially out in the latest issue of @MolecularCell

Read the latest issue cell.com/molecular-cell…

Online Now: Sequential Activation of Guide RNAs to Enable Successive CRISPR-Cas9 Activities dlvr.it/RpYD1c

No words needed. That's what vaccines do.

Incredible work!