I'm really grateful to the organizers for giving me the chance to discuss my first paper on #MVIF. Thanks to everyone in the audience for your great questions and comments about my talk. See you next time!
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Annabel Klemets
48 posts
Annabel Klemets
@annabel_kls
PhD student in the @TartuMicrobiome group at @genomicstartu and @unitartu.
Tartu, Estonia Katılım Mart 2024
127 Takip Edilen17 Takipçiler
I am very thankful to my wonderful co-authors @Kkrigul, @oliveraasmets, and @org_elin, as well as to our outstanding endocrinologists, Dr. Ingrid Reppo and Dr. Vallo Volke. This work wouldn’t have happened without your support!
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Overall, the gut microbiome may play a crucial role in the action of semaglutide and empagliflozin and could potentially be a key factor in tailoring the clinical treatment of type 2 diabetes. 🧵 5/5
#semaglutide #ozempic #empagliflozin #microbiome
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Very happy to share the results of my first preprint from @TartuMicrobiome. We found how the gut microbiome can impact semaglutide and empagliflozin treatment for type 2 diabetes. 🧵 1/5
medrxiv.org/content/10.110…
#semaglutide #ozempic #empagliflozin #microbiome #MicrobiomeResearch
medRxiv@medrxivpreprint
Fecal microbiome predicts treatment response after the initiation of semaglutide or empagliflozin uptake medrxiv.org/cgi/content/sh… #medRxiv
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Annabel Klemets retweetledi
We are excited to share this new pre-print on the first Estonian gut MAG collection. 🦠
The paper showcases the diversity of bacteria in the Estonian population and their links to prevalent diseases
Kateryna Pantiukh 🇺🇦@KPantiukh
‼️🦠 Excited to share my very first preprint on new Estonian #Microbiome MAGs from @ESTbiobank! Discoveries include a new bacteria from #humangut linked to prevalent diseases. biorxiv.org/cgi/content/sh… A thread 🧵 #mag#EstMB#TartuMicrobiome#MicrobiomeResearch #PhDlife
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Annabel Klemets retweetledi
And this girl (me!) can officially defend her PhD! Vacation - is this you?!
Bjo:rn Schro:der@bo_schroeder
Fantastic news before the summer: Our work on how a history of #antibiotic usage affects #gutmicrobiota and #mucus function is now accepted for publication (stay tuned!)! Big congratulations @KKrigul, @rachelfeen and everyone involved! Previous preprint: biorxiv.org/content/10.110…
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Annabel Klemets retweetledi
Very glad to see the expansion of our Estonian delegation of behavioral genetics researchers from the usual 2 (me and @KailiRimfeld ) to whopping 7 at #BGA2024 this year! Lots of great science using @ESTbiobank data was presented 📊🧬🧠 I hope this trend will continue! 📈
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Annabel Klemets retweetledi
"While much of Europe is obsessing over this year’s European Football Championships, many Estonians — whose team didn’t qualify — are absorbed in their own genomes."
And they have pretty awesome genomes, I must say!
Read the full story by @ewencallaway:
nature.com/articles/d4158…
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Annabel Klemets retweetledi
More detailed characterization of the gut #microbiome #T2D
offers new mechanistic insights into T2D #diabetes #microbiota @NatureMedicine nature.com/articles/s4159…
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Annabel Klemets retweetledi
Real world data shows that among 25,824 older people with #T2D GLP-1RAs were associated with a significant decrease in the risk of #depression compared to DPP4i #T2D #ADA2024 diabetesjournals.org/diabetes/artic…
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Annabel Klemets retweetledi
These 2 drug classes work differently; both reduce cardiovascular mortality. There's been much speculation about combining GLP-1 + SGLT-2s. Data from a randomized trial in people w/ diabetes and kidney disease failed to show additivity beyond GLP-1
nature.com/articles/s4159…
@NatureMedicine @KatherineTuttl8
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Annabel Klemets retweetledi
#IHMC2024 in Rome starts tomorrow! Come and lets have a chat on the role of widely used hormonal contraceptives on the female gut microbiome. My poster is up on the 25th of June at 8.30 to 9.30. Poster nr 541.
Tartu_Microbiome@TartuMicrobiome
@org_elin 🧵 4/5 June 25: @KreeteLull presents poster on the effect of hormonal contraceptives on the gut microbiome (8.30 to 9:00, Room Q monitor 3) #tartumicrobiome #IHMC2024 #EstMB #contraceptives #metagenomics
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I am excited to share the results of my first PhD project! Join me at poster no. 441 and grab a sticker ✨ #IHMC2024
Tartu_Microbiome@TartuMicrobiome
@org_elin 🧵 5/5 June 25: @annabel_kls presents how semaglutide and gut microbiome impact each other (08:30 to 09:00, Room Q, Monitor 1) #tartumicrobiome #IHMC2024 #semaglutide #ozempic #microbiome
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Annabel Klemets retweetledi
You can’t miss our cute bacteria stickers! Visit our posters to collect one 🧵 1/5
June 24: @org_elin presents long-term consequences of drug usage on the gut microbiome (16:30 to 17:00, Room Q, Monitor 1)
#tartumicrobiome #IHMC2024 #EstMB #pharmacomicrobiomics
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Annabel Klemets retweetledi
60 000 🙌 Aidake siis nädalavahetusel vanaemal ja vanaisal ka portaal.geenidoonor.ee sisse logida! 💜
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Annabel Klemets retweetledi
As my PhD comes to an end, I want to acknowledge the methods books that have been instrumental in my journey. *Missing from the list is statistical rethinking
This book by Dale Barr has also been exceptionally helpful:
psyteachr.github.io/stat-models-v1/
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Annabel Klemets retweetledi
The new MGnifyR package has now support for the *TreeSummarizedExperiment* Bioconductor data container (by Huang et al. 2021), which is specifically designed to support multi-assay integration & analyses.
Leo Lahti@antagomir
MGnifyR - R interface to access open metagenome data from @emblebi @MGnifyDB is now available via @Bioconductor bioconductor.org/packages/relea…
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