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James Evans@evansrjames·1 Eyl

Out now on biorxiv! Excited to share our latest collaborative work investigating the earliest stages of Parkinson’s disease. biorxiv.org/content/10.110… Thanks to all the amazing co-authors Melissa Grant-Peters Joseph Beckwith Steven Lee Mina Ryten @LabGandhi

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bioRxiv Neuroscience@biorxiv_neursci·28 Ağu

Microglial activation and alpha-synuclein oligomers drive the early inflammatory phase of Parkinson's disease biorxiv.org/content/10.110… #biorxiv_neursci

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bioRxiv Cell Biology@biorxiv_cellbio·10 Nis

VP-CLEM-Kit: An accessible pipeline for visual proteomics using super resolution volume correlative light and electron microscopy ... biorxiv.org/content/10.110… #biorxiv_cellbio

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James Evans@evansrjames·9 Eki

Really exciting to be involved with this work! Congrats @EM_STP and team!

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James Evans@evansrjames·17 Tem

@maffeibenito @UniversityLeeds @ScienceLeeds Congratulations Benito!

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Benito Maffei@maffeibenito·17 Tem

Huge congratulations to all the authors! A collaboration across Leeds, Shijiazhuang and Cincinnati. Thanks to Professor Nikita Gamper and Dr Fred Jones for their supervision during my undergraduate project @UniversityLeeds @ScienceLeeds jci.org/articles/view/…

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Benito Maffei@maffeibenito·17 Tem

Insight into how sattelite glial cells mediate gabaergic tone across the DRG in the peripheral gating of #nociception #pain Very grateful to have a small part of my undergraduate thesis published! Look forward to seeing new developments in #chronicpain #therapeutics

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The Science of Parkinson's@ScienceofPD·28 Haz

New research suggests nonlysosomal roles for #Parkinsons-associated GBA1 & its highly homologous pseudogene GBAP1 "with implications for our understanding of the role of GBA1 in health & disease" - from @em_ka_gu et al; Concealment of GBA1 by GBAP1 science.org/doi/10.1126/sc…

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Christian Lambert@clambert112358·25 Haz

Exciting multiscale post-doc opportunity in #Parkinsons @WCHN_UCL & @TheCrick: Combining individual specific cell models @LabGandhi with longitudinal qMRI in the same person to define mechanisms of progression See link for details: ucl.ac.uk/work-at-ucl/se… @OHBM #OHBM2024

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Liz Tseng@Magdoll·18 Haz

Targeted @PacBio Iso-Seq identifies novel SNCA transcripts in human dopaminergic neurons, many with novel UTRs and encodes novel peptides, and used to design antisense oligonucleotides (ASO) leading to the effective reversal of Parkinson's Disease (PD) pathology biorxiv.org/content/10.110…

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James Evans@evansrjames·3 Haz

@mgrantpeters Congratulations, Melissa! 🥳

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Louise Huuki-Myers@lahuuki

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Melissa Grant-Peters@mgrantpeters·3 Haz

Delighted to see this published! It has been a pleasure to work with such a talented group of people.

New in @sciencemagazine: our work from @LieberInstitute #spatialDLPFC applies #snRNAseq and #Visium spatial transcriptomic in the DLPFC to better understand anatomical structure and cellular populations in the human brain #PsychENCODE doi.org/10.1126/scienc…

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Flora Carr@floracarr_·19 Nis

Very surreal to see THE TOWER pictured inside Barnes & Noble on Fifth Avenue 🏰🗽 Thank you for the photos, @evansrjames #TheTower #MaryQueenOfScots @BNBuzz

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Flora Carr@floracarr_·1 Nis

A friend of mine is in San Francisco and paid a visit to the iconic independent bookstore @citylightsbooks… and spotted THE TOWER inside! 🏰 The shop is a city landmark and known for publishing Allen Ginsberg's ‘Howl’.

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James Evans@evansrjames·19 Mar

@mrcppu @Raja_Nirujogi @AnneRowlClinic @EuansCentre @UKDRI Congratulations @Raja_Nirujogi! 🥳

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MRC PPU@mrcppu·18 Mar

We are delighted to announce that Dr Raja Nirujogi, has been appointed as an Independent Investigator jointly between the Universities of Dundee and Edinburgh to undertake research centred on deciphering signalling pathways in amyotrophic lateral sclerosis ppu.mrc.ac.uk/news/raja-niru…

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Pluchino lab - Regenerative Neuroimmunology@Pluchinolab·8 Oca

Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons | Nature Biotechnology nature.com/articles/s4158…

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Rory Cellan-Jones@ruskin147·30 Ağu

Head spinning after a brilliant morning at the Francis Crick Institute meeting Prof Sonia Gandhi and her team who are mapping the Parkinson’s brain.

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Nature Portfolio@NaturePortfolio·20 Ağu

Machine learning can accurately predict subtypes of Parkinson’s disease using images of patient-derived stem cells, reports a study published in @NatMachIntell. go.nature.com/3qDl3yO

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UCL Brain Sciences@UCLBrainScience·14 Ağu

"We now hope to expand this approach to understand how these cellular mechanisms contribute to other subtypes of Parkinson’s." James Evans @evansrjames (@UCLIoN) on a new study involving @LabGandhi and the @TheCrick. Read in @Independent ⬇️ independent.co.uk/tech/scientist…

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UCL Brain Sciences@UCLBrainScience·11 Ağu

Machine learning can accurately predict subtypes of Parkinson’s disease using images of patient-derived stem cells, finds a new study by researchers at UCL and the Francis Crick Institute. @LabGandhi @evansrjames @UCLIoN @TheCrick Read more ⬇️ ucl.ac.uk/news/2023/aug/…

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James Evans@evansrjames·11 Ağu

A great collaborative effort from @LabGandhi @GurvirVirdi @DilanAthauda @MineeChoi @faculty_ai @MathewHHorrocks @EdBiophysics

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The Francis Crick Institute@TheCrick

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James Evans@evansrjames·11 Ağu

Very excited to share our latest work published in @NatMachIntell. We used ipsc-derived neurons, high-throughout imaging, and machine learning approaches to predict Parkinson’s disease subtypes. nature.com/articles/s4225…

The @LabGandhi team took part in an intensive coding course when the pandemic disrupted their research – and now they’ve published work with @faculty_ai showing that computer models can classify types of Parkinson’s from images of stem cells 🧠 @UCLIoN crick.ac.uk/news/2023-08-1…

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James Evans@evansrjames·11 Ağu

@Raja_Nirujogi @TheCrick @LabGandhi @faculty_ai @UCLIoN @GurvirVirdi Thanks Raja!

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The Francis Crick Institute@TheCrick·10 Ağu

The @LabGandhi team took part in an intensive coding course when the pandemic disrupted their research – and now they’ve published work with @faculty_ai showing that computer models can classify types of Parkinson’s from images of stem cells 🧠 @UCLIoN crick.ac.uk/news/2023-08-1…

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