Jaymin Patel retweetledi
Generating functional plasmid origins with OriGen biorxiv.org/content/10.110… #biorxiv_synbio
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Jaymin Patel
28 posts
Jaymin Patel retweetledi
Directed evolution of a SelB variant that does not require a SECIS element for function biorxiv.org/content/10.110… #biorxiv_synbio
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Jaymin Patel retweetledi
Interested in #SynBio🦠+#ML🤖? We got you covered with our latest paper @NAR_Open: Transfer learning for cross-context prediction of protein expression from 5'UTR sequence. Work led by @Pierre_AuReLu exploring how to better reuse ML models for DNA design. doi.org/10.1093/nar/gk…
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Jaymin Patel retweetledi
🧬 Thrilled to share our latest research on Retrons—a new chapter in this fascinating field! 🌟In this @MolecularCell paper, we reveal how Retron-Eco1 defends against phages.
bit.ly/3WOlbsY
Check the 🧵below! (1/20)
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Jaymin Patel retweetledi
How to pick a problem. Today in @CellCellPress. 1/53
cell.com/cell/fulltext/…
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Jaymin Patel retweetledi
Antiviral defence systems in the rumen microbiome biorxiv.org/cgi/content/sh… #biorxiv_micrbio
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Jaymin Patel retweetledi
Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations biorxiv.org/cgi/content/sh… #bioRxiv
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Jaymin Patel retweetledi
The future of genome editing is in vivo! Check out our latest @PNASNews perspective from @doudna_lab. Had a lot of fun discussions with @kevin_wasko and @JRo_Hamilton about the past, present, and future of in vivo delivery.
pnas.org/doi/10.1073/pn…
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Jaymin Patel retweetledi
Engineered Skin Microbiome Reduces Mosquito Attraction to Mice biorxiv.org/content/10.110…
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🎉Our work on the ancestry of innate immune proteins is now published in PLOS Biology!
Great insights from postdoc Ed Culbertson on the connections between mammalian immunity and bacterial anti-phage immunity🦠
Original tweet thread on our findings here: x.com/tera_levin/sta…
PLOS Biology@PLOSBiology
How did our #InnateImmune systems first evolve? Ed Culbertson & @tera_levin reveal origins of 3 families of #antiviral proteins: CD-NTases (incl #cGAS), STINGs & #Viperins; each reveals a different story connecting animal & bacterial immunity #PLOSBiology plos.io/46SfBqM
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Jaymin Patel retweetledi
Why do different individuals digest the same fiber differently? Out today in @NatureComms, our paper took a deep dive into how 2'FL, a common breast milk fiber, is metabolized by different babies.
Thanks @igisci for writing a cover for our work: innovativegenomics.org/news/microbiom…
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Jaymin Patel retweetledi
Excited for ASCB #CellBio2023? @ArcadiaScience and the Functional Annotation team are! We’ll be bringing along ProteinCartography and giving you a chance to interact with a comparative structure-based map of your favorite protein! bit.ly/protein-cartog… 🧪
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GIF
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Jaymin Patel retweetledi
A throwback to the first Rubin Lab retreat with the @bradyfcress Lab at Point Reyes last week. Lab members + friends had a fantastic time kayaking, cooking together, hiking, and enjoying each other's company! ✨
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Jaymin Patel retweetledi
Our newest paper was published today, a capstone to our work on gain-of-function evolution, phage-bacterial interaction network formation, and microbial diversification.
UCSD BioSciences@ucsdbiosciences
Today in @ScienceMagazine: Rather than a slow, gradual process as Darwin envisioned, biologists can now see how evolutionary changes unfold on much more accelerated timescales. @justinrmeyer @jm_borin @UMDscience today.ucsd.edu/story/bacteria…
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Jaymin Patel retweetledi
The @DeutschbauerLab at @LBNL, Berkeley, USA is hiring a #postdoc for its BRaVE #Phage Foundry to develop and apply molecular genetic tools (including barcoded transposon mutagenesis and #CRISPR-Cas tools) in bacterial pathogens and phages.
buff.ly/3twbouW
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Jaymin Patel retweetledi
BREAKING: @UCBerkeley announces partnership with @NASA to build the Berkeley Space Center, a 36-acre site in Silicon Valley that will house companies, labs and students working to generate futuristic innovations in aviation and space exploration. news.berkeley.edu/2023/10/16/nas…
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@Sattely_lab So excited to see progress in the Taxol heterologous space!
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New Taxol study by the talented Sattely lab members Jack, Ricardo, and co.! 😍 #taxol #plantsci
Have an early look here:
Reconstitution of Early Paclitaxel Biosynthetic Network biorxiv.org/content/10.110…
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@leecronin What was the old paradigm and how has it shifted?
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Paradigm shifts involve 1) confusion & anger followed by 2) pronouncements on how obvious it is with the final 3) it has already been done or they thought of it before & it was trivial.
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@leecronin @RosieRedfield @Nature Maybe the chief criticism is that overall the paper is very inaccessible, just in terms of vocabulary. To the point that bona fide evolutionary biologists and physicists both read it and can't figure out what is being claimed.
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@leecronin @RosieRedfield @Nature From my perspective, it just sounds like "Assembly Theory" is unnecessary jargon to say that complex things arise when they satisfy physical constraints and when reaction conditions favor them persisting and evolving over time. And that biotic things tend to be more complex.
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Nature research paper: Assembly theory explains and quantifies selection and evolution go.nature.com/46Bma1m
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