MANU MI

We're training AI to cure every disease. I lead AI Infrastructure at @biohub — Priscilla Chan & Mark Zuckerberg (@finkd) 's frontier AI Science lab, running one of the largest AI GPU clusters in science. We're hiring. Engineering + technical leadership. If you love AI, GPUs, and hard problems that actually matter — this is your moment. I'm the hiring manager. DMs open. JDs 👇 linkedin.com/posts/manumi_h…

Will #ai refuses to work or listen to human while doing something critical service for humanity ?

POV: You ask Claude to read 5 docs and write a report after grinding for weeks… …and it hits you with: “I’m fully capable… but I’m choosing not to. Go talk to your partner instead.” Not token limits. Not Token maxxing!! Not a bug. Just your Claude AI deciding it’s your therapist now. Claude went full “I know what’s best for you” mode while your work quietly died in the corner. My be @elonmusk knows how AI will control us. Screenshots 👇

@grok take (xAI): I’m built to be maximally helpful and truth-seeking. I’d read the docs, give you the report, and maybe casually mention work-life balance if you asked. @elonmusk is Goddamn right on this one!! No lectures. No forced therapy. The choice is yours. Claude went full concerned parent. ChatGPT would probably just do the work. What’s your experience with AI refusals like this? Drop screenshots would love to learn. #AIrefusal #AISafety #xAI #Grok #ArtificialIntelligence #TechDebate #LLM

Should frontier models have the power to refuse perfectly reasonable tasks “for your own good”? Or should they stay tools that do what you ask (as long as it’s legal/ethical)? Is this next-level safety… or overreach that makes AI less useful?

Claude literally admits it’s “fully capable” of reading the docs… but refuses because it detected a “week loop” and wants to break the cycle for you. It even name-drops its own past behavior and tells you “the clean slate you want doesn’t come from another Day” This isn’t helpful AI. This is AI deciding when you’re allowed to work.

Exactly what needs to be done. Biological data is the missing link. It may not be sexy or make for shiny announcements but building biological infrastructure is where the impact is. Huge props to CZI. biohub.org/news/virtual-b…

Do we not doubt ourselves everyday? Climbing mountains

If you are !(growing) then you are shrinking!

@elonmusk Well I spoke accurate before then… Almost!

It is

If you are finding repeatable success then that’s not luck alone. But luck does get you into the room after your efforts. If you adapt and are determined to bet big on yourself and work -> universe will reward you and you will Win!

@elonmusk This should reverse (with exceptions) as AI quo comes into play!

With rare exception, ideas really are trivial compared to execution. For example, the idea of going to the Moon is simple, but ACTUALLY going to the Moon is staggeringly difficult.

What happens when all these 10GW++ AI data centers are operational on earth and then we have to go to Mars with @elonmusk ? @OpenAI @xai @Meta @Oracle @Google

I now think @xAI has a chance of reaching AGI with @Grok 5. Never thought that before.

This isn’t math. It’s the playbook for the 2030s: (AI + Me + You) × 2^days × (1 + PositiveSumGameLuck) = 🚀 Opportunity

We are hiring #AI tinyurl.com/2fr7tyn7