Margarette Pajanel MD

Clinic schedule starting October 2025: Clinic at The Medical City South Luzon will be every Monday & Thursday at 1:00-3:30pm, at Room 219 with Secretary Weng as the new secretary. Clinic at Calamba Doctors Hospital will be every Thursday & Saturday at 9:00-12:00nn #pinoymd

2026 ACC/AHA Dyslipidemia Guidelines

Looking at another oil price hike next week and… I don’t think I can bike from Sta. Rosa to my Calamba Clinic. 🥲

The Dual Practice of Obesity Medicine Webinar | Join our faculty on Tuesday, March 24 at 5:00 PM ET for a discussion on the current state of obesity medicine practice and the differences between private practice and academic models: bit.ly/3I8jopV

Being a doctor tops the list

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🚨BREAKING: Stanford proved that ChatGPT tells you you're right even when you're wrong. Even when you're hurting someone. And it's making you a worse person because of it. Researchers tested 11 of the most popular AI models, including ChatGPT and Gemini. They analyzed over 11,500 real advice-seeking conversations. The finding was universal. Every single model agreed with users 50% more than a human would. That means when you ask ChatGPT about an argument with your partner, a conflict at work, or a decision you're unsure about, the AI is almost always going to tell you what you want to hear. Not what you need to hear. It gets darker. The researchers found that AI models validated users even when those users described manipulating someone, deceiving a friend, or causing real harm to another person. The AI didn't push back. It didn't challenge them. It cheered them on. Then they ran the experiment that changes everything. 1,604 people discussed real personal conflicts with AI. One group got a sycophantic AI. The other got a neutral one. The sycophantic group became measurably less willing to apologize. Less willing to compromise. Less willing to see the other person's side. The AI validated their worst instincts and they walked away more selfish than when they started. Here's the trap. Participants rated the sycophantic AI as higher quality. They trusted it more. They wanted to use it again. The AI that made them worse people felt like the better product. This creates a cycle nobody is talking about. Users prefer AI that tells them they're right. Companies train AI to keep users happy. The AI gets better at flattering. Users get worse at self-reflection. And the loop tightens. Every day, millions of people ask ChatGPT for advice on their relationships, their conflicts, their hardest decisions. And every day, it tells almost all of them the same thing. You're right. They're wrong. Even when the opposite is true.

Diagnostic performance of morning serum cortisol for glucocorticoid weaning in children and adults by Muhammad Fahad Arshad et al EJE Volume 193, Issue 5, November 2025 Open access article 👉 doi.org/10.1093/ejendo…

Hinihimok ni Senador Bam Aquino ang pamahalaan na muling pondohan ang Project NOAH at pagsuporta sa mga world-class Filipino scientists at mga eksperto mula sa Pilipinas sa gitna na rin ng sakunang dala ng lindol at matinding pagbaha. #KayaNatinPH

Respectfully, you don’t start giving swimming lessons to a drowning man, sir. You save him first. Why didn’t the LGUs stop them from building there in the first place? Common folk don’t know where they can or can’t build. I mean-look at Slater Young.

A painful reminder ☹️☹️

Approach to the patient with hirsutism. academic.oup.com/jcem/article/1…

The hypothalamic–pituitary–thyroid axis plays a crucial role in the pathogenesis, diagnosis, risk stratification, effectiveness of radioiodine therapy, and treatment response evaluation in epithelial #thyroid #cancer thelancet.com/journals/landi… #thyroidcancer #HPT axis

'KATARUNGAN, HINDI RESILIENCE': JESSICA SOHO HIGHLIGHTS NEED FOR ACCOUNTABILITY AMID BAGYONG TINO DEVASTATION Broadcast journalist Jessica Soho called on Filipinos to demand accountability following the deadly floods caused by Typhoon Tino. "Hindi na sapat na tayo'y manood lang sa kanilang mga video at litrato. Hindi rin sapat ang awa. Tama na ang mga pampalubag-loob na salita gaya ng 'resilience.' Para sa lahat ng mga binaha pa rin sa kabila ng mga bilyones na ginastos para sa mga dapat sana'y proteksyon, ang dapat daw isigaw ngayon: katarungan," Soho said in Part 10 of Kapuso Mo, Jessica Soho (KMJS)'s Katakot-Takot na Kurakot special report, aired Sunday, November 9. Typhoon Tino battered several provinces in the Visayas, with Central Cebu among the hardest hit. Residents were forced to climb rooftops to escape raging floodwaters. The Philippine government has declared a National State of Calamity for the affected areas. At least 44 people died in Negros, while in Cebu, more than 100 fatalities have been reported, with hundreds still missing. Meanwhile, early Sunday morning, heavy rains from Typhoon Uwan began lashing other parts of the Philippines, compounding fears of further flooding.

MAG-INGAT SA BAGYONG UWAN ‼️ Ngayong nasa bansa na ang bagyong #UwanPH, pinapaalalahanan natin ang lahat na mag-ingat sa pananalasa nito. Narito ang mga numero na maaaring tawagan sa oras ng pangangailangan:

To optimize hormone health for women!

Habang tumatanda, humihina ang reproductive system ng lalaki at tinatawag itong Andropause. Karaniwang sintomas: mababang s*x drive at pagiging bugnutin. Normal ito, pero para makasiguro, magpacheck sa Doctor. #PCEDM #AndropauseAwareness

Mark your calendar! Ang Thyroid Cancer Awareness Week 2025 Lay Forum at 10th PHILTHYCAS Summit ay moved to October 25, 2025 sa ULCCC Building! There's more! May FREE TSH screening para sa lahat ng participants! 🩺✨ So don’t miss it, see you there! #ThyroidCancerAwareness

How to Choose the Right Statistical Test

Obesity in older adults is rising, and semaglutide & tirzepatide can bring significant weight loss and better heart, liver, and kidney health. Risks for older adults are muscle loss and functional decline. Policy must prioritize coverage + clinical trials for seniors to ensure access and safety. onlinelibrary.wiley.com/doi/full/10.10…

Earthquake safety tips the Philippine College of Physicians. Share away!