Rob Isenberg

@piergeli Hi Pierre. No plans I’m afraid… I’ve moved on and it’s not such a big area of focus for me.

@robisenberg any plan for a second edition of Docker for Rails Developers now that it is more integrated in Rails 7 and tools like Kamal?

🚨#OreoVsStatin - PUBLISHED!🚨 mdpi.com/2218-1989/14/1… @Oreo cookies were 💥2X as potent💥 at lowering my LDL cholesterol (LDL-C) compared to high-intensity statin therapy! What you NEED to know... 👉This was a metabolic demonstration, a 'do not do this at home' experiment that makes no 'health' claims about cookies or cholesterol. 👉The purpose was to BOLDLY test a prediction of the Lipid Energy Model #LEM, i.e. that adding in carbs, including in the from of an Oreo cookies 'addition' (not carb-fat swap) would lower LDL-C in an LMHR on a #keto diet Why Oreos? ... It's (productively) provocative! 😱 Research on #cholesterol on #keto diets and the #LEM and #LMHR phenotype has so much to teach us about human lipid metabolism! ... But how do I (we) communicate the scientific 'awe' that we feel to the greatest number of people (as well as force a conversation about #LMHR and #LEM that needs to happen)? ... A dramatic demonstration designed to turn heads might work! It's not 'just click bait' ... it's 'legit-bait' I want YOU to feel the 'shock and awe' I feel every day studying this topic. And I want you to engage in the research journey. What you need to do... or should do... 🙏PRETTY PLEASE 🙏! 👉PLEASE WATCH 👀 VIDEO ABSTRACT here (<8 min): youtu.be/L1mMnnyJrgk 👉 SHARE THIS LINK to the paper itself in a quote RT or original Tweet of your own: mdpi.com/2218-1989/14/1… ... doing so helps promote the work and provoke the discussion ... and feel free to tag in your favorite influencers (or least favorite 😉)... A HUGE thanks to the senior author and expert lipidologist @Lipoprotein for his guiding wisdom, insightful thoughts, and always open and curious mind. And to @realDaveFeldman, my friend, research wife, and the '#LEM daddy' Finally... there will be a LOT of coverage of this experiment. Keep in mind, we are not making any health claims, but through a dramatic demonstration, highlighting an uncomfortable tension that arises from a prediction of the Lipid Energy Model, and that is consistent with prior data (7+ papers, including 'highest tier' data like our recent meta-analysis of 41 RCTs). Science is supposed to embrace such uncomfortable questions... so, join us in being curious and advocating for much needed research on #LEM and #LMHR so we can make sense of what observations like this really mean... STAY CURIOUS 🤔

@allenf32 Who says the “debt” has to come down? Read The Deficit Myth by Stephanie Kelton and you’ll realise you fundamentally misunderstand fiat currencies.

open question for fiatbros: how do you think this is going to end? seriously, what's your plan? does the debt ever come down? does inflation ever stop? if so, *how*? *precisely how*? "see no evil, hear no evil" is not an answer. evil is afoot and you need to act.

@JinishC Wow, thank you. I’m so pleased you’re finding it useful.

@robisenberg your book - Docker For Rails Developers is proving to be one of the life changing books for me. I cannot thank you enough. Really.

@searls @searls would something like this work? github.com/gerrywastaken/…

I need Ruby help: • I want to run tests with Bundler • The VS Code launcher wants the ruby-debug-ide gem to be present • I don't want to add a gem specific to my local devtools to the committed Gemfile/lock files Can I add a gem to bundler locally without causing git churn?

@Austen Sure, it’s clearly not the same as the actual laws of physics, but it is based on how banking operations actually work. And since it literally offers no policy recommendations other than the Job Guarantee, I’m not sure which “terrible policy recommendations” you’re referring to.

@robisenberg Ya it’s very much not like the laws of physics and comes embedded with terrible policy recommendations

So… we accept that the Laws of Physics are a bad idea, right?

I like @Austen, but his tweet shows a fundamental misunderstanding. He’s talking about MMT as if it’s something we “do” or “have done” rather than how things work. It has only one single policy recommendation: the Job Guarantee programme.

(MMT is an economic lens based on understanding the *mechanisms* of *how the banking system actually works* - unlike other economic theories that are not tied to these realities)

@mlambie However, it’s also a bit outdated and doesn’t use the latest approach(es) I’d recommend now that we have things like VSCode Devcontainer capability etc, or some performance tricks I’ve found since for the mac.

@mlambie I think it’s still a great intro to Docker (for Rails Developers) - so if you’re new to Docker and/or haven’t fully got your head round it, still good. I believe it largely should still work with Rails 7 (though have not tested specifically).

@robisenberg is Docker for Rails Developers still the resource you'd recommend first, and is it relevant to Rails 7 or a little outdated?

@The_Nutrivore @streetsigns @realDaveFeldman The term “sophist”, at least in some definitions, has connotations of wilful deceptiveness which I find unwarranted based on my own experiences with @realDaveFeldman.

@The_Nutrivore @streetsigns @realDaveFeldman To me, I think intent plays a big part. I find it a bit harsh to use hostility and attempts at ridicule towards someone that is well-intentioned (a subjective assessment) and trying their best to get to the “truth” even if you find their model contradictory.

In the interest of furthering healthy scientific discourse, I'm extending a good faith invitation to @realDaveFeldman to unblock me and discuss his work. For the time being, I'm ending all hostilities toward him on my end. Dave, let's call a truce and discuss the science. ✌️

@The_Nutrivore @streetsigns @realDaveFeldman I don’t know what @realDaveFeldman has done that makes you consider him wilfully deceitful. I’ve found he bends over backwards to highlight that high LDL in LMHRs is not considered “safe”, and that more research is needed e.g. cholesterolcode.com/guest-post-the…

@The_Nutrivore @streetsigns @realDaveFeldman I can see the argument for this approach and how it can be a moral good. My only problem is that it sets you up as the arbiter for whether someone is a “confirmed sophist” or not and therefore whether it’s fair game to target them with your “hostilities”.

1/2 🚨🚨🚨BREAKING🚨🚨🚨 👉👉👉Long awaited #LipidEnergyModel/#LEM Hypothesis Paper is now published!!! 🙏Please Retweet🙏 👉Why #LDL #Cholesterol might ⬆️ on #keto 👉How #LEM could explain #LMHR phenotype 👉Implications for lipid metabolism overall mdpi.com/2218-1989/12/5…

🚨🚨🚨BREAKING: New #LMHR Case Study- Please RT!🚨🚨🚨 👉 LDL ↗️ 95 to 545 on keto diet with >4:1 unsaturated/sat fat ratio 👉 ↗️ BMI=↘️ LDL, even with higher sat fat 👉No🧬abnormalities found to explain phenotype 👉CCTA at 2.5 years = no plaque doi.org/10.3389/fendo.… 1/2

It costs $0.00 to retweet the art of a self-taught, Black artist from South Carolina. Many of my pieces are painted with rain or melted snow. I sell my work here: mentnelson.com. My next collector could be on your timeline

@realDaveFeldman @Lpa_Doc Do you know if Lp-PLA2 test works like this too and tracks with the number of LDL-P, even though there may be a quantitative difference on each particle?

@Lpa_Doc Yes ~ this 👆 Hence my great appreciation for the OxPL-ApoB assay (it’s not just because I’m a fan of @Lpa_Doc) cholesterolcode.com/preliminary-da…

The "OxLDL" assay correlates w/ LDL because the antibody used 4E6 detects apoB- can compete binding to OxLDL with LDL (which should not happen) pubmed.ncbi.nlm.nih.gov/8950769/ When one spikes a sample with unoxidized LDL it picks it up almost as well as OxLDL. LDL/"OxLDL" track closely