Chris West

16 posts

Chris West

Chris West

@timeminer05

Katılım Kasım 2017
108 Takip Edilen13 Takipçiler
Chris West retweetledi
unusual_whales
unusual_whales@unusual_whales·
President-elect Donald Trump said the U.S. is going to become the global leader for cryptocurrency.
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Chris West retweetledi
unusual_whales
unusual_whales@unusual_whales·
ECB chief Lagarde: The outlook is darkening.
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Chris West retweetledi
unusual_whales
unusual_whales@unusual_whales·
White House says Biden has no intention of sending US troops to Ukraine.
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Chris West
Chris West@timeminer05·
@cameronks 3. Thus: start severe patients on drug treatment upon hospital intake to suppress further hijacking of blood by the virus, then give them a blood transfusion of new red blood cells immediately that are unhijacked. If all this is true, we would see rapid patient improvement.
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Chris West
Chris West@timeminer05·
@cameronks 2. Drug treatment and intubation once patient is critical will rarely work because tissues/organs are already damaged, blood can't carry O2, and the body is too weak to produce new red blood cells able to carry Fe (and thus oxygen/CO2) even if drugs inhibit more hijacking.
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Chris West
Chris West@timeminer05·
@cameronks 1. Starting drug treatment while symptoms are mild keeps virus from hijacking too much blood, enabling a still-healthy body to mount an immune response. Explains why early drug treatment (first week of symptoms) is often successful.
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Chris West
Chris West@timeminer05·
@cameronks - The inflammation in the lungs results from the lungs not being able to perform the oxygen/CO2 exchange, and would therefore appear to be a SECONDARY result of the hijacking of the blood. The lungs not working is a result of lack of O2 in blood, not the cause of it.
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Chris West
Chris West@timeminer05·
@cameronks patient were being suffocated. Even when a patient can breath (fill lungs with air), the oxygen isn't getting to the cells in their body.
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Chris West
Chris West@timeminer05·
@cameronks - If the computer modeling is right, it shows that the virus hijacks our [red] blood [cells] and makes it unable to carry O2 to a patient's tissues/organs, and likewise unable to carry CO2 out of them. This would lead to organ and tissue death, roughly in the same way as if a
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Chris West
Chris West@timeminer05·
@cameronks - The paper modeled these and found that the proteins produced when COVID replicates "collaborate" to knock iron ions out of heme groups (HBB) and replace them with one of the proteins. This makes the red blood cell unable to transport O2 and CO2!
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Chris West
Chris West@timeminer05·
@cameronks - Inside our red blood cells, there is a molecule called hemoglobin, which contains heme groups. Each heme group is a molecular "ring" (called a porphyrin) that can hold an iron (Fe) ion inside. Having an iron ion inside is what allows this heme to carry O2 (and CO2) in our blood
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Chris West
Chris West@timeminer05·
@cameronks - Using computational analysis (modeling the behavior of a molecule in a computer), they've worked out the probable mechanism by which SARS-nCov-2 wreaks havoc on patients, as well as why chloroquine and favipiravir seem to work.
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Chris West
Chris West@timeminer05·
@cameronks Might not even be a respiratory illness after all and that's just a byproduct of the wreckage it makes in blood hemoglobin (thus making ARDS a symptom not a cause). I wish this would get more traction because this could change the way we approach COVID19 globally.
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Chris West
Chris West@timeminer05·
@cameronks From a friend in the medical field: “Hypothesizing that covid-19 is a primary hematologic infection rather than respiratory. This is an analysis done on a computer to study the virus. A lengthy read but it is what we are seeing in these patients.” (See below for summary)
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