Kevin Yang

13 posts

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Kevin Yang

Kevin Yang

@yangkl96

Proteome bioinformatician and PhD student at the University of Michigan

Katılım Ekim 2021
42 Takip Edilen60 Takipçiler
Kevin Yang
Kevin Yang@yangkl96·
@lgamon It was great meeting you irl Luke! I'll let the lab know and will certainly take you up on your offer
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Luke Gamon
Luke Gamon@lgamon·
@yangkl96 Great to meet you Kevin! Please drop by the lab next time you’re in Copenhagen 👍 Oh and say hi to the fragpipe team for me!
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Kevin Yang
Kevin Yang@yangkl96·
Honestly one of the coolest and best organized hackathons/conferences I've been to. I learned so much about the nuances of single cell data from the other attendees and had a great time socializing. Booking my ticket back to Copenhagen soon
Erwin Schoof@erwinschoof

Kevin Yang from the @nesvilab closing the data analytics session by showing the power of MSFragger for scp-MS - incredible what free, academic software can do! #iSCMS2024

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Kevin Yang
Kevin Yang@yangkl96·
Honored to be named a Rackham Predoctoral Fellow. It feels incredibly validating to have my work recognized and to connect with colleagues I haven't seen in a while
Alexey Nesvizhskii@nesvilab

Congratulation to Kevin Yang who has been named a Rackham Predoctoral Fellow. Kevin is the developer of #MSBooster and his thesis is on integration of deep learning models for improved peptide identification in MS-based proteomics. More cools things by Kevin in the next FragPipe!

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Alexey Nesvizhskii
Alexey Nesvizhskii@nesvilab·
MSBooster manuscript led by @yangkl96 is out! In tandem with Percolator, it improves identification rates in #FragPipe using deep learning-based predictions (from DIA-NN). We illustrate it using HLA peptidomics, direct DIA, single-cell, and timsTOF data. nature.com/articles/s4146…
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Alexey Nesvizhskii
Alexey Nesvizhskii@nesvilab·
New preprint led by @fcyucn describes MSFragger-DIA for direct peptide identification. Illustrated using single-cell, phospho, GFP-DIA, large-scale studies. One-stop analysis of DIA proteomics data using MSFragger-DIA and #FragPipe computational platform. biorxiv.org/content/10.110…
Alexey Nesvizhskii tweet media
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Kevin Yang
Kevin Yang@yangkl96·
Thankful for everyone who has been using and providing feedback on #MSBooster in #FragPipe. Excited to showcase the flexibility of the software, and looking forward to adding new features in the near future. Preprint out now!
Alexey Nesvizhskii@nesvilab

#FragPipe users have been enjoying #MSBooster (led by @yangkl96) for a while, but here is the preprint. Rescoring PSMs using deep learning-based predictions, demonstrated using HLA peptidomics, direct DIA, single-cell proteomics, and timsTOF applications. biorxiv.org/content/10.110…

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Kevin Yang
Kevin Yang@yangkl96·
@MiguelCos @nesvilab For TMT Integrator, you can cite the CPTAC papers "Quantitative proteomic landscape..." Djomehri et al 2020 (printed in GUI Run tab) and "Integrated proteogenomic characterization..." Clark et al 2019. For MSBooster, we will have a preprint out very soon. Thanks for waiting
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Miguel Cosenza-Contreras
Miguel Cosenza-Contreras@MiguelCos·
@yangkl96 @nesvilab Is there a way I can cite this? I am preparing a manuscript in which I used FragPipe for TMT quant but I can't find a way to cite TMT integrator or MSBooster. I think it would be unfair to only cite MSFragger and Philosopher. @nesvilab Any suggestions?
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Kevin Yang
Kevin Yang@yangkl96·
Excited to be presenting at my first ASMS! Come check out our new addition to Fragpipe, MSBooster for generation of deep learning-based features for PSM rescoring. Thanks to @nesvilab for guiding me through my first year in proteomics. Poster at WP110 #ASMS2021
Kevin Yang tweet media
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Kevin Yang
Kevin Yang@yangkl96·
@MiguelCos @nesvilab The default prediction model is only shifting TMT fragment peaks, but it is compatible and should not give empty results. Could you send to our github issues? I do not think this is an MSBooster issue
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Miguel Cosenza-Contreras
Miguel Cosenza-Contreras@MiguelCos·
@yangkl96 @nesvilab I a very happy about this implementation. For what I read in the poster, do I understand correctly that TMT labelling is still not compatible with MSboost? I tested it with the TMT pipeline in FragPipe and got empty results from TMT-integrator.
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Kevin Yang
Kevin Yang@yangkl96·
@LukaszPK If you have the ASMS2021 app, it should be under the Informatics: Peptide ID and Quant poster section for Wednesday
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