Sandip Lahiri

Good morning. Congratulations to the author of the post for the classical click-bait AI-slop misinformation that won millions of views and used "scienceploitation" for engagement farming. Enjoy the payout. I am sure this guy has received promotion money from the NOW supplements manufacturer also. Here is the truth, which will hardly receive any views. Also, activating Brandolini's Law: "The amount of energy needed to refute bullshit is an order of magnitude bigger than to produce it". L-theanine is a relatively safe amino acid found in tea. It may have mild calming effects in some people. But this post takes weak, preliminary, small-sample evidence and presents it as though it is established neuropharmacology. It uses scientific-sounding language to make a dietary supplement sound like a precision brain drug. It isn't. The confidence of the claims vastly exceeds the quality of the evidence. That gap between confidence and evidence is the textbook definition of misinformation. Only legal compound that changes brainwaves on EEG within 40 minutes This is spectacularly wrong. Caffeine, alcohol, benzodiazepines, antihistamines, nicotine, melatonin, and dozens of other legal substances produce measurable EEG changes within minutes. This claim alone tells you the person writing this has no background in neuroscience or pharmacology. The mechanism description sounds impressive but is oversimplified to the point of being wrong. L-theanine is structurally similar to glutamate, yes. But describing it as sitting on glutamate receptors and "partially blocking the signal" is a gross simplification of what are weak, inconsistent findings mostly from animal and in-vitro studies. The actual receptor-level pharmacology in living human brains at oral supplement doses is not well established. Saying "your excitatory system downshifts" as though this is a reliable, predictable drug effect is not supported by the evidence. GABA levels rise, serotonin and dopamine both increase. Again, mostly from animal studies using doses that don't translate cleanly to a 200mg human oral dose. You cannot cite rat brain tissue data and present it as what happens in your brain after swallowing a capsule. The alpha wave claims... Yes, some small studies show modest alpha wave increases. But alpha waves are not a "meditation and flow state frequency." That is pop neuroscience. Alpha activity increases when you close your eyes and relax. It is not a marker of cognitive superiority or deep focus. Framing alpha waves as something "people spend years trying to access through breathwork" is pure marketing language dressed up as science. The 2016 multitasking study Small sample sizes, single studies, no replication at scale. One small study is not proof of anything. This is how supplement marketing works: find one favourable small trial, present it as settled science, ignore the dozens of studies with null or mixed results. Blocks the jitter pathway without touching the alertness pathway There is no such thing as a single "jitter pathway" or "alertness pathway." This is made-up oversimplification. The actual evidence on L-theanine plus caffeine synergy is modest, from small trials, and far from the clean mechanistic story presented here. Dont waste your hard earned money on supplements that you never require. The ones who post these never use such garbage products themselves. Much like actors Ajay Devgn and Shah Rukh Khan in Gutka ads or Cristiano Ronaldo featuring Herbalife products.

My Instagram account was briefly suspended today. Here is why. @instagram caters to maintaining misinformation, while suspending those who call out misinformation. An Ayurvedic practitioner Vaidya Ravinder Kaushik (instagram.com/drravinder.261…) of Anantya Healthcare based in Gurgaon (anantyahealthcare.com/pages/our-foun…) was responsible for the brief suspension of my Instagram because I called out his fraud practices - including his claim of Ayurvedic treatment of Duchenne Muscular Dystrophy. Here is my post that was taken down because the so-called Ayurvedic "expert" in "genetic medicine" could not tolerate scientific criticism - that was harming his business. 1/11

Today, on my birthday, I ask you all to share this message tagging @narendramodi @MoHFW_INDIA @JPNadda @eduminofindia @dpradhanbjp and ask 1)Only CDSCO approved medicines are sold in the pharmacies, and not FSSAI approved products, especially chocolates, biscuits, sugary liquids, misbranded tetrapacksetc 2)Make every school, every home, every office, every factory, every construction site, every public transport, and every public place safe by ensuring CPR training and First Aid training(especially for choking, seizures, poisoning, and trauma) is imparted to every one. 3) Ensure car seat and belt guidelines for children, helmet guidelines for children, and seat belt guidelines for those sitting in the rear seat are formulated and enforced 4) Teaching children about 'OK touch' and 'Not OK touch' is incorporated in the school curriculum. #childsafety #medicationerrors #publicsafety #CPR #FirstAid

still the best tweet

Can’t get my AI agents to work properly. Can anyone help?

When Trump pussies out tonight, his message will go something like this: "I am pleased to announce that Iran has agreed to save the lives of its great and wonderful people and make a deal! Therefore, I am postponing the Total and Complete Devastation of their bridges and nuclear powerplants for one week. There is still a chance for Iran to become a respected country, the likes of which the world has never seen, if they do the right thing. We have already won this war, Totally and Completely. Do the right thing! Thank you for your attention to this matter!" What do you think? Did I miss anything? 😏

To stop ants coming in to your house leave a saucer of milk outside. The adult ants drink it & it has an effect on ant reproduction. The young are born without toes so they can't climb in to your walls. This effect is called lack toes in toddler ants.

I saw someone jogging past my house and it really motivated me to get up and close the blinds.

Macro analyst #26 explaining to 100K subscribers how the situation in the Straits of Hormuz impacts the economy.

My uncle was always my role model...a voracious reader and a deeply curious man. Even in his early 60s, he spends two hours every day learning new things. But he made a mistake that nearly cost him his life. He is a long-standing diabetic. Two years ago, his HbA1c was 8.9, and his endocrinologist started him on insulin. Once he started working out and saw his sugars stabilizing, he began to experiment. He eventually stopped his insulin entirely, switching to homeopathy and brisk walking. As a doctor, I was vocal about my concerns. I told him this wasn't about "allopathy vs. homeopathy," it was about evidence-based medicine. He was adamant, believing his physical activity would compensate for the lack of insulin. Yesterday, he was admitted to the ICU. His sensorium had deteriorated, and his HbA1c had climbed to 11.1. He is out of danger now, but it was a terrifyingly close call. If a man as brilliant and well-read as my uncle can be swayed by the "natural" narrative and the "lifestyle alone" myth, the general public stands no chance. Physical activity is an adjunct, not a replacement for essential medication in advanced diabetes. Please, follow the science and the specialists, not the anecdotes

This. Put your money on an A.I like Claude Opus or Gemini Pro. Feed it your demographics. Add your cultural/regional dietary preferences. Mention any comorbid conditions and medications you are on. Tell it your locality. Ask for a science-based dietary prescription tailored for you. The response will beat any of the so-called celebrity nutritionists in India. Want to make it better? Feed in your daily schedule - physical activity wise and work wise and it will also give you a perfect exercise/ physical activity regimen scheduled for immediate action. Nutritionists and Dietitians that I still come across keep telling patients to have honey-lemon water and green-tea on empty stomach to boost metabolism and digestion. Utter nonsense and garbage advice they keep giving. A.I is what I use to tailor special diet prescriptions for my advanced liver disease patients. Dietitian and Nutritionist job is one thing that will disappear in the future because of AI.

The UAE's downfall is the region's biggest redistribution of economic power since WWII. Start with Saudi Arabia. Its stock exchange gained while Dubai's lost $120bn. Riyadh stayed open while Dubai took a missile. British Airways cancelled Dubai through to May and kept Jeddah flying. Saudi Arabia's East-West pipeline now delivers 7 million barrels a day directly to Yanbu on the Red Sea, bypassing Hormuz entirely. That oil then moves through the Suez Canal. Every barrel that Riyadh reroutes is a barrel that no longer makes Dubai's Fujairah relevant. This is the structural transfer Dubai's planners feared for a decade. It is happening in real time under Iranian fire. Oman is the second winner. Muscat is the only Gulf capital untouched. Qatar Airways ran relief flights from Muscat when Doha was paralysed. SalamAir was selling tickets at UAE-Oman land border crossings. British evacuation flights for 138,000 stranded UK nationals departed Muscat. Oman positioned itself diplomatically as the only GCC state to condemn Operation Epic Fury and maintain back-channels with Tehran. Iran's new Supreme Leader explicitly signalled that Tehran values that relationship. Oman does not inherit Dubai's model. It inherits Dubai's irreplaceability. Turkey is absorbing the aviation gap. Istanbul is the primary exit point for private capital fleeing the Gulf corridor. Senior finance executives were paying $100,000 per seat on Istanbul-bound private jets departing Dubai. Armenia and Azerbaijan are carrying the Europe-Asia overflight traffic that used to run through Emirati airspace. The northern Caucasus corridor is now the functional alternative to the Gulf route. Every aircraft that reroutes through that arc strengthens the case for Istanbul as the permanent regional waypoint. Algeria and Libya are collecting the energy premium. As Qatar declared force majeure and Gulf LNG exports froze, Algerian gas to Europe commanded prices not seen since 2022. Dutch TTF benchmarks nearly doubled. Algeria has limited surge capacity, but it does not need volume. It needs price. The war gave it both. Jordan and Egypt are repositioning on logistics. Egypt is providing alternative freight routing to the Gulf via its ports and the SUMED pipeline. Saudi oil from Yanbu now moves through Suez to Mediterranean markets. Egypt's fertiliser and aluminium exports are commanding higher prices as Gulf supply froze. Jordan's Port of Aqaba is the one functioning overland corridor between the Gulf and Syria with operational border infrastructure. Iraq is already moving some oil south by road tanker through Jordan rather than through Hormuz. None of these countries designed this outcome. They did not need to. Dubai designed its own fragility by building an entire state model on the premise that it could remain geopolitically neutral while aligning militarily with Washington and economically with Tel Aviv. Abu Dhabi's intelligence and defence integration with Israel made the UAE Iran's primary Gulf target from day one. The stability premium was priced on a fiction. Saudi Arabia, Oman, Turkey, Algeria, Jordan and Egypt are now pricing the reality.

Qatar and Emirates airlines are fully refunding tickets as far ahead as July travel. Not even rescheduling anymore. Make of that what you will.

My accountant after I told him I've added a 14th source of income

Boomers on Facebook getting duped by AI slop

1/2 Dear Friends, I never wanted to become a doctor. I always wanted to write and tell stories. And yet, over the years, medicine gave me the most extraordinary stories I could never have imagined - stories that lived in hospital corridors, outpatient rooms and inside terrifying ICUs; in the trembling hands of a father carrying his jaundiced daughter, in the silence between a prognosis spoken and a family's world shattered. Today, I am proud and deeply moved to announce my first book, The Liver Doctor: Stories of Love, Loss and Regeneration, published by @HarperCollinsIN . This book is where my two worlds finally collide. My childhood love for writing and telling stories. And my adultdhood, as a medical doctor. Through the lives of real patients and their families - their courage, their grief, their impossible choices - I tell the story of the most misunderstood, most indispensable, and only self-regenerating organ in the human body: the liver. But this is not just a medical book. It is a journey through ancient myth and modern science, through Prometheus and Wilson's disease, through Mesopotamian clay tablets and liver transplant waiting lists, through the history of healing itself. I wrote it for doctors, so they may remember why they chose this life. I wrote it for patients and families, so they may know when to fight and when to find peace. I wrote it for myself, to make peace with what I have lost and what I will lose. This book shoulders that one truth I have learned in all my years at the clinical bedside: I did not become a doctor to help people cheat death, but to help them understand it. This book is my offering - to medicine, to storytelling, and to you. Lose yourself in these pages, as I have. Pre-orders are open now The Liver Doctor : Stories of Love, Loss and Regeneration - amzn.in/d/0duTenmW

The cholesterol wars are over. LDL won. New guidelines. Four landmark trials. An oral PCSK9 inhibitor that matches injectables. And data proving we should be treating patients we currently aren't. Here's everything clinicians need to know. 🧵