Brain-Immune Communication Lab

And it's out! The BIC lab presents our new perspective article on "Immune Control of Brain Physiology" - fresh off the press at @NatRevImmunol nature.com/articles/s4157… wonderful synergy @_marikovacs @Ali_MoussaSamir and twitterless Amaia Dominguez-Belloso.

Very happy to share this recent @AleksDeLab production!

A massive global review just confirmed it. Clinical trials + real-world data from 132 million people across the globe. The HPV vaccine doesn’t just reduce cervical cancer. It almost eliminates it. Yes, you read that right. Girls vaccinated before 16 have an 80% lower risk of cervical cancer. Not a small reduction. Not “maybe.” Eighty percent. The protection isn’t only for the cervix. HPV causes cancers of the anus, penis, vagina, vulva, mouth, throat - the vaccine blocks the virus before the damage ever starts. This isn’t one study. It’s Cochrane, the gold standard of independent science. They analyzed clinical trials + real-world data from 132 million people across the globe. Not pharma PR. Not a lab press release. Global. Independent. Verified. The #1 fear? Side effects. Here’s what the data says: Arm soreness? Sure. Serious complications? No evidence. Rare side effects? Same rate as unvaccinated people. Translation: social media invented the danger. Cochrane couldn’t find it. Lawsuits against HPV vaccines? Courts dismissed claims as “speculative inferences.” Translation: conspiracy theories don’t hold up under evidence. Meanwhile, cervical cancer kills 350,000 women every year. Mostly young women. Mostly preventable. We don’t need more fear. We need more vaccination. And yes - boys should get the vaccine too. HPV doesn’t only cause cancer in women. Vaccinating boys protects everyone. Some countries are on track to eliminate HPV cancers entirely. Others are falling behind because misinformation spreads faster than vaccines. That shouldn’t be our legacy. We already have the tool to end cervical cancer. Not reduce it. End it. The only thing standing in the way is fear. Science isn’t asking for blind trust. It’s showing its receipts. Stop sharing rumors. Start preventing cancer.

Australia just recorded zero cervical cancer cases in women under 25 - for the first time since records began in 1982. This is what happens when a country commits to HPV vaccination and screening. We protect our girls and save lives.

Stress-induced sympathetic hyperactivation drives hair follicle necrosis to trigger autoimmunity: @CellCellPress cell.com/cell/fulltext/…

Granzyme K+ CD8 T cells slow tauopathy progression by targeting microglia nature.com/articles/s4159…

It’s no secret that we do our best work when it's less like work and more like a joy. That’s what we have in mind for Woodstock Night Science. The idea is to have the most fun conference possible so that good ideas flow and we all get inspired. That's needed now more than ever!

Pyrolysis gas chromatography-mass spectrometry reveals the presence of micro- and nanoplastics in human kidney, liver, and brain tissue samples from 2016 and 2024, with higher proportions found in the brain nature.com/articles/s4159…

#WeekendRead! #LipidPower! Hugues &co show @NatureComms that lymphatic endothelial cells modify cholesterol into oxysterols, blocking PPARg in intratumor macrophages & monocytes, making them more inflammatory thus potentiating anti-tumor T cell responses!! nature.com/articles/s4146…

and here is another way of explaining immune contribution to brain physiology throughout life: x.com/Ali_MoussaSami…

And discuss how these routes are used for development and maintenance but become hijacked or modified in aging and pathology. Hope You enjoy it!

And it's out! The BIC lab presents our new perspective article on "Immune Control of Brain Physiology" - fresh off the press at @NatRevImmunol nature.com/articles/s4157… wonderful synergy @_marikovacs @Ali_MoussaSamir and twitterless Amaia Dominguez-Belloso.

@institutpasteur Congratulations!!!!

🙌🏅 Félicitations à Gérard Eberl, chercheur à l’Institut Pasteur, lauréat du prix 2024 de l’Académie Nationale de Médecine, pour l’excellence de ses travaux en lien avec l’analyse de l’impact du microbiote sur le système immunitaire. 👉 academie-medecine.fr/missions-et-st…

@PatriziLab @ccortical wow! congratulations!

Excited to share a new paper from our group. A shout-out to Tony Hill (@ccortical ) that spearheaded the first single cell atlas of choroid plexus tumors! Single-nucleus RNA-seq dissection of choroid plexus tumor cell heterogeneity | The EMBO Journal embopress.org/doi/full/10.10…

Our latest paper on neuronal resilience. The apoptotic pathway is activated as a transient pulse in neurons even with continuous apoptotic stimulus. Neurons prepare for survival even when they activate apoptotic signaling. Congrats Keeley and others!! nature.com/articles/s4141…

❇️ Ce 22 octobre, l’Institut illumine ses bâtiments en vert pour soutenir le syndrome Phelan-McDermid (PMS), un trouble génétique associé à un retard du développement et à l’autisme. Les recherches sur SHANK3 ouvrent la voie à des essais cliniques prometteurs. 💚 #ShineGreen

Corning now offers sterile tips that come in a paper container, thus generating less plastic waste!

Neuropeptide signalling orchestrates T cell differentiation @Nature nature.com/articles/s4158…