The B-HIVE Center

New paper in @PNASNews on the coarse-grained simulations explore the ways HIV-1 capsid cone approaches the nuclear pore complex and remains intact during the passage #HIV1capsid #NuclearPoreComplex #LatticeElasticity #CoarseGrainedMolecularDynamics @BHIVE_Center

Please join us in congratulating this year’s CDP Awardees! 👏And stay tuned for B-HIVE CDP RFAs next year if you missed the application window this time.

Ludovic Autin, PhD, Staff Scientist at CCSB @scrippsresearch. Dr. Autin will be constructing detailed atomic models of the HIV virion at various stages using their cellPACK ecosystem, leveraging data from cryo-EM/cryo-ET studies, including those from @RobDickLab.

We are excited to announce the 2024 Collaborative Development Program (CDP) Awardees. This year, the CDP will provide support for two innovative investigators to bring new, synergistic methodologies to the Center and be fully integrated in the B-HIVE community. Thread below 🧵:

2024 RFA is here! The B-HIVE Center is seeking creative researchers, early in their career and/or new to HIV research, to join us in studying the structural and dynamic viral-host interactions of HIV proteins and host factors. For more info, see hivecenter.net/collaborative-…

A few pictures from the West Coast Retrovirus Meeting--congratulations to Xin (Kristy) Wen for the poster award!

Anne X-Z Zhou discusses recent work from the Williamson and Millar laboratories, using mass photometry to explore the assembly of Gag protein on membranes. Take a look at: hivecenter.net/bhivehighlight…

Join us at UCRM this year!

Jerry Joe Harrison and Dario Passos discuss the structure of HIV-1 Pol Polyprotein in a new B-HIVE Structure Highlight--take a look at: hivecenter.net/bhivehighlight…

Registration is open for the 2023 NIAID HIV Structural Biology Meeting Monday, June 26th and Tuesday, June 27th at the NIH Natcher Conference Center in Bethesda, MD. Meeting Website: cvent.me/7zZ1MQ Register here: web.cvent.com/event/917cdd00…

Two postdoc positions in molecular virology and molecular cancer biology are available in my lab. Email your resume/CV to debrahimi@txbiomed.org. #HIV #Cancer #Bioinformatics #APOBEC #MolecularVirology #CancerGenomics

BHIVE members presented recent work at the 2023 CROI Conference: LENACAPAVIR DISRUPTS HIV-1 CORE INTEGRITY WHILE STABILIZING THE CAPSID LATTICE Chenglei Li, Ryan C. Burdick, Wei-Shau Hu, Vinay K. Pathak

📣Please RT!📣 The B-HIVE Center is seeking creative researchers, early in their career and/or new to HIV research, to join us in studying the structural and dynamic viral-host interactions of HIV proteins and host factors. For more information, see hivecenter.net/collaborative-…

"HIV-Infected Cell" shows a T-cell with integrated HIV-1 DNA (thin white lines at upper right) and viruses assembling and budding at the cell surface. Full-size files, hand drawn at a scale of 1 nm/pixel, are free for use at: hivecenter.net/resources/visu… and pdb101.rcsb.org/sci-art/goodse….

Join us for the 7th International Conference on Retroviral Integration, Jul 31 to Aug 4 2023, at University of Colorado in Boulder. Integration is the hallmark step of retroviral replication and integrase inhibitors are front-line therapies used to treat people living with HIV.

Putting the finishing touches on one of the most complex pictures I've ever done. It shows a cell infected with HIV-1, as part of outreach work for the @BHIVE_Center. Here's a little process animation--I'll post the full-size file and a description after I clean up a few things.

👏Please join us in congratulating this year’s CDP Awardees! 📣And stay tuned for B-HIVE CDP RFAs next year if you missed the application window this time.

Daniel Adu-Ampratwum, PhD, Research Scientist @OhioState Univ. College of Pharmacy @osu_pharmacy. This is Dr. Adu-Ampratwum’s 2nd year award to continue his work in the design and synthesis of small molecule probes to target HIV capsid during viral assembly and entry.

We are excited to announce the 2022 Collaborative Development Program (CDP) Awardees. This year, the CDP will provide support for 3 innovative investigators to bring new, synergistic methodologies to the Center and be fully integrated in the B-HIVE community. Thread below 🧵: