Lymphocyte Development & Epigenetic Memory Groups

40 posts

Lymphocyte Development & Epigenetic Memory Groups

@LymphDev

Lymphocyte Development and Epigenetic Memory Research Groups @MRC_LMS Tweets by lab members

انضم Temmuz 2020

125 يتبع224 المتابعون

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Lymphocyte Development & Epigenetic Memory Groups@LymphDev·31 Tem

We are on Twitter! Our @MRC_LMS research group, run by Professors Amanda Fisher and Matthias Merkenschlager, is based at @ImperialMed Hammersmith Campus. We study how #GeneExpression patterns are established, transmitted through #CellDivision and changed during #Development.

Lymphocyte Development & Epigenetic Memory Groups tweet media

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Lymphocyte Development & Epigenetic Memory Groups@LymphDev·30 Tem

Our latest study “Competition shapes the landscape of X-chromosome-linked genetic diversity” is now out in @NatureGenet

MRC Laboratory of Medical Sciences (LMS)@MRC_LMS

🧬DNA inherited from one parent is expressed more in some parts of the body, and the reverse in others. New study in @NatureGenet shows how competition between X chromosomes in females shapes who we are News here ➡ lms.mrc.ac.uk/just-like-your… Paper here ➡nature.com/articles/s4158…

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MRC Laboratory of Medical Sciences (LMS)@MRC_LMS·24 May

💡A living sensor to evaluate the impact of environment on gene expression & health. A new LMS @LymphDev study in @CommsBio uses the light of a firefly to illuminate cells, revealing how vulnerable our lungs are to external factors. Read more: lms.mrc.ac.uk/news/

MRC Laboratory of Medical Sciences (LMS) tweet media

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Nature Communications@NatureComms·24 Ağu

.@ediem_aljibury @LymphDev @DanielRueckert adapt neural networks to the replicate-based analysis of Hi-C data and find that it successfully discriminates technical noise from biological variation. @MRC_LMS @imperialcollege #BiotechNatureComms nature.com/articles/s4146…

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Lymphocyte Development & Epigenetic Memory Groups@LymphDev·18 Ağu

Happy to share our study in which we used Siamese neural networks to develop a #DeepLearning method for replicate-based analysis of chromosome conformation contacts, in collaboration with ⁦@DanielRueckert⁩, spearheaded by ⁦⁦@ediem_aljibury⁩ nature.com/articles/s4146…

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MRC Laboratory of Medical Sciences (LMS)@MRC_LMS·19 Nis

#New publication by Epigenetic Memory makes exciting advances in using new #Bioluminescent tools in #epigenetic silencing research. These tools could aid the development of #epidrug therapies for diseases such as #cancer. 👉ow.ly/t7Uh50NMKzM @LymphDev @A_M_Dimond @Nature

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Biomedical Picture of the Day BPoD@BPoD_s·6 Nis

Gene Team – Mouse model for specialised molecular screening therapeutic strategies for #Duchennemusculardystrophy. Video & research by Hannah Gleneadie & Beatriz Fernandez-Ruiz et al @LymphDev @MRC_LMS in @CommsBio. More on bpod.mrc.ac.uk/archive/2023/4… with @MRC_LMS & @DrJohnAnkers

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MRC Laboratory of Medical Sciences (LMS)@MRC_LMS·31 Mar

The #EpigeneticMemory group published in @CommsBio on a potential new therapeutic strategy for #DMD 🎉. Bioluminescent gene reporters were used to model #GeneExpression, and researchers found compounds that increase utrophin in developing muscle cells. 👉ow.ly/Xg8Z50NwWUK

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Beatriz.@beatrizfzr·3 Nis

Very excited to finally see our study out! We developed new models to study utrophin and dystrophin's gene expression patterns in vivo by bioluminescence and explored possible therapeutic options for Duchenne Muscular Dystrophy.

MRC Laboratory of Medical Sciences (LMS)@MRC_LMS

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Lymphocyte Development & Epigenetic Memory Groups@LymphDev·31 Mar

A wonderful weekend read from us! Our study "Endogenous #bioluminescent reporters reveal a sustained increase in #utrophin gene expression upon EZH2 and ERK1/2 inhibition" is now out in @CommsBio Paper: nature.com/articles/s4200… @MRC_LMS @ImperialMed Story👇 lms.mrc.ac.uk/new-breakthrou…

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ESC & iPSC News@ESC_iPSC_News·21 Mar

H3K9me3 is important for chromosome architecture and epigenetic memory during cell division. Drs. Amanda Fisher and Dounia Djeghloul's team showed that enzymes that catalyze H3K9 #methylation are retained on mitotic #chromosomes 🧬. @LymphDev @MRC_LMS go.nature.com/3TzUB38

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Lymphocyte Development & Epigenetic Memory Groups@LymphDev·21 Mar

We are happy to share that our study "Loss of H3K9 trimethylation alters chromosome compaction and transcription factor retention during mitosis" is now out in @NatureSMB lms.mrc.ac.uk/unlocking-the-… nature.com/articles/s4159… @MRC_LMS @ImperialMed

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Lymphocyte Development & Epigenetic Memory Groups@LymphDev·16 Ara

Our traditional Christmas dinner / secret Santa and once again a wonderful evening with Lymphocyte Development and Epigenetic Memory teams 🥳 @MRC_LMS @ImperialMed @imperialcollege

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Nature Communications@NatureComms·21 Eyl

Researchers @MRC_LMS @IreneYNadie @LymphDev show inducible genes and enhancers are regulated mainly by transcriptional burst frequency that this is coordinated in single cells and individual alleles and requires cohesin. go.nature.com/3LDYNek

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Irene Robles@IreneyNadie·16 Ağu

Thrilled to see my 5 years of work finally published. nature.com/articles/s4146…

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Hakan Bagci@hknbgc·22 Tem

Thé ⁦@LymphDev⁩ group is ready for ⁦@MRC_LMS⁩ rounders tournament! ⚾️

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Lymphocyte Development & Epigenetic Memory Groups أُعيد تغريده

Nature Communications@NatureComms·4 Tem

Researchers @LymphDev @MRC_LMS showed that a high-fat diet in mice can release silencing of the imprinted Dlk1 locus in subsequent generations via changes in microRNA expression. go.nature.com/3Ib8zCI

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Judith Haarhuis@JudithHaarhuis·24 Haz

What a wonderful week with the @LymphDev and the @dpanne1 labs! Great science, new insights and lots of fun (and exploring the hills by bike)!

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Hakan Bagci@hknbgc·24 Haz

And it’s a wrap! @LymphDev, Rowland and @dpanne1 joint lab retreat comes to an end with a visit to Grottes de Remouchamps. Great few days with this wonderful bunch- lots of science and fun (and Belgian beer)!

Spa, Belgium 🇧🇪 English

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Hakan Bagci@hknbgc·22 Haz

This week we, ⁦@LymphDev⁩, are in Spa, Belgium for a joint retreat with Daniel Panne (@dpanne1 ⁦@uniofleicester⁩) and Benjamin Rowland (@NKI_nl⁩) groups in this beautiful house

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Lymphocyte Development & Epigenetic Memory Groups@LymphDev·2 Mar

We are happy to announce that our research article entitled "Loss of H3K9 tri-methylation alters chromosome compaction and transcription factor retention during mitosis" is now out on bioRxiv: biorxiv.org/content/10.110… @MRC_LMS @ImperialMed

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اكتشف

@NatureGenet @CommsBio @ediem_aljibury @DanielRueckert @MRC_LMS @imperialcollege @A_M_Dimond @Nature