PearsonLab

Celebrating the retirement of my mentor and friend @PearsonRick He worked for @PeterMacRes 40% of his life and I worked with him 32% of my life! The best work comes when we work with people we like, trust &. respect. We celebrated @SVIResearch where he started as a PhD student

📢 @PeterMacCC say they are using techniques from astronomy and ecology to help cancer research 🌌🔬 #CancerResearch #ScienceAdvances scimex.org/newsfeed/peter…

Have spatial tissue data but not sure what methods or R packages to use for the analysis? Our paper describing SPIAT for spatial analysis and spaSim to simulate tissue spatial data is now out in Nature Communications! @PeterMacRes @PMPostdocs @PearsonLab1 nature.com/articles/s4146…

All exercise is beneficial but for cell health, train longer @LuigiFontanaMD @KeefeChan1 smh.com.au/lifestyle/heal…

I'm so grateful for having received an NHMRC Ideas grant to study cancer ecosystems in prostate cancer using spatial technologies and developing new methods. Looking forward to the years ahead! @PeterMacRes @PearsonLab1 @PMPostdocs @PCF_Science @gu_onc petermac.org/news/six-nhmrc…

Continuing the tradition of playing bad Santa and good times with my old lab ⁦@PearsonLab1⁩ in a joint Xmas lab function. Happy Xmas!

Congratulations to our two Honours students Sirui (Cathy) Weng and Yuxi Cao for presenting their final talks this week. Both have accomplished a lot this year and we are very proud of them! @PearsonRick @anna_t_g @JianKan60899540 @elaine_sanij @KeefeChan1

Our work using spatial analysis to investigate the tumour immune microenvironment of prostate cancers with DNA repair mutations is now out in @jitcancer -> jitc.bmj.com/content/10/6/e…

Let's talk about how 😴 can stop some cells forming cancers. Firstly, many cancers are driven by the inappropriate activation of molecules that control the growth of normal cells.

In this study, @PearsonLab1 showed that the enzyme cystathionine-beta-synthase (or CBS for short) is required to keep sleeping cells asleep rather than turning cancerous.

Thank you to @eLife for a constructive review process that has resulted in a stronger manuscript. An amazing effort by @PearsonLab1 @PeterMacRes @zhuhaoran1992 @KeefeChan1 @elaine_sanij @anna_t_g @PearsonRick @JianKan60899540 ! #senescence

Our study highlights the role of CBS in regulating AIS and raises the possibility that manipulating CBS can be a metabolic strategy to target PI3K/AKT-driven cancers. /10

We are delighted to share our latest work "Cystathionine-ß-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation" published in @eLife today! elifesciences.org/articles/71929 /1