COMETS

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Ali R. Zomorrodi@arzomorrodi·12 Eki

New version of COMETS to simulate #microbialCommunities in spatially heterogenous environments using #GEMs of #metabolism. Such a beautiful work from the lab of my former postdoctoral adviser @dsegre!!

Our comprehensive guide to #COMETS (Computation Of Microbial Ecosystems in Time and Space) is out at @NatureProtocols. Read at rdcu.be/czjo9. We hope you will find it useful for #modeling the dynamics of #metabolism in microbial communities. #dFBA #microbiomes. 1/6

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William Harcombe@HarcombeLab·12 Eki

Great to see the new version of COMETS published. It was really fun getting to collaborate with this team. @idouk, @metaboli3am, @JeremyMChacon, and Mike Quintin did some heavy lifting with lots of support from Korolev lab, @asanchez_lab, and @segrelab.

Our comprehensive guide to #COMETS (Computation Of Microbial Ecosystems in Time and Space) is out at @NatureProtocols. Read at rdcu.be/czjo9. We hope you will find it useful for #modeling the dynamics of #metabolism in microbial communities. #dFBA #microbiomes. 1/6

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Djordje Bajić@metaboli3am·12 Eki

Thrilled to finally see this out! What a privilege it has been working on this together with @segrelab, @HarcombeLab and Korolev lab. Looking forward to developing new functionalities, and to all the exciting new questions that @RunCOMETS is going to allow us explore!

Our comprehensive guide to #COMETS (Computation Of Microbial Ecosystems in Time and Space) is out at @NatureProtocols. Read at rdcu.be/czjo9. We hope you will find it useful for #modeling the dynamics of #metabolism in microbial communities. #dFBA #microbiomes. 1/6

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Alvaro Sanchez@asanchez_lab·11 Eki

Very excited to see this out & to explore all the possibilities this new version of COMETS will open. Massive congrats to the amazing @dsegre, @idouk @metaboli3am @JeremyMChacon & Mike Quintin & all other co-authors from BU & @HarcombeLab. Has been a privilege to work with them.

Our comprehensive guide to #COMETS (Computation Of Microbial Ecosystems in Time and Space) is out at @NatureProtocols. Read at rdcu.be/czjo9. We hope you will find it useful for #modeling the dynamics of #metabolism in microbial communities. #dFBA #microbiomes. 1/6

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segrelab_news@segrelab·11 Eki

#COMETS was made possible by funding from @doescience. Development of specific functionalities was enabled also by grants from @NIH, @NSF, @HFSP and others. 6/6

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segrelab_news@segrelab·11 Eki

We hope #COMETS will continue to grow as a collaborative tool with new biological modules and capabilities. Check @RunCOMETS for updates, gitter.im/segrelab/comets for feedback, questions and discussions, and let us know if you want to contribute! 5/6

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segrelab_news@segrelab·11 Eki

New #COMETS includes improved biophysics of biomass expansion, evolutionary dynamics, day-night cycles for photosynthesis, extracellular enzymes. Coded in #Java, but easy to run with #Matlab and #Python toolboxes. Compatible with #COBRA tools. Free at runcomets.org 4/6

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segrelab_news@segrelab·11 Eki

#COMETS enables computer simulations of multiple species interacting with the environment and each other through competition/exchange of metabolites. This is dictated by resource allocation in organisms, as a function of metabolic stoichiometry encoded in their genomes. 3/6

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segrelab_news@segrelab·11 Eki

Our comprehensive guide to #COMETS (Computation Of Microbial Ecosystems in Time and Space) is out at @NatureProtocols. Read at rdcu.be/czjo9. We hope you will find it useful for #modeling the dynamics of #metabolism in microbial communities. #dFBA #microbiomes. 1/6

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