Umut Sahin

382 posts

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Umut Sahin

Umut Sahin

@SahinLabSU

Scientist, principle investigator @sabanciu, studying SUMOylation in health and disease; @BrownUniversity, @MSKCancerCenter, @institutpasteur, @Inserm alum

Istanbul انضم Şubat 2020
712 يتبع1.2K المتابعون
Umut Sahin
Umut Sahin@SahinLabSU·
Looking forward to this fantastic event co-hosted by @sabanciu and the French Embassy.
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Roland Dunbrack 🏳️‍🌈 @rolanddunbrack.bsky.social
Talked to someone who failed to cite our preprint that showed an AlphaFold model with lots of experimental validation when he submitted cryo-EM paper of exact same sytem in Nature with no bio. data 6 months later. He said as a matter of policy "I don't cite preprints." Unethical.
Ruslan Rust@rust_ruslan

I currently have three papers in review at "high impact" journals. One of them has been sitting there for two years. In that time my daughter was born and learned how to walk, but apparently publishing a PDF was still not possible for me. For another one, after four months in review the editor told me they cannot find a second reviewer and asked me to suggest more reviewers. A third one sent me a message in 2026 saying the PDF I uploaded was larger than 10 MB and that I should please reupload everything to make the file smaller. All of this just to eventually pay between 7,000 and 12,000 USD per paper so someone can officially approve that the science we do is "legitimate". Reminder: not a single reviewer will be compensated here. I still don't understand how we as scientists can collectively be so smart when doing science and still tolerate a system like this when it comes to sharing our findings. We should move to preprints plus open review, whether human or AI, asap. So frustrated about it. I'd suggest sharing your work on bioRxiv or medRxiv, reading and reviewing preprints when you can, and highlighting good research, especially if it is still a preprint. Try platforms like ResearchHub (that pay for peer review) and experiment with AI based reviewers for faster feedback. Instead I read this as a proposed "revolutionary" measure:

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Umut Sahin
Umut Sahin@SahinLabSU·
Our new paper demonstrates for the first time the in vivo feasibility of PML-based therapeutic strategies for neurodegeneration. Focusing on ALS, we provide strong proof of concept evidence that inducing PML to clear disease-causing proteins is a promising therapeutic approach
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Venk Murthy MD PhD
Venk Murthy MD PhD@venkmurthy·
Sadly, the rate publication inflation is likely to get worse! The slicing of what should be a supplemental figure into entire separate papers, and then slicing again, and again is now standard practice It threatens scientific quality and actually may slow real progress
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Sabine Hossenfelder
Sabine Hossenfelder@skdh·
Two business school professors from the University of Technology in Sydney have sounded the alarm on the declining quality of academic literature in a new publication titled “The junkification of research”. Drawing parallels to the “enshittification” of online platforms, they argue that similar forces are now overwhelming scholarly publishing. The key drivers are threefold: 1) relentless “publish or perish” pressures in academia, 2) scientific publisher’s incentive to publish more to make more money, and 3) AI making paper production faster and easier. Taken together, they say, these drivers are a recipe for disaster. The authors call for a shift to not-for-profit models of scientific publishing and better evaluation systems. I strongly doubt either is going to happen. The problem is of course not new, and you all know that I have been drawing attention to this trend for more than a decade. It is interesting to see, however, that the awareness for the issue is increasing. Paper: Rhodes, C., & Linnenluecke, M. K., “The junkification of research” Organization (2025).
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Jason Locasale
Jason Locasale@LocasaleLab·
Science used to be about discovery. Now it’s about formatting PDFs correctly for a 9% chance of funding.
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Umut Sahin
Umut Sahin@SahinLabSU·
New paper out ! In this Viewpoint article, I explore a bold and provocative idea: that Cas9, the catalytic engine of the CRISPR gene editing platform, may also possess a previously unrecognized effector-like role in eukaryotes during bacterial infection febs.onlinelibrary.wiley.com/doi/full/10.11…
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Bilim Akademisi
Bilim Akademisi@BilimAkademisi·
Nejat F. Eczacıbaşı Tıp Ödülleri’nden üçü, BAGEP Ödül sahibi Ali Koşar, Umut Şahin ve Fatih İnci’ye verildi. 2013’ten beri genç akademisyenlere araştırma desteği sağlayan Bilim Akademisi olarak araştırmacılarımızı kutluyoruz. bilimakademisi.org/uc-bagepliye-e…
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Umut Sahin
Umut Sahin@SahinLabSU·
@ftm_guney The smoke-free zones around the buildings @sabanciu seem ineffective, most smokers completely ignore them.
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Ahmet Cingöz
Ahmet Cingöz@ahmetcingoz·
What is a PhD? “It is an award to an expert who has proven their scientific worth and not to someone who stayed in a tolerant group for long enough.” — "Bu, bilimsel değerini kanıtlamış bir uzmana verilen bir ödüldür, hoşgörülü bir grupta uzun süre kalmış birine verilen bir ödül değildir.”
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