Bo Wacker
805 posts

Bo Wacker
@bowacker
Father, Husband, Cyclist, Race Director, Coach, Bike Tours Commercial & Military background (FN, EU, OSCE & NATO) Marketing, Media, Communication, Sport, Events










Endurance athletes, please stop using NSAIDs. NSAID use is 30-80% depending on the race, especially #ultramarathon, despite warnings from scientists and medical experts on the risks. Mechanism of Action Through their anti-inflammatory effects, NSAIDs blunt prostaglandin production in the kidneys, in turn causing vasoconstriction and decreased blood flow. This increases kidney strain considerably. Kidney Strain When Racing This at a time when the renal system is already under strain from endurance exercise: In exertional rhabdomyolysis, damaged muscles leak myoglobin into the blood. It's filtered by the kidneys but can, in large quantities, obstruct the renal tubules, causing injury. Dehydration reduces blood volume, renal blood flow, and glomerular filtration rate (GFR). Electrolyte imbalances can impair the kidneys' ability to concentrate urine and maintain acid-base balance. Downstream Effects And not just the kidneys. The cardio-renal axis refers to the bidirectional relationship between the heart and kidneys. Dysfunction in one organ can lead to dysfunction in the other due to their shared regulatory pathways. So, kidney injury increases the risk of cardiopulmonary complications. NSAID use during racing considerably increases the risk of acute and maybe chronic renal and cardiopulmonary injury. Stop using NSAIDs. #endurance #sportsmedicne Links: pmc.ncbi.nlm.nih.gov/articles/PMC44… pubmed.ncbi.nlm.nih.gov/24650338/ pubmed.ncbi.nlm.nih.gov/35534373/

Russian stripped of London 2012 medal in Olympics’ ‘dirtiest race’ #Echobox=1732023154" target="_blank" rel="nofollow noopener">independent.co.uk/sport/olympics…










