Megadalton Solutions

Dr. Martin Jarrold and Dr. David Clemmer of @IUBChemistry at @IUCollege discuss their groundbreaking new technology of charge detection mass spectrometry, or CDMS.

Exciting work profile the interaction of Antibodies with #AAV #GeneTherapy

Our fabulous summer interns have travelled across The Pond from Indiana University to learn lots about native MS! They have been busy working hard in the lab and squeezing in all the touristy bits @IUBChemistry @KavliOxford @OxfordChemistry #TeamMassSpec

New technologies including charge-detection mass spectrometry, mass photometry, and nanoelectromechanical systems are allowing researchers to measure the mass of individual molecules, complexes, and particles. Read on to learn how these technologies work: fal.cn/3yPIR

Analysis of AAV-Extracted DNA by Charge Detection Mass Spectrometry Reveals Genome Truncations pubs.acs.org/doi/10.1021/ac…

Pleased to showcase the use of CDMS to characterize thermally driven AAV structures. tinyurl.com/mrxvczrh #AAV #GeneTherapy #bioprocessing

We are excited to be presenting today at #ASGCT2022. Come to Room 204 to see how we use CDMS to directly measure the mass of packaged DNA in AAV.

Two IU chemistry professors found a way to test the effectiveness of pharmaceuticals that could revolutionize the medical field. heraldtimesonline.com/story/news/loc…

An IU faculty startup has reached a deal with a major corporation to use their technology in equipment with applications to the development of new cell- and gene-based therapies. go.iu.edu/4kDQ

Analysis of Recombinant Adenovirus Vectors by Ion Trap Charge Detection Mass Spectrometry: Accurate Molecular Weight Measurements beyond 150 MDa #AC pubs.acs.org/doi/10.1021/ac…

Scientists use charge detection mass spectrometry to characterize the megadalton-sized antigens from classical multivalent vaccines directly from commercial formulations. pubs.acs.org/doi/10.1021/ac…

Still time to register for this virtual event on June 24th, in partnership with @Waters and @SelectScience. A lot of great talks on analytical methods and solutions for vaccine and therapeutic development. bit.ly/3gA8psk” #vaccines #vaccinedevelopment #virtualevent

#ASGCT21 Join us at 6:45 pm in the Downstream Process of Vector Manufacturing session #aav #genetherapy #adenovirus

New work from the Dragnea and M. Jarrold labs shows that co‐assembling brome mosaic virus coat proteins and nucleic acid oligomers generates unstable capsid structures with stoichiometries that differ from the icosahedral virion. loom.ly/tljQmOE

Thank you to everyone for making 2020 a success. We look forward to working with you in 2021!

Last chance to register for tomorrow's CDMS webinar! Can't make it? The webinar will be made available on-demand to those who register. tinyurl.com/y649jzck #ImmerseLab #WatersInnovation #genetherapy #aav #DNA

Don't forget to sign up for next week's webinar discussing state of the art CDMS technology and applications tinyurl.com/y649jzck #ImmerseLab #WatersInnovation #genetherapy #aav #DNA

Megadalton Solutions and Waters innovate together to extend Charge Detection Mass Spectrometry (CDMS) to the cell and gene therapy sectors prn.to/36Glomi #ImmerseLab #WatersInnovation #genetherapy #aav #iub