Ogün Adebali

1/n UV radiation disrupts genome integrity, but how does the 3D genome facilitate DNA damage response (DDR)? Our latest study with @vogulcankaya reveals how UV-induced genome reorganization enables efficient repair. 🌟🔬 🔗 nature.com/articles/s4146…

@AREWlker (wet experiments) and @berkayselcuk (analysis) are the co-first authors. @habibhobo performed MD simulations.

Take-home message: evolutionary information can do more than highlight “important residues.” It can help identify which residues encode subtype-specific behaviors, such as baseline trafficking/internalization.

🥳 We published our work co-led with @Hanyaloglu_Lab, in collaboration with @serdar_durdagi. doi.org/10.1016/j.isci… Differential conservation analysis identifies residues defining constitutive internalization in beta-adrenergic receptors @AREWlker, @berkayselcuk, @habibhobo

Getting prepared for my new course at home.

Two comments after my course: "After this course, I understand that I want to study bioinformatics" "The course made me make sure that I have zero interest in Comp Bio" Glad to see both. Knowing what you don't want to do is as important as knowing what you're interested in.

@hamptonism More important than ever!

Do you believe a PhD is worth it in the age of Artificial Intelligence?

Dear developers, in the era of AI, I urge you to specialize in a field. This field could be anything. Genetics is one of them. If you are interested, let's talk about where to start.

Have you already read this review? Conserved 3D genome reorganization during DNA repair @compGenomics @uzh_vetsuisse @fenssabanci @vogulcankaya hubs.la/Q03WR1jY0

Just realized that our work was highlighted - some time ago - by a popular science platform. Written by a real person, not AI 🥰 azolifesciences.com/news/20250324/…

I’m happy to co-author this review with our PhD candidate, @vogulcankaya! A big thanks to Drs Nägeli and Yancoskie for their lead. We’ll be sharing more updates from this team in the coming months. Stay tuned!

Brendo: an open resource for uniquely transcribed genes in brain endothelial cells biorxiv.org/content/10.110… #biorxiv_bioinfo

Terrible comparison. Think about internet availability when it was first released.

(2/n) Oct 20 at @itu1773 Öncelikli ve Yenilikçi Araştırmalar Çalıştayı Nov 19 at @BilkentUniv MBG Departmental Seminar Nov 21 at @METU_ODTU Departmental Seminar There might be a couple more, currently uncertain... Feel free to join.

After a year away on my sabbatical, I accepted every seminar invitation that I could. Here is the schedule: (1/n) Oct 4 at @itu1773 BioScenario Oct 14 at Istanbul Univ - Evolution Club Oct 17 at @kocuniversity MBG Departmental Seminar Oct 18 at @UniBogazici BUEC IEEE