James Zwierzynski

If this work is interesting to you, we're hiring for a Senior Scientist with post-doctoral experience and a background in RNA molecular biology or whole organ imaging and analysis to join our small, collaborative team! Apply here: careersearch.stanford.edu/jobs/basic-lif…

@EuphrosMD Thank you! It certainly plays an interesting role here - Günter Wagner's group has beautiful work that implicates Cxcl12 in the evolution of an invasive pregnancy that interests us for future work!: nature.com/articles/s4155…

@jameszsci Cxcl12 is the architect of placental geography. Without it, invasion loses its compass. That PAS parallel suggests an ancient boundary mechanism. Beautiful work.

Excited to share our preprint, reviving @kristyredhorse's interest in the placenta from her PhD ~20 years ago! We find using 3D imaging that the mouse placenta is far more invasive than previously thought. Furthermore, we find a surprise from our favorite chemokine CXCL12...🧵:

This work was a product of intense work by the three of us, and we are very excited to share it with everyone! Of course, a huge thank you goes out to our funding sources, and especially everyone who has given us feedback, advice, and comments along the way.

We were surprised by CXCR4-activated decidual cells in these mice, given the paucity of analysis of this receptor in these cells. However, beautiful work out this week in Nature shows a population of CXCR4+ decidual cells associated with blood vessels and pregnancy complications.

Nature research paper: Developmental organization of sensory and sympathetic ganglia go.nature.com/41GvsZm

What a beautiful paper! And everyone's favorite chemokine makes an appearance 🤓 cell.com/cell/fulltext/…

What a tour de force paper - everyone should read this one! congrats @MingxiaGu!

postdocs.yale.edu/posts/2025-12-… The Koh Lab is hiring!! Please reach out to join our newly established lab as a postgraduate associate! Come help us write the first exciting chapter of our (hopefully epic) saga! #CraniofacialBM #HSCniche #Vascularbiology #Immunology #YaleStemCellCenter