Annals of Internal Medicine: Clinical Cases

A new case report details severe, symptomatic hypercalcemia following antibiotic bead placement in a patient receiving #dialysis. This case highlights the importance of cautious bead use and vigilant postoperative monitoring in patients who receive dialysis. bit.ly/3OyWjnv

A previously healthy 37-year-old man presented with persistent nasal cellulitis unresponsive to antibiotics. After incision, drainage, and persistent antibiotic treatment, his condition worsened. Nasal biopsy revealed extranodal natural killer/T-cell lymphoma, nasal type (ENKTCL-NT), a rare and aggressive non-Hodgkin lymphoma whose presentation can be subtle and easily mistaken for more common conditions. Read the full text here: bit.ly/4cTnqBw @AHAScience #AHAJournals

A case report describes chronic eosinophilic pneumonia (CEP), also known as Carrington disease, as the initial manifestation of rheumatoid arthritis (RA) in a 28-year-old woman. While the cause of CEP in RA is unclear, this case highlights the need to consider CEP in RA in patients presenting with recurrent pneumonia-like symptoms with a history of or ongoing joint symptoms. bit.ly/4eCYtNc @AHAScience #AHAJournals

A new case report details a rare case of severe, isolated calcific pulmonary valve stenosis (PS) in an 86-year-old woman who presented to the hospital with syncopal episodes. This case emphasizes the importance of considering PS as a cause of syncope in older adults. bit.ly/4mQLjOT @AHAScience #AHAJournals

Kratom and 7-OH mitragynine use is increasing in the United States despite being largely unregulated. A new clinical reflection discusses what clinicians should know about kratom and its active compound, 7‑OH, including pharmacologic effects, potential risks, and clinical considerations. bit.ly/48jh3WV @AHAScience #AHAJournals

Read online for free: An Unrecognized Case of Glanzmann Thrombasthenia Associated With Gastrointestinal Bleeding bit.ly/47PM2tp @AHAScience #AHAJournals

One of the most popular Mini but Mighty sessions, “Turning an Interesting Clinical Case into a Publication,” drew a packed audience as Annals of Internal Medicine: Clinical Cases Editor-in-Chief Gustavo R. Heudebert, MD offered straightforward, practical tips for publishing clinical case reports. Learn more about submitting your case report to AIMCC here: bit.ly/4sAN6IZ #IM2026

Calcium pyrophosphate deposition disease (CPPD) typically involves the knees and wrists, but a new case report describes crystal‑proven CPPD of the sternoclavicular joint. Read the full text for free: bit.ly/4ekVSHw @RLWBowman @AHAScience #AHAJournals

‘Writing and Publishing Case Reports’ was a lively and informative session. Annals of Internal Medicine: Clinical Cases Associate Editor David J. Aizenberg, MD, FACP discussed the role of case reports in both science and education and described important components of a well-written #CaseReport. #IM2026

We're excited to be in San Francisco for @ACPIMPhysicians Internal Medicine Meeting 2026! Stop by to chat with our editors and staff and learn how you can publish your case report in Annals of Internal Medicine: Clinical Cases. #IM2026

A patient with smoldering multiple myeloma developed progressive corneal opacities initially thought to represent paraproteinemic keratopathy (PK). Histopathologic analysis revealed lipid keratopathy (LK), preventing unnecessary treatment and changing the management of the patient. This case illustrates the diagnostic challenge of distinguishing LK from PK in patients with monoclonal gammopathies. bit.ly/4tzHzDn @AHAScience #AHAJournals

A new case report describing a drug–drug interaction between rifampin and glucocorticosteroids in a patient with lupus underscores the importance of conducting a thorough evaluation of medications for any potential drug–drug interactions in immunosuppressed individuals. bit.ly/3QcSvbJ @AHAScience #AHAJournals

Authors from @UPMC describe an unusual case of a patient with obstructive sleep apnea who developed symptomatic hypoxemia with methemoglobin levels less than 10%, challenging traditional diagnostic thresholds. Read the full text for free: bit.ly/4bZy4aP @AHAScience #AHAJournals

A new case report reveals the dangers of using unregulated dietary supplements. A 24-year-old woman developed gastrointestinal upset and cardiac arrhythmia after taking tejocote root, a common herbal supplement used for weight loss and to induce bowel movements. This case highlights why clinicians should maintain a high index of suspicion when assessing patients with unexplained cardiotoxic symptoms and consider dietary supplement histories. bit.ly/4ck8Naj @AHAScience #AHAJournals

Editors from Annals of Internal Medicine and Annals of Internal Medicine: Clinical Cases @AnnalsofIMCC will be in San Francisco next week for #IM2026. Follow along for updates, highlights, and breaking news from the meeting.

Retatrutide, a triple-hormone receptor agonist, is hypothesized to have potentially greater efficacy than other #GLP1 medications; however, it does not have FDA approval and is currently in Phase 3 clinical trials. A new case report describes a patient who was hospitalized for severe diarrhea and acute kidney injury after self‑administration of #retatrutide that was purchased online. This case highlights safety concerns surrounding unregulated access to emerging weight‑loss therapies and the need for stronger oversight. bit.ly/3O7xT4a @AHAScience #AHAJournals

A new case report details a patient initially diagnosed with preeclampsia whose continued hypertension and proteinuria revealed steroid‑refractory minimal change disease. This case illustrates why persistent postpartum #hypertension and proteinuria should prompt clinicians to look beyond preeclampsia. bit.ly/41m6BKo @AHAScience #AHAJournals

Renal subcapsular hematoma is a rare but serious complication of kidney transplant biopsy, and it may be reversible with timely intervention. A new case series describes four post-biopsy cases and highlights the critical role of early recognition in preserving graft function. bit.ly/4bYZ22g @AHAScience #AHAJournals

Infectious aortitis is a rare and potentially fatal condition that can arise from gastrointestinal infections. A case series presents two cases of aortitis caused by gastrointestinal bacteria and reviews the management of this complex syndrome, highlighting signs that may support earlier diagnosis and treatment. Read now: bit.ly/4c6rSMW @AHAScience #AHAJournals

DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) is a severe hypersensitivity syndrome with multiorgan involvement. A new case report illustrates a rare, severe DRESS phenotype with simultaneous rhabdomyolysis and probable myocarditis. Read the full text for free: bit.ly/41fyiEy @AHAScience #AHAJournals