Archiv der Pharmazie

The Georg lab @gunda_i is reporting selective retinoic acid receptor alpha antagonist ER-50891 and related analogs for male contraception. @UMN_MedChem @Arch_Pharm @Wiley_Chemistry onlinelibrary.wiley.com/doi/10.1002/ar…

The Koch lab @WWU_Muenster is introducing to artificial intelligence and deep learning using interactive electronic programming notebooks in @Arch_Pharm. @Wiley_Chemistry onlinelibrary.wiley.com/doi/10.1002/ar…

Preventing brain damage and dysfunction after traumatic brain injury using potassium channel openers could become clinical practice if nontoxic analogs of retigabine could be found. Wurm et al. shed some light on the way to go.@Arch_Pharm @Wiley_Chemistry onlinelibrary.wiley.com/doi/10.1002/ar…

We are looking forward to the upcoming DPhG conference in Marburg @Uni_MR. And right at the beginning tomorrow, Tuesday, our editor-in-chief @ProfAndreasLink sums up the role of our journal @Arch_Pharm in the 21st century. Come in large numbers! @Wiley_Chemistry

Working together with my alma mater group 👩🏻‍🔬 from @UNSbahiablanca. Interesting first multidisciplinary approach for TADDOL derivatives. @Arch_Pharm @CosRoxy @nitinunimi @yorandredu @prasher_sharma @MandolesiSandra @Kam_Dua @FQuimica_UC @iibm_uc @UTalca @CBIB_UNAB @ucatolica

A new class of 1,4-Dihydropyridinebutyrolactone-derived ring-opened ester and amide analogs from the Georg lab @gunda_i to target BET bromodomains were just recently published in @Arch_Pharm. @UMN_MedChem @Wiley_Chemistry onlinelibrary.wiley.com/doi/10.1002/ar…

The Wende lab has published physical cold plasma for controllable prodrug activation in @Arch_Pharm: First exploratory example for a prodrug release triggered by tissue-compatible cold plasma in vitro. @Wiley_Chemistry onlinelibrary.wiley.com/doi/10.1002/ar…

Doppelte Auszeichnung für Dr. Steffen Pockes: GDCh-Innovationspreis 2022 und Adjunct Professorship für Pharmazeuten der Universität Regensburg. bit.ly/3LGj4OV

Congratulations to the #FiMC2022 Innovation Prize winners, Dr. Steffen Pockes @SteffenPockes and Dr. Oliver Thorn-Seshold @ThornSesholdLab! #medchem #chembio #pharma #drugdiscovery #medchemtalents #euromedchemtalents @YoungSciNet @EuroMedChem

The Wünsch lab has combined pharmacophores of two potent NMDA receptor antagonists to design oxazolobenzazepines @Arch_Pharm. These negative allosteric modulators of GluN2B-NMDA receptors may be useful in neurodegenerative disorders. @Wiley_Chemistry onlinelibrary.wiley.com/doi/10.1002/ar…

Jürg Zimmermann's 1996 report on selective kinase inhibitors in @Arch_Pharm is cited in @NatRevDrugDisc to have paved the way to identify and optimize synthetic small-molecule kinase inhibitors like imatinib. #AdP200 @Wiley_Chemistry onlinelibrary.wiley.com/doi/10.1002/ar…

Flashback: @Arch_Pharm ahead of @angew_chem on paullones: In 1992 the first report on the synthesis of indolo[3,2-d][1]benzazepines (dubbed paullones) by C. Kunick appeared shortly before the same heterocyclic system was reported by A. P. Kozikowski. #AdP200 @Wiley_Chemistry

Glad to have latest publication @Wiley @Arch_Pharm. lnkd.in/dG3gNmqA

The "Archiv der Pharmazie" @Arch_Pharm is turning 200 and we want to celebrate it with you. Below is the link to the invitation to our GPCR Special Collection served by @SteffenPockes as a guest editor. There is no submission deadline. @Wiley_Chemistry onlinelibrary.wiley.com/doi/toc/10.100…

Laura Schäkel et al. from @Mueller_AG @UniBonn have recently published 2-substituted thienotetrahydropyridine derivatives as allosteric ectonucleotidase inhibitors with improved selectivity profile in @Arch_Pharm. onlinelibrary.wiley.com/doi/10.1002/ar…

Check out our new publication of 2‐Substituted thienotetrahydropyridine derivatives: Allosteric ectonucleotidase inhibitors onlinelibrary.wiley.com/doi/10.1002/ar…

The Bracher group @LMU_Muenchen identified, by means of chemical synthesis and crystal structure analysis, the active stereoisomer of the TRPML1 inhibitor ML-SI3. This small molecule is an important tool to modulate this potential drug target @Arch_Pharm. onlinelibrary.wiley.com/doi/10.1002/ar…

Another big #GPCR meeting 🤩 Looking forward to present our data from @schulte_lab on using conformational receptor biosensors to study #Frizzled activation & signalling!

Thorough 2D NMR characterization of 1-oxo-1H-phenalene derivatives led to structure corrections and nanomolar inhibitors of BCL-2. Study and guidelines for proper structure determination in @Arch_Pharm were conducted by @IzidorSosic @c_steinebach @UniBonn. onlinelibrary.wiley.com/doi/10.1002/ar…

A colorful season is coming up 🍂🍁When chlorophyll is degraded in autumn, #phyllobilin levels rise! Curious to know more? A review in @Arch_Pharm by @PhylloLab gives an extensive overview of current knowledge on structures, occurrence, and #bioactivities. onlinelibrary.wiley.com/doi/10.1002/ar…