Benoit Dehapiot

Very happy to share the first article from my postdoc work in the Tomancak lab! biorxiv.org/content/10.110…. We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)

We are building a new bioimage analysis platform at the University of Bern! To setup and develop the platform we are hiring for three years an IT specialist and a Bioimage Analyst. All the infos here: ohws.prospective.ch/public/v1/jobs… and ohws.prospective.ch/public/v1/jobs…

Huge update to Convpaint, and preprint out on bioRxiv! We develop a pixel classifier similar to Ilastik, but built for napari & with technical improvements. Now even works on animals! 1/10

1/n We are very pleased to see our study on Wnt spreading in C. elegans embryos published in @CurrentBiology cell.com/current-biolog… . The outcome of an exciting collaboration between Vincent Bertrand's team and our team. A short thread on our main results!

10 days left to apply for #ZIDAS2024! This year in Zurich 😎

PatternJ: test our new tool to easily quantify periodic patterns inside and outside of #muscle #sarcomere even in #neuron - no computing knowledge needed. Easy installation in @FijiSc; developed by @PierreMangeol @IBDMmarseille @centuri_ls @univAMU_Europe biorxiv.org/content/10.110…

Please RT! Welcoming applicants with applied math/CS background for a PhD project with @ClaudioCollinet. Exploiting large language model of intracellular dynamics to decipher how thousands of flux events shape cells and organs. Apply until Feb 15th at t.ly/AIWld

Please RT! Welcoming applications for a PhD project with @PhilippeRoudot in the framework of the @centuri_ls PhD program. The project will focus on collective endocytic dynamics and their role in cell and tissue morphogenesis. Apply until Feb 15th at t.ly/AIWld

The BioVisionCenter is recruiting 🔥🔥🔥 We are hiring a Research Software Engineer, description below. Come work with us in Zurich and contribute to making bioimage analysis at scale accessible to all! If you have any questions reach out to me. jobs.uzh.ch/offene-stellen…

Our new data-driven mathematical model of sarcomere assembly is now out. All the math was done by our fantastic collaborators in Dresden @friedrich_group @PoLDresden @IBDMmarseille @ClaraMSidor @BDehapiot journals.aps.org/prxlife/pdf/10…

🏋️‍How to build muscle? Our new paper proposes a mechanism for the self-assembly of sarcomeres, the microscopic contractile units of muscle cells, combining experiments by @SchnorrerL lab @univamu & theory by @friedrich_group @PoLDresden @TUdresden_de 🧵 journals.aps.org/prxlife/abstra…

Congratulations to the 2 collaborating heroes of this work, @ClaudioCollinet and @AnaisBailles who discovered originally this self-organized morphogenetic wave in Drosophila, and delved deeper to reveal the underlying mechanochemical underpinnings. 👋👋👋 cell.com/developmental-…

It’s out! Learn how a self-organized wave of adhesion, contractility and de-adhesion is mechanically regulated at the cellular scale. authors.elsevier.com/sd/article/S15…

Another paper submitted! Here we show how synergy and coincidence detection of cytoskeleton and membrane components drives actomyosin activity at the right place during tube morphogenesis. @GhislainGillard, well done! @CellBiol_MRCLMB biorxiv.org/cgi/content/sh…

It's official! I will be joining the Living Systems Institute @LSI_Exeter in February 2024. Funded by a @wellcometrust Career Development Award, my team will investigate the biophysics of basement membranes during morphogenesis. Stay tuned for open positions! #newPI

Our November cover shows a confocal image (z-compression) of a fertilized mouse oocyte stained for #chromatin (magenta), F-#actin (red), and activated #myosin II (green). From Bourdais, @BDehapiot & Halet (bit.ly/3QquOJo) Read our November issue: bit.ly/49ohP3U

Spotlight from @Taka2326I, @TakashiAkeraLab & @ProfMOlson: Bourdais et al. (bit.ly/3qSnrBO) have discovered that MRCKβ activates cortial #myosin II rings to facilitate both spindle rotation in the egg and paternal nucleus migration in the zygote. bit.ly/3S1la2l

How do cells self-organize to set up the body axes? Together with the team of Matthias Merkel @MatthiasMerkel1, we address this question here: biorxiv.org/content/10.110…

Now online at @eLife in final form: the opus magnus by @ArturRuppel93 and Dennis Wörthmüller on optogenetic activation and force propagation in cell doublets. Check out the online version with its many cool animations at doi.org/10.7554/eLife.…