Gabriella Chua

One of my favorite studies to come out of the Liu and Alushin labs. Check it out 🚖🚙

Huge congratulations to the recipients of the 2026 Weintraub Award! These twelve exceptional graduate students exemplify the bold, creative, and pioneering spirit embodied by Dr. Hal Weintraub. fredhutch.org/en/news/releas…

Very excited to share our latest preprint, where we visualize the impact of force on the catch bonding actin crosslinker α-actinin-4. Led by @alfredcchin, a great collaboration with Glen Hocky's lab. biorxiv.org/content/10.648…

Nucleosome spacing regulates linker methylation by DNMT3A2/3B3 dlvr.it/TRL46G

Now online! A non-catalytic role for RFC in PCNA-mediated processive DNA synthesis dlvr.it/TQgqVG

A study in @CellCellPress from Shixin Liu (@InLiuOfBulkExps) and Michael O’Donnell finds that a protein once thought to simply help load a factor necessary for the copying of DNA actually plays a key role in ensuring fast and reliable replication: bit.ly/4qOodK1

Check out our paper @CellCellPress where we visualized the interplay between two key DNA replication factors PCNA & RFC and found an unexpected non-catalytic role of RFC in stabilizing PCNA’s interaction with DNA polymerase and enabling efficient synthesis cell.com/cell/fulltext/…

Our work on single-molecule visualization of mammalian transcription elongation is online @NatureSMB today! Check out the open-access paper rdcu.be/eR257 to see how Pol II acts as a multi-speed machine🚗We are thankful for our collaborators @RockefellerUniv @FudanUniv🙏

Vostal et al @KapoorLab_RU @RockefellerUniv report two structures of complexes formed by VCP, an unfoldase, & VCPIP1, a deubiquitinase, & suggest that VCPIP1 is poised to cleave #ubiquitin from protein substrates that translocate through VCP’s central pore hubs.la/Q03bV3G00

Some happy news. Pleased to see our paper showing how afadin strengthens cytoskeletal engagement by the cadherin-catenin cell adhesion complex out in @ScienceAdvances : bit.ly/3EFpD6h

Scientists in the @Alushin_Lab have figured out how cells build a structure that lets them migrate. Unpacking these “finger-like” protein bundles that protrude from cells may lead to novel treatments for metastasis. #RockefellerScience bit.ly/3PKErmA

Very happy to share our new review in @MolecularCell covering nucleic acid recognition and effector mechanisms for various prokaryotic immune systems! Was a great experience creating this with @MarraffiniLab! cell.com/molecular-cell…

Using the @LUMICKS C-Trap, the lab of @InLiuOfBulkExps provided unprecedented, real-time insights into the binding behavior of MeCP2, a protein linked to Rett syndrome, across methylated and unmethylated DNA and nucleosomes. lumicks.com/revealing-mecp…

Absolutely thrilled to share our new study, co-led by @PujaMajumder91 and myself, now online in @CellCellPress! Here, we characterize a CRISPR-associated adenosine deaminase, Cad1. Incredibly grateful for @MarraffiniLab making it possible. Synopsis below: cell.com/cell/fulltext/…

@science_SRH @LUMICKS_nl @matt_schaich @KaceyMersch Was great hanging out!😊

@Q_M_Smith @TPCB_NYC Thank you Quentin!!😁

@TPCB_NYC @BadAtCloning Congrats Gabriella!🥳

We are delighted to announce that Gabriella Chua (@BadAtCloning) has been awarded the 2024 TPCB Student Service Award for her outstanding commitment to scientific outreach, peer mentoring, and training. Congratulations Gabriella! linkedin.com/feed/update/ur…

Really honored to receive this award🤍😊 I was initially drawn to @TPCB_NYC for my graduate studies because the students were not just scientists; they were also leaders, advocates, & teachers fiercely focused on both science and society. Grateful!

@science_SRH @TPCB_NYC Thank you Sarah!!😊

Congratulations to Christian Baca @ChristianF_Baca in the Marraffini lab on being recognized by the Max Birnstiel Foundation and Research Institute of Molecular Pathology @IMPvienna with an Honourable Mention for the 2024 International Birnstiel Awards! linkedin.com/posts/tpcb_chr…

Want to introduce kids to the biophysics of DNA? Make candy models!! 🍬🍭🧬 Not only do they learn about its chemical sequence but also its physical features- bendability, stretch & twist- that are highly relevant to biology. Congrats to @rockedu_ on another 🔥 Science Saturday!