Baron Chanda

351 posts

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Baron Chanda

Baron Chanda

@ChandaLab06

Ion Channel Biophysicist. Loves greasy proteins. Fluorescence spectroscopy, Single molecule dynamics, Electrophysiology, Thermodynamics.

St. Louis, MO, USA Beigetreten Ocak 2019
301 Folgt1.4K Follower
Baron Chanda retweetet
Society of General Physiologists
Society of General Physiologists@sgpweb·
Announcing the second round of 2025 SGP Rising Star Travel Awards for students and postdocs. The $500 awards can be used for meetings held up to 1 year from notification. Apply today! Deadline: 31 December 2025 sgpweb.org/awards/risings…
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BaoLab
BaoLab@HuanBao4·
Our DeFrND approach is finally published. A simple trick to isolate membrane proteins with native lipids for structural and functional characterization. doi.org/10.1038/s41467…
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Baron Chanda retweetet
Society of General Physiologists
Society of General Physiologists@sgpweb·
SGP congratulates Dr. Huanghe Yang on receiving the 2025 Paul F. Cranefield Award for his outstanding paper, “Niclosamide potentiates TMEM16A and induces vasoconstriction” doi.org/10.1085/jgp.20…
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Baron Chanda retweetet
Society of General Physiologists
Society of General Physiologists@sgpweb·
SGP congratulates Dr. Man Si on receiving the 2025 Cranefield Postdoctoral Fellow Award for her outstanding paper, “Epilepsy-associated Kv1.1 channel subunits regulate intrinsic cardiac pacemaking in mice” doi.org/10.1085/jgp.20…
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Baron Chanda retweetet
Society of General Physiologists
Society of General Physiologists@sgpweb·
SGP congratulates Dr. Rachael Lucero on receiving the 2025 Cranefield Student Award for her outstanding paper, “Transport of metformin metabolites by guanidinium exporters of the small multidrug resistance family” doi.org/10.1085/jgp.20…
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Baron Chanda
Baron Chanda@ChandaLab06·
2) This work not only advances our understanding of HCN channel modulation but also lays the groundwork for developing isoform-specific analogs of propofol as targeted analgesics. A huge thank you to the talented team of collaborators. @AlexEversLab @veburts @johncowgill11
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Baron Chanda
Baron Chanda@ChandaLab06·
1) Excited to share our latest research uncovering a novel conformation-specific binding site for propofol in the voltage sensor domain (VSD) of HCN1 ion channels. science.org/doi/10.1126/sc…
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BaoLab
BaoLab@HuanBao4·
Happy to introduce DeFrND: designer peptide scaffolds to enable detergent-free reconstitution of membrane proteins with native lipids into nanodiscs for biochemical and structural studies. Let me know if you would like to try it. biorxiv.org/content/10.110…
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Baron Chanda
Baron Chanda@ChandaLab06·
Fortunate to live in a country that understood this more than anyone else...
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Baron Chanda
Baron Chanda@ChandaLab06·
Jon Lorsch's blog post: “One major barrier to entry into new markets is the requirement to see the future with clarity. It has been said that to foretell the future, one has to invent it. To be able to invent the future is the dividend that basic research pays.” Wong 1996
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Baron Chanda
Baron Chanda@ChandaLab06·
@DelemotteLab Indeed it was! The only thing missing from the video is the thunderous ovation at the end…
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Baron Chanda
Baron Chanda@ChandaLab06·
One of the unforgettable moments at the 2024 Ion Channels GRC was the closing lecture by Fred Sigworth. If you missed it, here it is.. youtu.be/db1afWzokOU?si…
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YouTube
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Baron Chanda
Baron Chanda@ChandaLab06·
Structures of channels in Open conformation are rare. Thrilled to share our latest manuscript.. Structural basis for hyperpolarization-dependent opening of human HCN1 channel disq.us/t/4p78xec
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Baron Chanda
Baron Chanda@ChandaLab06·
@Ella_Maru Gating is slow but we are not die of it is due to this transition.
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Ella Marushchenko
Ella Marushchenko@Ella_Maru·
@ChandaLab06 Congrats, Baron! Does the helix-coil transition impact the gating kinetics of the HCN1 channel?
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Entdecken

@AlexEversLab @veburts @johncowgill11 @RachelleGaudet @MarmolJosefina @Ella_Maru @elonmusk @BarackObama