Chapman Lab

Our most recent publication on anti-amyloid chaperone protein CsgC is out now! Special thanks to Sarabella for the JBC cover design which perfectly captures this work. Check it out here: jbc.org/article/S0021-…

I'm so fortunate to have great mentors who are superb human beings. Thanks to @mattchapman22 for a wonderful evening. It was great to catch up with @Chapman_Lab. Thanks to @caglatukel for this opportunity!!

Cell Surface-localized CsgF Condensate is a Gatekeeper in Bacterial Curli Subunit Secretion biorxiv.org/cgi/content/sh… #bioRxiv

I’m happy to announce that I successfully defended my Dissertation on Monday. Thank you to everyone who joined us at the defense, we had a packed house! And of course, thank you to everyone in the @Chapman_Lab for helping me finish this life goal. On to my next challenge!

I'm happy to announce that I've been awarded a Rackham Predoctoral Fellowship! Thank you to @umichgradschool! Also, big thanks to the members of @Chapman_Lab and @UMChemBio who have helped me get this far in my graduate studies. #UMChembio chembio.umich.edu/anthony-balist…

The second publication this year for our graduate student @Abalist_chembio! He and Emily were able to put together a great review arguing for the importance of functional amyloids in cellular biology. Give it a read and let us know what you think! mdpi.com/918144

Cryo-EM structure of the nonameric CsgG-CsgF complex and its implications for controlling curli biogenesis in Enterobacteriaceae. @PLOSBiology

@StallingsLab @HultgrenLab @Chapman_Lab @PeONor @KimInSingapore @BacterialTalk @BackvallJEB_grp @BergstromSven @GlobischLab @LwkMoodie @UAC_UU @Ucmr_sweden

First manuscript to leave the "Ant Farm", led by graduate student Anthony (Antz) @Abalist_chembio and highschool students Soorya and Ethan (now college bound). All of our papers are awesome, but we're particularly proud of this work frontiersin.org/articles/10.33…

#Covid_19 #StrongerTogether #research

What we learn from this is to not be too attached to any one answer early on that paints us into a corner. More information makes our answers better. It is on us all to think critically about new information and to ask the right questions.

The news cycle with Covid-19 is confusing largely because it showcases how messy research is.

Overtaken by stress granules. Still pulling for you @CellfOrganized #carboxysomes

Representing for our neighbor lab, @CellfOrganized

It's an honor to be part of STC Talmudic questions alongside other powerhouses of the amyloid field!

Urinary tract infections: microbial pathogenesis, host–pathogen interactions and new treatment strategies Klein and Hultgren discuss how novel insights may guide the development of antibiotic-sparing therapeutics @HultgrenLab @Roger__Klein nature.com/articles/s4157…

So proud of this paper and all the hard work that went into this story. Bacterial curli fibers produced in the gut can accelerate alpha-syn aggregation in the brains of mice @Jain_Lab elifesciences.org/articles/53111

Surprisingly on time! Wow! First time for everything at the #chapmanlabsymposium