David Casero

Why should you care about an indirect cost?, by @dr_kkjetelina open.substack.com/pub/yourlocale…

Research Associate Club at @IBDCedarsSinai, led by Dr. Rivkah Gonsky, empowers young investigators through mentorship & learning. These rising stars are shaping the future of IBD research. Kudos to Dr. Gonsky & IBDI for inspiring the next generation of scientists! #IBDResearch

New #JITC article: GrB-Fc-KS49, an anti-EMP2 granzyme B fusion protein therapeutic alters immune cell infiltration and suppresses breast cancer growth bit.ly/4iRun8l @DC_Genomics

@EdBarnesMD @doc_ibd @ShermanPrize Looking great up there Dermot, congratulations!!

Congratulations to @doc_ibd on winning the @ShermanPrize. His commitment to improving our understanding of #IBD as a clinician scientist and his call to public service should push us all forward. #AIBD2024

That's a wrap! The tribute film for @doc_ibd will premiere during his Prize presentation at @IBDConference #AIBD on Dec. 10. Learn more about his accomplishments at ShermanPrize.org @IBDCedarsSinai @tharitunians @CedarsSinai @STarganIBD

@Jonathansegal85 My Spanish friends, how can anyone vote far-right, racist VOX party? My French friends, how can anyone vote racist LePen? My Italian friends, how can anyone vote populist Meloni? My Austrian friends, how can anyone vote pro-Russian Freedom Party?. Unfortunately, this is deep

My American friends what am I missing? How can anyone vote trump? I really really don’t understand it.

@J_my_sci Agreed. But we can't keep re-analyzing data forever (or can we?). So in the meantime: read the methods, then re-read the methods (and metadata), then question the methods. Only after this, it is worth reading the paper. Same goes as editor/reviewer

@StevenSalzberg1 As before, I'm afraid we will load the gtf files to find a majority of predictions that look plain wrong and noisy. So yes, how transcripts are predicted and how methods handle sources of misannotations are crucial. Otherwise, fancy but a waste of end-user time

The importance of peer-reviewed bioinformatics methods: a short rant about a recent paper by some leading scientists in my field. Most scientists would agree that well-engineered computational methods are critically important in genomics... 1/8

@ItaiYanai it's called hypothesis generation, right? ncbi.nlm.nih.gov/pmc/articles/P…

Shame on him, shame on collaborators and publishers that looked the other way. They can now retract the papers, the damage is done: this guy accumulated influence and power, junior scientists were for years forced to perpetuate this, their ethics and careers degraded

Spanish university head accused of inflating citations to his own work | Science | AAAS science.org/content/articl…

🌟Explore how #AI is transforming medicine at the inaugural Biomedical AI Symposium on Dec 4th! I'm excited to co-direct this event featuring brilliant speakers like @SumeetSChugh @MelissaWongMD & @moorejh from #CedarsSinai. Don't miss out! Register today: ctsi.ucla.edu/news/biomedica…

Congratulations 2024 Sherman Prize Recipient @doc_ibd, @IBDCedarsSinai @CedarsSinai. Dr. McGovern has dedicated his career to advancing our understanding of #IBD genetics & delivering personalized medicine to patients. Read his story: ShermanPrize.org

Congrats Dermot!! Well deserved and long overdue. I'll save the advice on how to celebrate for those who need it (you don't).

@merenbey wishing you a great day!

@DC_Genomics I thought about this all night, and I deeply appreciated the point you've made, David. Thank you.

Today I learned that my father died a few days ago. He was an excellent person, but a terrible father. I tried very hard to forget about him growing up and I had zero emotions to this news as I always hoped. Life is short. Embrace your family and be great fathers to your kids.

@anaconesa Wouldn't blame reviewer 3. Would blame the program manager recruiting/assigning reviewers not appropriate for the grant. More so, for rarely setting up fund mechanisms focused on comp. methods development, makes it much more difficult for developers to get the message through.

Reading the reviews of a rejected proposal makes my blood boil. R3 states that the project doesn't develop a new methodology but "only" novel bioinformatics methods. How long will this disregard for computational research continue? Try to do your sequencing data analysis by hand!

@lpachter Things sometimes don't age well, that includes papers...

I've checked this paper out, as instructed. I was also interested in the main result for personal reasons: I'm 51 years old. Is it true that I've just gone through a major change? And that another one awaits me in just a few years? Some comments on the paper in this thread 1/🧵

Congrats to Kai Li @zachlee_2008, David Underhill et al. to their Nature paper. rdcu.be/dKqo4 New technique to study microbe-interacting entities in phagosomes discovered PD-L1, one of the most successful antitumor immunotherapy targets, as fungal-binding receptor.