David_Shiers

5.4K posts

David_Shiers

David_Shiers

@Davidiris1

Honorary reader in early psychosis Manchester Uni. Former GP and joint lead on UK EI in Psychosis Programme (2004-10); just my views

UK Beigetreten Haziran 2013
1.1K Folgt1.8K Follower
David_Shiers retweetet
Aoife Carolan
Aoife Carolan@carolanaoife·
Our guideline for the use of metformin to prevent antipsychotic-induced weight gain has just been published in Schizophrenia Bulletin. Read the full paper here: academic.oup.com/schizophreniab… A 🧵of the key points
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Aoife Carolan
Aoife Carolan@carolanaoife·
This is the first guideline produced by the PROGRESS research group. Lead by @BNODonoghue and funded by @hrbireland
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Aoife Carolan
Aoife Carolan@carolanaoife·
The one-page algorithm also lists important prescribing information including dosing instructions, possible side effects and monitoring recommendations
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Aoife Carolan
Aoife Carolan@carolanaoife·
We also recommend more intensive treatment if the person is overweight or obese. That is, to start a GLP-1 agonist if the person meets the criteria according to the license if these medicines are available
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Aoife Carolan
Aoife Carolan@carolanaoife·
3 core recommendations: 1: Co-commence metformin with high-risk antipsychotics (olanzapine,clozapine) 2: Co-commence metformin with medium risk antipsychotics + additional risk factors 3: Commence metformin with any antipsychotic if >3% increase in body weight in 1st year
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Aoife Carolan
Aoife Carolan@carolanaoife·
Weight gain is one of the most common and distressing side-effects of antipsychotic medicines. But, co-commencement of metformin with can reduce the extent of weight gain by 4.03kg (95% CI -5.78kg to -2.28kg) compared to controls
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Aoife Carolan
Aoife Carolan@carolanaoife·
This is the first published guideline for metformin for the prevention of weight gain. We used AGREE II & GRADE methods. International experts in endocrinology, metabolic psychiatry, pharmacy, general practice and patient & public partners came together to agree recommendations.
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Aoife Carolan
Aoife Carolan@carolanaoife·
Take a screenshot 📸 to save the algorithm to your phone now
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POPSUK
POPSUK@POPSUKORG·
@SarahJPharm @Davidiris1 Presented or written, that would be great. I’m feeling a bit ignorant for not being aware before.
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Sarah Jones
Sarah Jones@SarahJPharm·
@Davidiris1 makes a v. powerful point about how disempowered he felt as a parent in the mental health system, (even with his privileges as a white, articulate, healthcare professional who was used to being listened to). A feeling that's never left him. We must do better #CMHP24
The Mental Elf@Mental_Elf

@CarolineMHPharm Welcome to the #CMHP24 Memorial Lecture, given this year by Dr David Shiers Carer and Retired GP @Davidiris1 “Your Job is to Become an Expert in Her Medicines. A Conversation with a Carer.” @CMHPCommunity

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