Congratulations Dr. Alexandra Miller for defending her thesis today on iron and oxidative stress in M. Smegmatis 🦠!!
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Ehrt & Schnappinger Labs
115 posts
Ehrt & Schnappinger Labs
@EhrtSchnapLab
Ehrt and Schnappinger Lab (Weill Cornell Medicine). Tuberculosis Research. Account run by graduate students, because the concept of free time scares us.
New York, NY Beigetreten Mart 2019
97 Folgt553 Follower
Ehrt & Schnappinger Labs retweetet
Repurpose T cell self-reactivity for #cancer #immunosurveillance . Check out our new study @Nature by brilliant @CancerResearch fellows Chun Chou and @XianZhang2016 with help from @chirag_msk @JoshSmithMDPhD and other @MSKCancerCenter colleagues. rdcu.be/cLLaG
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Thank you to all authors, @Robert_S_Jansen @AlexandreGouzy @0098Wang @vdartois1 @rheelab @saehrt and others who are not on twitter.
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We found that inactivation of CinA increased efficacy of Isoniazid during treatment of chronically infected mice as well as enhanced in vivo killing of M.tb by a combination of Pretomanid, Bedaquiline and linezolid that is used to treat drug-resistant tuberculosis patients. 4/4
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Excited to share the latest work from our lab and @KajKreutzfeldt. This was a great collaborative effort seeking to elucidate how M. tuberculosis gene cinA mediates tolerance to multiple clinically relevant drugs. (1/4)
nature.com/articles/s4146…
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Ehrt & Schnappinger Labs retweetet
We are pleased to share Rhee Lab Website:
Credits: @SakilaNazia @sonivijay07
rheelab.weill.cornell.edu
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Ehrt & Schnappinger Labs retweetet
Congratulations to IMP student Chantal Harris who has just defended her PhD thesis "Metabolic Regulation of Sexual Differentiation in Human Malaria Parasites"!!!
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Ehrt & Schnappinger Labs retweetet
@MerWright13 @EhrtSchnapLab Recruitment today and @HarmanjitBansal gave an awesome RIP talk!! So fun to meet the recruits 😊
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It’s not always all or nothing. Barbara Bosch and Michael DeJesus explain how quantifying target vulnerability helps prioritize TB targets for drug discovery. @CellCellPress @RockLabTB @EhrtSchnapLab @RockefellerUniv #JRNLclub jrnlclub.org/research-films…
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"Did we just give Mycobacterium tuberculosis a metabolic disease?"
Really cool story #BehindThePaper by @tiagobeites @saehrt @EhrtSchnapLab @WeillCornell
"The characterization of the membrane oxidoreductase EtfD started as a "my gene" kind of story..."
go.nature.com/3o8FWOp
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Ehrt & Schnappinger Labs retweetet
Our latest paper “Multiple acyl-CoA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection” @EhrtSchnapLab, @WeillCornell was chosen as an Editor's Highlight @NatureComms. Really grateful for the recognition. nature.com/collections/je…
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Having trouble falling asleep wondering if it's possible to starve M. tuberculosis to death? Me neither. But if you find the topic interesting check out our last paper. Also, I've shared a more personal account of the story in the Nature Communities blog. go.nature.com/3kDgApJ
Ehrt & Schnappinger Labs@EhrtSchnapLab
@tiagobeites et al from the lab found that in Mtb, the lack of etfD results in a block in β-oxidation at the step catalyzed by acyl-CoA dehydrogenases rendering the mutant unable to grow on fatty acids and making the long chain fatty acids bactericidal. nature.com/articles/s4146…
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@tiagobeites et al from the lab found that in Mtb, the lack of etfD results in a block in β-oxidation at the step catalyzed by acyl-CoA dehydrogenases rendering the mutant unable to grow on fatty acids and making the long chain fatty acids bactericidal.
nature.com/articles/s4146…
Manhattan, NY 🇺🇸 English
Ehrt & Schnappinger Labs retweetet
Dear Twitter algorithm I’m looking for faculty positions, please send me more opening announcements and less top5 goals of champions league 97/98. I know it’s partly my fault, but I’m trying to do better. Also remember my kindness when AI decides to take over. Best wishes.
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Welcome @WCM_IMP to Twitterverse!
Immunology & Microbial Pathogenesis (IMP) Program@WCM_IMP
The IMP Program is on Twitter!! Follow us for all news concerning our graduate students, postdocs, and faculty in the Immunology and Microbial Pathogenesis (IMP) Program. @WeillCornell @sloan_kettering @HSpecialSurgery gradschool.weill.cornell.edu/programs/immun…
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Ehrt & Schnappinger Labs retweetet
Multiform antimicrobial resistance from a metabolic mutation advances.sciencemag.org/content/7/35/e…
Beautiful paper by @JVaubourgeix @shiruixia et al.!
👏👏👏
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Eloquent case for lab meetings' benefit.
Kay M Tye PhD@kaymtye
Lab Meetings are Sacred to me Evidence: I have never missed a single lab meeting in ~10 years, at least 300 lab meetings. Philosophy: This is where we honor our team members with our shared attention and thoughtful engagement, and they honor us with their preparation. 1/n
Manhattan, NY 🇺🇸 English
We thank the editor, Lalita Ramakrishnan, University of Cambridge (@RamakrishnanLab)
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We hope that our growth model using an acidic and lipid-rich medium will help studying Mtb in conditions closer to those it faces in vivo. Further work from this project is ongoing so watch this space in the coming year!
Manhattan, NY 🇺🇸 English
@AlexandreGouzy and @healycl in collaboration with @KBiocrates from the Rhee Lab shed light on how acidic stress imposed by the host affects M. tuberculosis central carbon metabolism. Short summary thread: pnas.org/content/118/32…
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