Lenz_Group

ATP-Triggered Fe(CN)2CO Synthon Transfer from the Maturase HypCD to the Active Site of Apo-[NiFe]-Hydrogenase | Journal of the American Chemical Society @TUBerlin #ATP #Maturase #HypCD #ApoNiFeHydrogenase pubs.acs.org/doi/10.1021/ja…

doi.org/10.1021/jacs.4…. Happy to share that our work on [NiFe]-hydrogenase maturation is finally out in @J_A_C_S. Work carried out by @Anna_kkw (@lenz_group) featuring @UniSysCat members @frieli_deluxe @ChristianLimb19 @RappsilberLab @adambelsom @AndreaMroginski and @DesyP01 1/3

Diese Forschenden arbeiten an Enzymen, die für die #Energiewende interessant sind: den Hydrogenasen. Hydro-was? 😜 Lest das Interview und holt euch Antworten: berlin-university-alliance.de/wissenslabor/s… #Energie #Chemie @BerlinUAlliance

Diese Woche im Fokus des OFFENEN WISSENSLABORS! Lest rein, wenn euch interessiert, wie Enzyme es schaffen, super #nachhaltig Wasserstoff zu produzieren. #Energie #Katalyse

Die #Energiewende herbeiführen müssen letztlich wir Menschen, alle zusammen in Zusammenarbeit. Die Forschung von #UniSysCat an Enzymen kann aber neue Möglichkeiten eröffnen: wir lernen von den natürlichen Katalysatoren wie sie effizient und ressourcenschonend #Energie umwandeln.

A Strep-Tag Imprinted Polymer Platform for Heterogenous Bio(electro)catalysis (Ingo Zebger and co-workers) @TUBerlin @UniSysCat @armel_waffo @Giorgio_Caserta @frieli_deluxe @jdragelj @Lenz_Group. #OpenAccess onlinelibrary.wiley.com/doi/10.1002/an…

We had a fantastic JBIC session @eurobic17, great science and a diverse line-up of speakers. Thanks to all speakers and the audience! @Springer_Chem #EuroBIC17

Our preprint is out! We provide the most comprehensive characterization of the hydrogenase maturase complex HypCD. Using transfer assays, Alphafold predictions, cross linking MS (and more) we show how the Fe(CN)2CO fragment is safely transferred to the apo hydrogenase using ATP!

Work brought to an end by @Anna_kkw in collaboration with many @UniSysCat groups. @Lenz_Group @ChristianLimb19 @DesyP01 @TUB_Chem @frieli_deluxe @AndreaMroginski

NEW in @ChemicalScience 🌟 Stepwise conversion of the Cys6[4Fe–3S] to a Cys4[4Fe–4S] cluster and its impact on the oxygen tolerance of [NiFe]-hydrogenase by Ingo Zebger, Oliver Lenz, Patrick Scheerer et al. 🔗 doi.org/10.1039/D3SC03… @Lenz_Group @frieli_deluxe @ArmstrongOxford

In our new joint article doi.org/10.1039/D3SC03… in @ChemicalScience, we have modified and analyzed the unique [4Fe-3S] cluster of a true O2-tolerant [NiFe]-hydrogenase, revealing a refined picture of O2-tolerant H2/H+ cycling. @Lenz_Group, @frieli_deluxe, @ArmstrongOxford

Research Highlight: A team of #UniSysCat researchers deciphers how a hydrogenase can make itself more tolerant against oxygen - a step that is important in developing #hydrogen #energy strategies & for regenerating nucleotide cofactors. #catalysis @J_A_C_S unisyscat.de/news-events/ne…

nature.com/articles/s4158… I´m glad it is finally out our work on the assembly of the [NiFe]-hydrogenase active site.@Lenz_Group @frieli_deluxe @ZwennH @CeeVeeEss1 @ChristianLimb19 @TUBerlin @UniSysCat @HumboldtUni @desy @spring8pr @mpicec_press @nchembio #hydrogen #energy

From our collection celebrating 10 years of ChemComm Emerging Investigators: 'A hydrogen-driven biocatalytic approach to recycling synthetic analogues of NAD(P)H' 🔓 by @vincentgroupox, @Caroline_E_Paul and first author Holly Reeve. rsc.li/3QnQlkb

Reversible Glutamate Coordination to High-Valent Nickel Protects the Active Site of a [NiFe] Hydrogenase from Oxygen @FU_Berlin @UniSysCat @Lenz_Group @TUBerlin #Glutamate #Nickel #Hydrogenase #Oxygen pubs.acs.org/doi/10.1021/ja…

Lenz, Zebger, and Horch investigate O2-inhibited states of the unique [NiFe]-hydrogenase HtSH (doi.org/10.1126/scienc… @ScienceMagazine), find the nickel ion switching between Ni(III) and, wait for it, Ni(IV) 🤩 Cool spectroscopy, out now with @J_A_C_S doi.org/10.1021/jacs.2…

Great collaborative project from @Lenz_Group @frieli_deluxe involving @UniSysCat members as well as national and international collaborators @CeeVeeEss1

We dissected the assembly mechanism of the NiFe(CN)2(CO) active site and isolated previously uncharacterized intermediates of the hydrogenase catalytic subunit.

Active site assembly of [NiFe]-hydrogenase scrutinized on the basis of purified maturation intermediates | ChemRxiv doi.org/10.26434/chemr…

3rd article of the #hydrogenase Research Topic @FrontMicrobiol has been released: doi.org/10.3389/fmicb.… Nice work on heterologous H2ase production in E. coli by Neubauer group @TUBerlin @Lenz_Group @GiorgioCaserta8 @UniSysCat Still accepting articles! frontiersin.org/research-topic…