Miguel Sousa Uva

@STS_CTsurgery @MMarinCuartas Congrats Mateo

In this article, Dr. @MMarinCuartas, of Leipzig Heart Center in Germany, explores how TAVI has changed the landscape of care for patients with severe aortic stenosis and why age alone shouldn't drive clinical decision-making. Read more: ow.ly/TvkG50Wu0vJ #CTsurgery

@MMarinCuartas @AATSHQ Hi Mateocongratulations👍👏can you share your research Thanks Happy New Year

🔔 Honored to present at #MitralConclave2025 by @AATSHQ our intestinal preconditioning protocol in tricuspid valve surgery at Leipzig Heart Center. Vasoplegia reduced to 0%, with lower mortality & shorter ICU/hospital stay. Accepted in Annals of Thoracic Surgery – Short Reports.

European defence governance and financing cepr.org/voxeu/columns/… # via @cepr_org Russian aggression, shifting US commitments, global competition over trade, technology, critical minerals, talent, intellectual property create a narrow window Urgency cannot be over started

🎙️ A Cut Above podcast — The new episode is live now! Recorded live at the EACTS Annual Meeting, this special episode delves into the theme “Nightmares in CABG.” Join hosts @FaisalBakaeen, Thomas Gudbjartsson and @Migas2001 for an open and practical discussion on the challenges of coronary surgery. From fragile conduits and calcified aortas to dissected mammary arteries and “full metal jacket” targets, the panel shares their approaches to complex scenarios, offering valuable insights on preparation, technique and team communication. The conversation highlights patient assessment, intraoperative decision-making and the humility required to learn from complications. It closes with reflections on mentorship, transparency and the power of honest debriefing in shaping safer surgical practice. 🎥 Watch the full episode here: vimeo.com/1128789914?sha… 🎧 Listen to the podcast here: eacts.org/publications/a…

PARTNER 3 at 7 years can be read both ways like a glass half empty or half full However as @kaulcsmv and @drjohnm pointed out HR less appropriate due to non proportionality OR upper bound for death is almost 2x greater for TAVR and seems important in low risk patients

I wouldn’t say 37% higher risk of stroke or death is an even match. At least from the patients perspective.

I believe the key issue is this "vital sweep" mentioned in the paper — a term I had never encountered before. Interestingly, the curves you refer to are in the supplementary materials and correspond to the non-sweep analysis. Those in the main paper are less separated and refer to the sweep analysis, in which they retrieved vital status for a substantial number of patients, apparently mostly surgical ones. Of course, if the idea was to let readers choose which set of curves they prefer, it doesn’t seem like a particularly sound approach. In any case, collecting follow-up data beyond five years clearly remains a major challenge.

@DFCapodanno I believe the key issue is the violation of non proportional hazard. When OR is calculated (as occurs when this happens) TAVR has higher risk of stroke or death. This extremely dangerous considering the velocity with which cardiological societies are pushing TAVR to younger pts.

IMPORTANT Hazard ratio for higher death in TAVR arm may be less appropriate due to non-proportional results in years 1-7. As Sanjay writes, the odds ratio of death or disabling stroke at 7 years is 1.37 and upper bound is nearly 2x worse for TAVR. Seems important in low-risk pts

@JiaJennyLiu @curijoey Thanks to you Faisal and Tomás We learn till we die and our mission is to transmit Knowledge 👍

Totally agree @curijoey - taking a post-#ESMO25 recovery pause in your beautiful home country 🇮🇹 🍷🫒⛪️ at the moment… before return to #drugdevelopment rat race! 🇦🇺

@drjohnm We all know Valve replacement either SAVR or TAVR have >0 hospital risk and just replaces one disease by another plus the risk of endocarditis or pace maker

I agree w Dr Dayan. Normally, I downgrade COI as an argument, but in this case the availability of TAVI is surely a tailwind behind lowering the threshold of aortic valve intervention. Thus COI is important. But also, the evidentiary basis is weak. I will write more on this.

@VictorDayan1 Fully agree

It is really sad how this type of editorials devoid of any substantial arguments with historically re-known authors aim at influencing and put pressure on guide modification

Just read this viewpoint from re-known authors regarding asymptomatic aortic stenosis. As expected I disagree 200% and feel the ground is being pushed for an unfortunate guideline modification. My reasons….(1/x) jamanetwork.com/journals/jamac…

@APIC_pt Muitos parabéns Obrigado pelos milhares de vidas salvas

🔔 Este ano assinala-se o 25.º aniversário da Via Verde Coronária (VVC), uma iniciativa que transformou o panorama das emergências cardíacas em Portugal. Para assinalar este quarto de século de existência, a Associação Portuguesa de Intervenção Cardiovascular (APIC) lançou a revista comemorativa "𝟐𝟓 𝗮𝗻𝗼𝘀 𝗱𝗲 𝗩𝗶𝗮 𝗩𝗲𝗿𝗱𝗲 𝗖𝗼𝗿𝗼𝗻á𝗿𝗶𝗮 𝗲𝗺 𝗣𝗼𝗿𝘁𝘂𝗴𝗮𝗹 - 𝗘𝘃𝗼𝗹𝘂çã𝗼, 𝗜𝗺𝗽𝗮𝗰𝘁𝗼𝘀 𝗲 𝗗𝗲𝘀𝗮𝗳𝗶𝗼𝘀 𝗙𝘂𝘁𝘂𝗿𝗼𝘀", na qual são partilhadas várias perspetivas sobre a evolução da VVC, os impactos na saúde cardiovascular dos portugueses e os desafios que se colocam no futuro. A APIC agradece a todos os que contribuíram de alguma forma para a realização deste documento. Que esta data seja uma inspiração para continuarmos a salvar vidas, juntos! ❤️ 👉 Leia a revista aqui: online.pubhtml5.com/vqxre/hjtt/

@AATSHQ @UVA_TCV_Surgery @hunter_mehaffey @robertbhawkins @EvanRotarMD @nickteman Not surprising results for me

New research article from Seminars in Thoracic and Cardiovascular Surgery: #OR Versus #ICU Extubation Within 6 Hours After On-Pump #Cardiac Surgery: Early Results and Hospital Costs. Read now: doi.org/10.1053/j.semt…

@VictorDayan1 Nice picture 👍

Preparing my talk for Guayaquil…the achilles heel of ALL TAVI vs SAVR trials is this👇…

Concerns were raised with the 5 year data of PARTNER 3 regarding mortality (higher with TAVR). The 6 year data posted at the @US_FDA show that curves continue to diverge…..

@georgetolisjr The same with us

Open AVR is nationally becoming an operation of the sick and elderly and TAVI an operation of the young and healthy. Makes no sense whatsoever. We are so fortunate at BWH not to follow that trend because of the quality of our clinical and structural cardiologists.

@VictorDayan1 Congratulations Ruí

Great friend, great mentor and councilor. Hope and wish for the best.