#PHMFellowJC

736 posts

#PHMFellowJC

@PHMFellowJC

Official Twitter account and moderator for #PHMFellowJC. Now hosting with @PedsICU_JC. Journal clubs will run throughout the course of the day!

Beigetreten Eylül 2018

6 Folgt272 Follower

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#PHMFellowJC@PHMFellowJC·19 Mar

We can’t wait for our #EBM chat w/ @MedStudentChat on Thurs, 3/19, at 9 pm EST. Here are our updated objectives, tips to participate in #PHMFellowJC & a link to a fun article on a RCT looking at the association b/w eating ice cream quickly and headache! ncbi.nlm.nih.gov/pmc/articles/P…

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Sonya Tang Girdwood 鄧智佳, MD, PhD@STangGirdwood·20 Mar

#PHMFellowJC #MedStudentChat #MedStudentTwitter T7: D) @DrJenChen4kids already talked about generalizability. Middle schoolers do not represent whole population No blinding: not sure how you would have done that for this study That said, amazing thiswas done by an 8th grader!!

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Sonya Tang Girdwood 鄧智佳, MD, PhD@STangGirdwood·20 Mar

#PHMFellowJC #MedStudentChat #MedStudentTwitter T7: C) For NNH, it’s the number of people who need to be exposed for there to be a person to have the negative outcome, who would not have had the outcome if not exposed. Related term: number needed to treat

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Sonya Tang Girdwood 鄧智佳, MD, PhD@STangGirdwood·20 Mar

#PHMFellowJC #MedStudentChat #MedStudentTwitter T7: B) For RR, if I have a patient who was exposed to something (eg eating 🍨 quickly), it is the increased (or decreased) chance of having an outcome (headache) compared to the unexposed person (eating ice cream slowly)

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Sonya Tang Girdwood 鄧智佳, MD, PhD@STangGirdwood·20 Mar

#PHMFellowJC #MedStudentChat #MedStudentTwitter T7: A) continued: The other way people look at p < 0.05 is that there’s a less than 5% chance we mistakenly rejected the null hypothesis. The null hypothesis usually says no difference

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Sonya Tang Girdwood 鄧智佳, MD, PhD@STangGirdwood·20 Mar

#PHMFellowJC #MedStudentChat #MedStudentTwitter T7: A)p<0.05 is threshold researchers have agreed upon for statistical significance. It means there’s less than 5% chance that the differences aren’t true (Type I error). But statist. significant doesn’t mean clinical significant

#PHMFellowJC@PHMFellowJC

Last set of questions! Y'all are doing awesome! T7: EBM, Math, Limitations a) What does p<0.05 mean? b) What does relative risk mean clinically? c) What does Number Needed to Harm mean clinically? d) Limitations of the study? Use #PHMFellowJC & #MedStudentChat & T7

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Sonya Tang Girdwood 鄧智佳, MD, PhD@STangGirdwood·20 Mar

Not only does this article have great teaching points but is short and fun to read, the first author was in 8th grade when she wrote it! And she still claims to love ice cream! mayakaczorowski.com #PHMFellowJC #MedStudentChat

#PHMFellowJC@PHMFellowJC

Whew! We made it! We hope you learned something and had fun during our chat! We covered a lot so go back and search #PHMFellowJC and #MedStudentChat at your own pace to review the material. We will post a moment and transcript when we can. DM @PHMFellowJC w/ ?s! Thanks all!

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#PHMFellowJC@PHMFellowJC·20 Mar

@archbabu @DrJenChen4kids @STangGirdwood @maha_kaissi @AudreyUongMD @jmomdphd @kedkyler @herchd Thanks for joining us at #PHMFellowJC and #MedStudentChat!

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#PHMFellowJC@PHMFellowJC·20 Mar

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#PHMFellowJC@PHMFellowJC·20 Mar

#PHMFellowJC #MedStudentChat

AudreyUongMD@AudreyUongMD

@archbabu @jmomdphd @PHMFellowJC @MontefiorePeds I sometimes use the BU website (bu.edu/otlt/mph-modul…)<-explaining Mann Whitney. Sometimes it’s a bit technical, but the intro stuff is helpful.

QHT

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Dr. Jennifer Chen, MD FAAP 林明堯@DrJenChen4kids·20 Mar

#PHMfellowJC #MedstudentChat T6 a) Helps show the two groups are similar prior to intervention (mostly were, so probably valid) b) ⬆️ headache in rapid eating group

#PHMFellowJC@PHMFellowJC

On to the results! T6: a) Why do studies report baseline characteristics? Based on table, would you consider the results valid? b) What were the results of the primary outcome? c) What is intention-to-treat? Did it matter here? Use #PHMFellowJC and #MedStudentChat & T6

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#PHMFellowJC@PHMFellowJC·20 Mar

@maha_kaissi Thanks for joining us! See you next time Maha!

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#PHMFellowJC@PHMFellowJC·20 Mar

Anyone want to take a stab at answering these questions? You don't even need to read the article to answer 7a-c! #PHMFellowJC #MedStudentChat

#PHMFellowJC@PHMFellowJC

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Kate Kyler, MD@kedkyler·20 Mar

For example, if a kid in the slow ice cream group had wolfed their ice cream down (It me 🙋🏻‍♀️), they would still be analyzed as part of the group they were assigned to. #rulebreaker #PHMFellowJC #MedStudentChat

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Kate Kyler, MD@kedkyler·20 Mar

@PHMFellowJC If they’d analyzed per protocol, only those participants who followed the 🍦 eating rules could be included in the final analysis, decreasing the sample size and introducing bias. Here’s an article about why ITT is important! #PHMFellowJC #MedStudentChat ncbi.nlm.nih.gov/pmc/articles/P…

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Dr. Jennifer Chen, MD FAAP 林明堯@DrJenChen4kids·20 Mar

@PHMFellowJC #PHMFellowJC #MedStudentChat Generalizability is the idea of whether the research is applicable (or not) to your own patient/population, eg a study on asthma in ex-preemies (who likely have other issues such as CLD) might not be helpful for treating normal full-term kids w asthma

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Kate Kyler, MD@kedkyler·20 Mar

@PHMFellowJC They generally look similar, except for gender. Somehow, the slow eating group ended up w more girls. So that might make you question the results; what if girls are less likely to have headaches in general? Or less likely to complain? 🤪 #jk #PHMFellowJC #MedStudentChat

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#PHMFellowJC@PHMFellowJC·20 Mar

Great way of explaining it, @maha_kaissi: Concealment: Blinding the randomization process so you the system can't be played Blinding: Blinding the participants and researchers from knowing who got the intervention. #PHMFellowJC #MedStudentChat

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John@jmomdphd·20 Mar

Agree! “Table 1” is often overlooked during critical appraisal of a manuscript! #PHMFellowJC

Kate Kyler, MD@kedkyler

T6a: baseline characteristics are important in every study, to compare differences between cohorts, and to give an idea of how the study population compares to the general population (or whatever population is most applicable to you). #PHMFellowJC #MedStudentChat

Florida, USA 🇺🇸 English

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Dr. Jennifer Chen, MD FAAP 林明堯@DrJenChen4kids·20 Mar

#PHMfellowJC #MedStudentChat T6c: ITT means students kept in orig group even if they didn’t follow directions eg someone in fast-eating group ate slowly instead. Not sure how much it mattered in this study but here’s a quick ref of pros/cons for RCTs litfl.com/intention-to-t…

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#PHMFellowJC@PHMFellowJC·20 Mar

@DrJenChen4kids Ooh, we're touching upon generalizability. Tell us more about that topic! #PHMFellowJC #MedStudentChat

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Dr. Jennifer Chen, MD FAAP 林明堯@DrJenChen4kids·20 Mar

@PHMFellowJC #PHMFellowJC #MedStudentChat I’d say take your time so you feel satisfied and don’t got back for more ice cream, but that’s another discussion altogether. Also, this study was only in middle school kids so may not apply as well to adults 😜

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#PHMFellowJC@PHMFellowJC·20 Mar

So does that mean we should take our time enjoying our ice cream so we don't get headaches? #PHMFellowJC #MedStudentChat

Dr. Jennifer Chen, MD FAAP 林明堯@DrJenChen4kids

#PHMfellowJC #MedstudentChat T6 a) Helps show the two groups are similar prior to intervention (mostly were, so probably valid) b) ⬆️ headache in rapid eating group

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@DrJenChen4kids @STangGirdwood @AudreyUongMD @jmomdphd @kedkyler @herchd @elonmusk @BarackObama