Rheumatology International

🎉 Congratulations to the Rheumatology International editorial team! 🏅 Recognised by Springer Nature for editorial excellence, based on outstanding author feedback. Your passion and commitment shape the future of rheumatology publishing. link.springer.com/journal/296/up…

🧩Understanding “Psout” — when #PsA meets #gout 👉doi.org/10.1007/s00296… ✅Shared pathophysiology: uric acid–driven inflammation via IL-23/IL-17 axis ✅“Psout” = more peripheral, destructive, and treatment-resistant phenotype ✅Early recognition essential

🦋#Lupus arthritis-ultrasound insights doi.org/10.1007/s00296… 📊In a large #SLE cohort: 🤲Wrists & 🦵knees = most commonly inflamed joints+often cluster together 🔬Low-grade synovitis frequent - highlighting the value of US to detect subclinical inflammation beyond clinical exam

On #WorldArthritisDay, Rheumatology International reaffirms its mission to connect global research and clinical excellence. We publish high-quality evidence that advances understanding and improves patient care. 🔗 Read the latest evidence: link.springer.com/journal/296

🧩 #ASIAsyndrome — rare but increasingly seen after #implants or #fillers. Think ASIA when unexplained autoimmune symptoms follow adjuvant exposure. Ultrasound can aid diagnosis!! 👉rdcu.be/eKvGU

Inflammatory arthritis affects work In POLNOR-Rheuma cohort (n=1,060),patients with RA,PsA,axSpA had similar work impairment (25-28%) but RA/PsA showed greater limitations ✅High disease activity=worse productivity ✅Annual indirect costs €1.21 billion rdcu.be/eJ5Gi

Depicting gouty arthritis at the Royal Court of Spain: the case of Pablo de Valladolid (1587–1648), the jester of King Philip IV 👉rdcu.be/eJ5BA

🧬 Patients with Sjögren’s disease have a >15× higher risk of lymphoma vs the general population. 🔹 Cryoglobulinemia = strongest predictor 🔹 >50% of deaths in SjD+lymphoma due to the malignancy Large Spanish prospective cohort study 👉rdcu.be/eJ5kJ

End-stage kidney disease in #lupus — new insights from doi.org/10.1007/s00296… Among 2837 SLE patients, 7.4%➡️ESKD ⚠️Higher risk in men (HR 3.37) and Māori/Pacific (HR≈4.6). 💔Māori patients had poorer survival (HR 2.17). Action needed to ⬇️disparities & improve outcomes

Early vs.delayed #lupusNephritis by @KaWegiel68670 et al. doi.org/10.1007/s00296… Delayed-onset LN-сlose monitoring is key: ➡️more severe disease ➡️higher prevalence of anti-dsDNA,anti-Sm,anti-Ro, anti-RNP ➡️greater need for intensive immunosuppression ➡️class IV most common

🌿#Lifestyle matters in #lupus! A systematic review of 102 studies by @IoannisParodis et al. doi.org/10.1007/s00296… 💪Exercise⬇️fatigue & boosts mood 🧠Psychological support improves anxiety & quality of life 🥗Mediterranean & low-fat diets⬇️CV risk ☀️UV protection is essential

Tongue necrosis=Think GCA! 👉rdcu.be/eGdD9 ✅Rare (2–4%) but can be first sign of #GCA (in ~33% cases) ✅50 y/o + lingual ischemia?🔎Rule out GCA ✅High risk of vision loss & tissue damage if missed ✅Tx: GC, add TCZ if relapse/refractory

🆕by @RheumKrakow 👉doi.org/10.1007/s00296… 🔹In #SLE VCAM-1 levels↑vs controls ➡️but no difference between active & inactive disease 📌Still, VCAM-1 correlated with disease activity 🔹PECAM-1 & ICAM-1→limited diagnostic utility 📈though PECAM-1 linked with disease duration

🧬 VEXAS syndrome: a challenging autoinflammatory disorder caused by somatic UBA1 mutations – Multisystem inflammation – Cytopenias – Steroid-sparing response to IL-1 & IL-6 inhibitors 🧪Early genetic testing is key 🧠Curative option: HSCT(limited by age) rdcu.be/eEEsI

How do rheumatologists screen for #RA-#ILD? A national survey shows wide variation ✅Chest CT (77.6%), X-ray (72.9%), PFTs (65.4%) 📌Many screen only if symptoms present 📉 Limited DLCO access & MDT support in some settings➡️ Standardized approaches needed rdcu.be/eEEiG

🤖Can #ChatGPT help diagnose rheumatic diseases? ✅ChatGPT-4 listed correct diagnosis among top 3 in 60% of cases vs. 55% for rheumatologists ✅For confirmed IRD cases, it reached 86% accuracy in top 3 (vs. 74%) 🔍AI may assist in early detection & triage doi.org/10.1007/s00296…

This new review by Dr. Kamil Koszela et al. highlights the role of spinal #mesotherapy in chronic back pain syndrome: 📚 800+ patients across 9 studies ✅ Effective to reduce pain, restore mobility & enhance quality of life ❌ No serious adverse events 👉doi.org/10.1007/s00296…

🧪 New study: Uric acid & inflammation in older adults 📈 Untreated hyperuricemia = ↑ IL-6 & IL-1β 📉 Proper treatment = ↓ IL-1β 💡 Uric acid control may help modulate inflammation 🧬 More research needed — but clinical impact is clear! doi.org/10.1007/s00296…

🔥Highly cited in Rheumatology International! How well does #AI advise patients on 💊methotrexate? This study compares ChatGPT, BARD & Bing. 📊 GPT-4: 100% accurate and complete ⚠️ BARD & Bing: errors and hallucinations 📖 Read the full text: rdcu.be/eycUU

Rheumatoid #RA hand massage therapy to mitigate #sarcopenia and improve patients’ quality of life: a hypothesis by @BurhanFatihKoy1 et al. 👉rdcu.be/ex2VF

#5 Systematic review of associations between concomitant rheumatoid arthritis and peripheral arterial disease, health-related quality of life and functional capacity 👉doi.org/10.1007/s00296…

#4 Role of glucosamine in the treatment for osteoarthritis 👉rdcu.be/ex2QN

📊 Top 5 most discussed articles from Rheumatology International in the past 12 months — according to @Altmetric! Explore what sparked the most attention across the rheumatology community. 🧵Thread below ⬇️