Scofield Laboratory

Having an awesome ISBRA meeting here in Melbourne. We had a really fun panel on neuronal and glial consequences of drug use. Many thanks to @ISBRAComm and @RobynBrownLab. Fantastic talks from @KateReissner, Xavier Maddern, and @morganjameslab,

Application to present at the Second Italian Glia Network Symposium is closing next week. Apply your abstract by Oct 10!!! Do not miss the opportunity to discuss your research in a young and informal community !!! italianglianetwork.com/event-details/…

In the latest issue! A postnatal molecular switch drives activity-dependent maturation of parvalbumin interneurons dlvr.it/TNS6vq

Online now: Dysfunction of cortical GABAergic projection neurons as a major hallmark in a model of neuropsychiatric syndrome dlvr.it/TNGVLl

Awesome analyes led by Hayley Thorpe (from @JKhokharLab) on how to optimize social media initiatives in @npp_journal!

Review: A neural manifold view of the brain nature.com/articles/s4159…

Excited to share our development of a novel model of TMD pain lead by @daspainbrain with @andpru! Developing a model of temporomandibular disorder in the common marmoset using nerve growth factor biorxiv.org/content/10.110…

Really interesting papers, confirming and extending what many believed true for a while. The last 20 years gave us the illusion of super hyper specialization of brain regions thanks to opto/chemogenetics. Turns out we were just under a lamppost. We're in a "neo-Lashley" era. Brain functions are mostly spread out throughout the brain, not in one spot. If you’re not already looking elsewhere than under the lamppost, you should.

Psychedelics and Non-hallucinogenic Analogs Work Through the Same Receptor, Up to a Point ucdavis.edu/news/psychedel…

Happy to share my students’ study @CellReports Parvalbumin interneurons in the insular cortex control social familiarity and emotion recognition: Cell Reports cell.com/cell-reports/f…

"Dopamine was associated with reward learning or sensitivity (SMD, 0.26), and reward vigor (SMD, 0.32). By contrast, serotonin was associated with punishment learning or sensitivity (SMD), and aversive pavlovian processes (within-participant studies only; SMD, 0.36)."

And just like that #CannabinoidGRC2025 comes to an end! Big thank you to my co-chair @CeceHillard and all the attendees and speakers! Congrats to @mayoonthebrain and @ryanmcpickle on their selection as chairs for the 2029 meeting!

📣 NEW: Breakthrough discovery of a genetic link to pain co-led by NDCN's Prof David Bennett and Prof Simon Newstead @BiochemOxford The results of the research, published in @Nature, could lead to a promising new target for the treatment of #chronicpain.

📈 New data from NIH-supported Monitoring the Future study at @UMich shows increases in nicotine pouch, cannabis, vaping, & psychedelic use among adults. Monitoring these trends is vital to set smart public health priorities. 🔗Read more: news.umich.edu/nicotine-pouch…

Astrocytes in the medial entorhinal cortex are required for spatial exploration dlvr.it/TMcnDk

Online now: Microglia regulate neuronal activity via structural remodeling of astrocytes dlvr.it/TMZKf2

Join us this Thursday for the last #AstrocyteCafe session of this edition!!! Looking forward to hearing the talks by @Avishek92 , @Holt_LewisRhys and Kerstin Lenk!😍😎 Register for our free mailing list or email us to get the link ;)

🚨 First paper from the Bocchi lab out now in @NatureComms! We show that astrocytes in the cortex arise from not one, but two distinct progenitor lineages, each giving rise to specialized subtypes with distinct roles. Here the story📖 doi.org/10.1038/s41467… See 🧵below for more.

Machine Learning with PyTorch and Scikit-Learn Link - amzn.to/4onLYb0 #MachineLearning #ML #AI #SoftwareEngineering #DeepLearning #DataAnalytics #DataScience #PyTorch #Python #programming

Activity of CRF neurons in the BNST reduces anxiety-potentiated startle in female rats in an estrous phase-dependent manner biologicalpsychiatryjournal.com/article/S0006-…

Are you interested in #microglia, #astrocytes and #purinergic P2X7R? Have a look to our new review 🤗🥰 rdcu.be/exfKt @pizzolab22 @SpringerNature