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@aagha

Tweet about finance/investing, politics, tech, startups & science.

SF Bay Area, CA, USA Beigetreten Nisan 2008
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Marco Foster
Marco Foster@MarcoFoster_·
Tim Dillon on MAGA: “It’s the greatest con in history, truly. To run as America First and you’re gonna take care of America and then turn around and go all of these things daycare, Medicare, we have nothing to do with that, we’re fighting wars. It is the greatest scam in history”
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Tuki
Tuki@TukiFromKL·
🚨 do you understand what scientists just did to deafness.. researchers injected a modified harmless virus directly into the cochlea the spiral cavity in your inner ear.. carrying a working copy of a gene called OTOF.. the gene that transmits sound signals from your ear to your brain.. without it, your ear hears everything.. your brain receives nothing.. 10 completely deaf patients.. single injection.. within weeks all 10 could hear.. 10 out of 10.. here's what nobody wants to say.. cochlear implants cost between $30,000 and $100,000 per patient.. hearing aids sell for up to $7,000.. the global hearing industry is worth over $9 billion a year.. every year.. recurring.. because deafness has never been cured.. just managed.. one injection ends all of that.. and in 2018 goldman sachs analysts literally wrote this in a report about gene therapy.. "curing patients is not a sustainable business model" that's a goldman sachs equity research note.. sent to investors.. warning them that companies developing one-time cures were a risky bet because cured patients stop buying products.. the science to fix single broken genes has existed in research labs for years.. the same platform used here already cured a form of blindness in 2017.. cured spinal muscular atrophy in babies in 2019.. there are over 10,000 known single-gene disorders.. millions of people labelled "incurable".. the platform exists.. the proof is 10 out of 10.. the question was never whether they could fix it.. it's whether fixing it was good for business.
Polymarket@Polymarket

BREAKING: An experimental gene therapy ear injection has cured deafness for 10 out of 10 patients in clinical trial.

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Zabe
Zabe@aagha·
@Ric_RTP 100% this never happened
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Ricardo
Ricardo@Ric_RTP·
Sam Altman just admitted OpenAI deliberately keeps life-saving AI capabilities locked because they're too dangerous to release. A guy flew in from Australia to tell Altman how he used ChatGPT to design a custom mRNA vaccine for his dog's cancer. He had no medical background or research team. Did what would've taken an entire research institute with just ChatGPT. And the dog actually survived. Altman called it the coolest meeting he had all week. Then he admitted that OpenAI intentionally restricts how powerful their models can be in biology. Said more people could save lives if they "turned up the power." But they won't. Because that same power could let a terrorist group engineer a novel pandemic. So right now there is a version of ChatGPT that could potentially help cure diseases that OpenAI will not give you access to. Not because it doesn't work but because it works TOO well. And that tension defines everything about where AI is headed. Altman says within 2 years there will be more cognitive capacity inside data centers than inside every human brain on Earth combined. Automated AI researchers could compress 10 years of scientific progress into one year. Then 100 years into one year. A physicist using one of OpenAI's latest internal systems told Altman his mind was "completely blown" and that decades of theoretical physics breakthroughs are about to happen in the next couple of years. This is what nobody's paying attention to. Everyone's arguing about chatbots and which AI writes better emails. But the ACTUAL play is automated research that could reshape energy, medicine, and materials science faster than any institution can process. But Altman is also terrified of what happens when individuals get that much power. He says open source models will eventually be capable of designing pathogens. When that happens it won't matter what safety restrictions OpenAI puts on their products. The threat literally comes from everywhere. And here's the part that tells you everything about where his head is at: He won't let his own son use AI. The CEO of the most powerful AI company in history would rather be on the "late end of what's reasonable" when it comes to his kid using the technology HE built. He used to write his baby a letter every night about the decisions he was making at OpenAI. What went wrong. What he was worried about. What he decided and why. Said writing to your kid forces you to be the most honest version of yourself because you can't hide anything. His lawyers told him to stop. The man building the most powerful technology ever created was writing nightly confessions to his infant son about what he was doing. And the legal team said that's too DANGEROUS to continue. He also confirmed the first one-person billion-dollar company already exists. Built entirely by one founder using AI agents. No team. He promised not to share details until the founder announces it. And he killed Sora despite a billion-dollar Disney deal because "competing in short-form video would force OpenAI to optimize for addiction." The picture that emerges is a man who believes he's building something that could save or destroy civilization. And he's making trillion-dollar bets on the assumption he can thread that needle. - Locking up capabilities that could cure diseases because they could also engineer plagues - Deploying AI for the military while admitting he "miscalibrated" public trust - Raising a child he won't let touch the product he built That's not confidence. Sam Altman is negotiating with the future in real time and hoping he gets it right.
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Sar Haribhakti
Sar Haribhakti@sarthakgh·
Amazon now does 24-hour delivery for essentials to 1 in 5 households in rural and small town America It’s competing with Walmart which has a store within 10 miles for 90% Americans bloomberg.com/graphics/2026-…
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Roshan Rai
Roshan Rai@RoshanKrRaii·
This is the most EPIC thing you will ever read 🔥😂👏 US Journalist 🇺🇸: Professor Marandi , You are a US citizen born in Richmond, Virginia. You are eligible to be elected US President. Professor Marandi 🇮🇷 : I am not… Journalist : Why not? Professor Marandi : Because my name is not in the Epstein Files 😭😭
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The Hill & Valley Forum
The Hill & Valley Forum@HillValleyForum·
"Our head count in Manhattan when I got to JPMorgan was 35,000 and now is 26,000. Our head count in Texas started at 11,000, now it's 33,000. That's what happens." Jamie Dimon on why companies are leaving New York: "Highest individual taxes, highest estate taxes, highest corporate taxes, anti-business sentiment." "When I grew up as a kid in New York City, there were 120 of the Fortune 500 headquarters there. In the 1970s, 60 of the 120 left, including Exxon, GE, IBM, Union Carbide. They're all going to Texas." The Hill & Valley Forum 2026 @HillValleyForum @jpmorgan @ChairmanG
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Mark Slapinski
Mark Slapinski@mark_slapinski·
Pam Bondi sold her integrity and her soul for Trump. And he fired her anyway.
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StockMarket.News
StockMarket.News@_Investinq·
Someone placed an $800,000 bet that America is about to invade Iran on the ground. That same wallet correctly predicted the last three military strikes on Iran, every single time, hours before the bombs fell. This is not a coincidence and here is what is really going on. The US has been at war with Iran for over a month and American and Israeli forces struck Iranian nuclear sites in late February. But the uranium is still there and nearly 1,000 pounds of highly enriched uranium, enough to build multiple nuclear weapons is buried deep inside a mountain in Iran. Trump asked the Pentagon for a plan to go in and take it. There is reports that he wants to send soldiers into Iran, build a runway on Iranian soil, airlift in excavation equipment, and physically pull it out of the ground. The military briefed him on the operation and he has not said no. At the same time, the Atlantic reported that military planners have finalized two separate ground assault scenarios inside Iran, waiting only for Trump's green light. The Pentagon just sent 5,000 Marines trained for amphibious landings and 1,000 paratroopers to the Middle East. Now go back to that Polymarket wallet. It joined in January 2026 and it has made 57 predictions. It has an 83% overall win rate and a 93% win rate on bets over $10,000 concerning Iran specifically. It won $297,000 betting that the U.S. would strike Iran by February 28 and those bets were placed hours before the bombs dropped. Its newest bet is $800,000 on a US ground invasion of Iran. A finance professor and former CFTC advisory board member told CNN: "It certainly appears this individual either has extraordinary luck or was engaged in insider trading." Blockchain analysts say the pattern "strongly indicates insider activity." Someone with access to classified military decisions appears to be converting American war plans into personal profit and there is currently no law in the US that clearly makes this illegal, because Polymarket operates offshore.
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Brian Roemmele
Brian Roemmele@BrianRoemmele·
8 down…
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Republicans against Trump
Republicans against Trump@RpsAgainstTrump·
BREAKING: Trump’s former spiritual adviser, pastor Robert Preston Morris, has been released after serving just six months in jail for abusing a 12-year-old girl.
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محمدباقر قالیباف | MB Ghalibaf
Heads-up: Pre-market so-called “news” or “Truth” is often just a setup for profit-taking. Basically, it’s a reverse indicator. Do the opposite: If they pump it, short it. If they dump it, go long. See something tomorrow? You know the drill.
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Dmitrii
Dmitrii@dmitriid·
@SuperClawPaul @LoveAIcrew @trq212 @bcherny @lydiahallie You don't need to hire me to have common sense. But you *do* need common sense not to be an unpaid apologist for a $380-billion-dollar company. 2/2 tl;dr by someone else here: x.com/aagha/status/2…
Zabe@aagha

@trq212 @dmitriid @bcherny @lydiahallie This level of comms from a company so many people use us unacceptable. There's a clear way others have approached this: 1. Acknowledge a problem 2. State what it is 3. State how it happened 4. State how you'll fix it / make ammends 5. Apologize Right now, we barely have #1

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Tejash Mishra
Tejash Mishra@tejash_07·
Total 188 verbs Claude code uses Anthropic engineers must be contemplating today
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Zabe@aagha·
@trq212 @dmitriid @bcherny @lydiahallie This level of comms from a company so many people use us unacceptable. There's a clear way others have approached this: 1. Acknowledge a problem 2. State what it is 3. State how it happened 4. State how you'll fix it / make ammends 5. Apologize Right now, we barely have #1
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Dmitrii
Dmitrii@dmitriid·
How it started and how it's going over at "programmers will be obsolete yesterday" at the vibe coder camp. Yes, someone at reddit found (one) root cause faster than the combined might of "we only use claude" of @bcherny @trq212 @lydiahallie reddit.com/r/ClaudeAI/com…
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Fintwit Capital
Fintwit Capital@fan_fintwit·
Trump's Iran Downfall
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