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Ian Haydon
3.5K posts
Ian Haydon
@ichaydon
head of comms & AI policy @UWproteindesign 📝📸🎥 // @AAASMassMedia alum // used to study enzymes // he/him
Seattle, WA Beigetreten Haziran 2010
1.7K Folgt15.4K Follower
Was great to work on the #Alphafold3 announcement video, made with #b3d and #MolecularNodes #GeometryNodes
Isomorphic Labs@IsomorphicLabs
How could #AlphaFold 3 transform drug discovery? Most drugs are small molecules known as ligands that bind to proteins to change how they interact in human health and disease. AlphaFold 3 can predict these interactions to atomic accuracy.
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Ian Haydon retweetet
I'm excited to share that I'll be joining @MITBiology as an Asst Prof. in Jan 2024! Come join us! 🤓🧪🖥️🧬
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Ian Haydon retweetet
ICYMI: AI tools are designing entirely new proteins that could transform medicine nature.com/articles/d4158…
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Ian Haydon retweetet
Have you had a chance to use RFdiffusion?
We would love to hear about it! Please share your story here or send us an email: contact@ipd.uw.edu
bakerlab.org/2023/03/30/rf-…
Seattle, WA 🇺🇸 English
Ian Haydon retweetet
Generative AI for protein design is now one click away. We've launched a new platform that puts powerful tools behind a simple web interface, making #proteindesign accessible to everyone.
Full video ➡️ youtu.be/bS71K2U0amA
Try it here ➡️ huggingface.co/spaces/merle/P…
YouTube
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Ian Haydon retweetet
ARE YOU SICK OF AI?! BECAUSE WE DID IT AGAIN IN AN EVEN MORE OBSCURE SPACE THAN TEXT OR IMAGES. BUCKLE UP BECAUSE THIS WONT MAKE ANY SENSE UNLESS YOU LIKE PROTEINS 💃💃🧬🧵
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Ian Haydon retweetet
Generative AI for protein design is now one click away. We've launched a new platform that puts powerful tools behind a simple web interface, making #proteindesign accessible to anyone.
Try it here ➡️ huggingface.co/spaces/merle/P…
Learn more on YouTube ➡️ youtu.be/bS71K2U0amA
YouTube
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The most impactful use of generative AI may not be text, images, or video. My team @UWproteindesign is developing tools that literally generate new genes 🧬
We call this process protein design.
Here’s a beginner’s guide ⬇️
Institute for Protein Design@UWproteindesign
Ready to learn about protein design? Our beginner's guide breaks down this complex field into easy-to-understand concepts. Discover the potential of proteins to transform our world: ipd.uw.edu/2023/05/what-i…
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Ian Haydon retweetet
It's an incredible day for structure-based vaccine design, and I'm thrilled to see our prefusion RSV F antigen get approved as the first RSV vaccine. Still more work to do to reduce the RSV disease burden, but this will help! Congrats @BarneyGrahamMD! cnn.com/2023/05/03/hea…
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Ian Haydon retweetet
We are thrilled to share that Dr. Lynda Stuart has joined as our new Executive Director. With her extensive experience and dedication to healthcare as a human right, the future of protein design looks brighter than ever.
Learn more: ipd.uw.edu/2023/05/lynda-…
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Ian Haydon retweetet
Today we report the use of reinforcement learning, a strategy used to solve games like chess and Go, to a challenge in protein design. This milestone in using #AI for science may enable more effective cancer treatments & new biodegradable textiles.
science.org/doi/10.1126/sc…
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.@karaswisher: What's the greatest application of these new AI tools?
.@sama: They will greatly expand our scientific knowledge.
Kara: Isn't that already happening with folding proteins?
Sam: That's the one I am personally most excited about.
podcasts.apple.com/us/podcast/on-…
Seattle, WA 🇺🇸 English
Ian Haydon retweetet
It's not just #ChatGPT . There’s another facet of the #AI revolution, a marriage of deep learning and #biology , that’s at least as important, but far less widely understood @UWproteindesign @DeepMind @MetaAI wsj.com/articles/biolo…
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@notresz @DaveJuergens You're right — without guidance, denoising is mostly useless. That's why RFD is a guided diffusion model. It can be guided toward a defined topologies or symmetries, or it can be made to include specific protein features like binding or active sites.
biorxiv.org/content/10.110…
Seattle, WA 🇺🇸 English
@DaveJuergens I cant find what RFD does. All I've found so far just say that it is a denoiser and you feed it a random starting backbone. Wouldn't proteins "denoised" from random starting backbones most likely be useless, where is the "direction" in this process in the context of engineering?
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We’re very happy to announce that our RFdiffusion manuscript is now on bioRxiv! A lot can change in a week - we’ve now tested over a thousand designs and there’s so much exciting new data! 🧵
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I don’t really think of the beginning of the pandemic being particularly lonely, but then I look at the photos I took during that time and
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@soragnilab That is wild and scary!
It also made up that I have a family full of scientists. Perhaps that trope is so common that it applies it to everyone in science?
Seattle, WA 🇺🇸 English
Here's a frightening game:
Ask ChatGPT to write a biography of yourself ➡️ chat.openai.com
Then add up all the correct and incorrect facts ℹ️
Reply to this tweet w the percents ⬇️
Seattle, WA 🇺🇸 English
ChatGPT decided that I have a PhD (I don't), and that I went to UCLA (I didn't).
It also believes that I was involved in an early clinical trial for a Zika vaccine in 2014. (Close I guess?)
It's very wrong — but in interesting ways.
Seattle, WA 🇺🇸 English
If your online presence isn't huge, it might not work at all. And if you have a common name... good luck.
My ChatGPT biography is ostensibly about me, but 75% of the information is just not true.
Seattle, WA 🇺🇸 English