Jon

3.4K posts

Jon

Jon

@jon__p235

Kentucky Beigetreten Şubat 2021
466 Folgt250 Follower
Jon retweetet
Mr. Potato Head ⚡️
Mr. Potato Head ⚡️@MrPotatoHeadUSA·
The International Moth is a development sailing class known for decades of innovation and its ability to hydrofoil above the water.
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Anthropic
Anthropic@AnthropicAI·
The US government, citing national security authorities, has issued an export control directive to suspend all access to Fable 5 and Mythos 5 by any foreign national, whether inside or outside the United States, including foreign national Anthropic employees. The net effect of this order is that we must abruptly disable Fable 5 and Mythos 5 for all our customers to ensure compliance. Access to all other Claude models is not affected. We apologize for this disruption to our customers. We believe this is a misunderstanding and are working to restore access as soon as possible. Read our full statement: anthropic.com/news/fable-myt…
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DaVinci
DaVinci@BiancoDavinci·
Melted rugs by Faig Ahmed
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Science girl
Science girl@sciencegirl·
This ancient baobab in Madagascar stands like a living water tower, its enormous trunk swollen with thousands of liters of stored rainwater to survive the long, brutal dry season.
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Massimo
Massimo@Rainmaker1973·
This unique cafe in Vietnam lets diners sit amongst pools of koi carp as they eat their meals. The King Koi Coffee Garden in in Ho Chi Minh has tables and chairs submerged into a lake where 3,000 koi swim in and among customers.
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LeoDaVinciWave
LeoDaVinciWave@LeoDaVinciWave·
The Scalinata di Santa Lucia in Arzachena, Sardinia, features colorful stair murals by artist Giorgio Casu that change with new themes over time.
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Travis Akers 🇺🇸
Travis Akers 🇺🇸@travisakers·
Elon Musk: Trillionaire Jeff Bezos: Billionaire Public School Teachers: Can anyone help me get some pencils for my students?
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Science girl
Science girl@sciencegirl·
Thomas Deininger is a Rhode Island-based artist who creates complex sculptures from discarded objects and plastic waste to highlight issues of consumption, waste, and environmental pollution. Watch this 🤯 📹 tdeininger
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Jon
Jon@jon__p235·
@SquaredUpBuilds @JaredDHardin Add a binding arbitration clause to every contract. It won’t eliminate disputes, but it can save a lot of time, money, and headaches when they happen.
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Squared Up Builds
Squared Up Builds@SquaredUpBuilds·
Happened to me last year for about $7000. We agreed to two weeks of labor and he didn’t think we got enough done even though we signed contracts. Long story short I placed a lien went to Mediation mediator agreed I would be right in court, and he should pay me he did not pay me and now I’m going to file in the court. People are lame.
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Jared Hardin
Jared Hardin@JaredDHardin·
Bro.. I just had a guy email me saying he doesn't think he should have to pay the remaining balance because "he thinks I charged him too much".. He signed the quote, paid the deposit, I did the work, and now he does this. I'm about to learn how to place a lien on a property.
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Gene Smith
Gene Smith@GeneSmi96946389·
A friend of mine had her embryos screened by Herasight and they found one with an IQ score in the 99.99th percentile
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ArtNouveauDeco
ArtNouveauDeco@NouveauDeco·
Immeuble Félix Potin is an Art Nouveau building from 1904 in Paris designed by Paul Auscher (1866-1932).
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Jon
Jon@jon__p235·
Dario is basically saying we may be 1–3 years from civilization changing AI. Congress is operating on a timeline where it takes 3 years to rename a post office. One side thinks in weeks and months. The other thinks in election cycles. How exactly does that end well for all of us???
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Dario Amodei
Dario Amodei@DarioAmodei·
Today I'm publishing a new essay, Policy on the AI Exponential. AI is progressing extremely fast—much faster than the policy process was built to handle. The essay lays out where I think the technology is now, and the action needed to close the gap: darioamodei.com/post/policy-on…
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DaVinci
DaVinci@BiancoDavinci·
The world's most beautiful milk shop, founded in 1880 by the Pfund brothers in Dresden, Germany.
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J. R. VanHoose
J. R. VanHoose@JRVanHoose·
KENTUCKY FACT OF THE DAY: Historical records indicate that 64% of all American combat deaths in the War of 1812 were soldiers from Kentucky, most notably at the Battle of the River Raisin. The Bluegrass State lost more men in the war than all other states combined.
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LeoDaVinciWave
LeoDaVinciWave@LeoDaVinciWave·
Vintage Art Nouveau telephone lamps at Harrods in London.
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Afshine Emrani  MD FACC
Afshine Emrani MD FACC@afshineemrani·
I'm a cardiologist. I've held dying hearts in my hands in the cath lab at 3 AM. And I need to tell you something that changes everything about how we prevent heart attacks. For decades, the entire field was built on one target: lower LDL cholesterol. Statins save lives — that's settled science. But too many of my patients did everything right — took their statins, hit their numbers, lived clean — and still ended up on my table with a ruptured artery. We were treating the smoke while the fire kept burning. The fire is inflammation. And the evidence is now overwhelming. The CANTOS trial proved it first — lowering inflammation independent of cholesterol reduced cardiac events. But the newer data is what keeps me up at night. AI-enhanced CT angiography can now detect inflamed arteries by measuring changes in the fat surrounding your coronary vessels — the perivascular fat attenuation index. Higher inflammation in the fat around even one artery independently predicts cardiac death. When multiple arteries show inflammation, the risk multiplies dramatically — even in patients whose cholesterol looks perfect. This isn't theoretical. This is measurable. Right now. On a scan you can get this month. Low-dose colchicine — a drug that's been around for centuries for gout — is now FDA-approved specifically for reducing cardiovascular events. It works by quieting the inflammatory cascade that destabilizes the plaque sitting in your arteries. A pill that costs pennies is saving lives the statins couldn't reach. And the next wave is already in Phase 3 trials. Ziltivekimab — an IL-6 inhibitor — targets the central inflammatory pathway driving atherosclerosis. Phase 2 data showed a 90% reduction in hsCRP. The ZEUS cardiovascular outcomes trial is enrolling now, with results expected late 2026 into 2027. If positive, anti-inflammatory therapy will become standard in managing heart disease alongside lipid-lowering. The era of inflammation-targeted cardiology is arriving. But it goes deeper than drugs. AI is now predicting heart failure and cardiac events 5+ years before symptoms — integrating CT imaging, electronic health records, and genetic data with accuracy that jumps far beyond traditional risk calculators. And polygenic risk scores — a simple genetic test that flags inherited cardiovascular risk — are now formally recognized as a risk-enhancing factor in the 2026 ACC/AHA guidelines. A single blood draw can reveal risk that's been silently building since birth. Decades before the first chest pain. Here's what this means for you right now — today: Ask your doctor for a high-sensitivity CRP test. It's cheap, routine, and measures the systemic inflammation that standard cholesterol panels completely miss. You can have perfect LDL and inflamed arteries that are quietly preparing to rupture. If your hsCRP is elevated, discuss low-dose colchicine with your physician. It's FDA-approved for exactly this. Push for a coronary CT angiography with AI plaque and inflammation analysis if you have risk factors. This isn't the stress test your parents got. This is 3D visualization of your actual arteries — with AI quantifying not just how much plaque you have, but what kind it is and whether the surrounding tissue is inflamed. Consider polygenic risk score testing — especially with a family history of early heart disease. It's now guideline-supported. And the foundation that never changes: move daily, eat real food, sleep 7-9 hours, manage stress, and know your numbers — ApoB, Lp(a), hsCRP, fasting insulin. I left Iran as a child with nothing. I rebuilt everything in a country that gave me the freedom to become a physician. I've spent twenty years watching patients get second chances. The ones who haunt me aren't the ones who died on my table. They're the ones who survived but never acted on what the science was telling them — years before the event that didn't have to happen. You can have perfect cholesterol and still have a heart attack. Inflammation plus genetics can drive plaque rupture in arteries that look "fine" on a standard panel. The myth that normal cholesterol means you're safe has cost more lives than I can count. We now have the tools to detect the fire — not just the smoke. AI to see it. Genetics to predict it. Drugs to quiet it. And the ancient basics — movement, real food, sleep, purpose — to prevent it from starting. Prevention is the new cure. And the science to make it real is no longer coming. It's here.
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LeoDaVinciWave
LeoDaVinciWave@LeoDaVinciWave·
The facade of the Glassmaker’s House in Brussels, Belgium, designed by architect Ernest Delune in 1902.
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miia
miia@miiagarro·
the world contains protons, neutrons, electrons and fucking morons
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