Todd Lab @UM

It took a near-collapse of our research infrastructure and a constitutional crisis to make it happen, but we are moving our former Twitter activities to Bluesky. Looking forward to a happier scientific discussion in this new space: bsky.app/profile/realto…

🗣📢REGISTRATION IS NOW OPEN! 10th Annual RNA Symposium, March 6-7, 2026! 🧬RNA Frontiers: From Mechanisms to Medicine. Celebrate a decade of innovative RNA science and medicine @UMich. For more information, visit rna.umich.edu/events-navigat… @umichmedicine @realToddLab #UMichRNA

If the PNAS version of the article is behind a paywall for you, the preprint is here: biorxiv.org/content/10.110…

Ever wonder how intronic repeats in C9orf72 get translated into toxic proteins in ALS? We found that transcription initiates within the intron to generate novel endogenous mRNA templates for RAN translation in patient neurons and mouse models. 1/5 pnas.org/doi/10.1073/pn…

@sh4nnonmiller @KatelynMGreen @BoyleLab @BarmadaLab @NINDSfunding @VAResearch actually that should be @alanboyle.bsky.social

This project was led by @sh4nnonmiller and @KatelynMGreen with help from @BoyleLab and @BarmadaLab and everyone in @realToddLab. Thanks to @NINDSfunding and @VAResearch for support!

Bummed I missed it this year!

You deserve better. We all do.

Half of children died. A thread. 🧵

Excited to organize this CSHL Asia meeting with @pengjinATL on Repeat Expansion Disorders. Hope you all can join us!

Cold Spring Harbor Asia Meeting - Short Tandem Repeats in Gene Regulation and Disease @CSHANews csh-asia.org/?content/2754

Stand Up For Science DC #StandUpForScience Science will not be silenced

Thank you NIH funded basic science

A two-and-a-half-year-old girl shows no signs of a rare genetic disorder, after becoming the first person to be treated for the motor-neuron condition while in the womb. go.nature.com/4i9BpEx

Sharing a symposium on #RareDiseaseDay that will be held at the Kellogg Eye Center Auditorium. RSVP using this link: forms.gle/K5siWBAtgrUU2P…

NEW: The Trump administration is exploiting a loophole to keep funding frozen at the NIH - a move that some legal experts say is illegal. Federal Register notices are blocked so no grant-review sessions can be scheduled. All the gritty details in @Nature nature.com/articles/d4158…

Last night my brilliant friend with 20 years of expertise in Neuroscience including a decade at NIDA was fired because she was recently promoted for her outstanding performance and it triggered the probation period. This is not making NIH more efficient, this is not making us healthier, this is not punishing the people who misled the public, this is destroying America’s talent. Her work is instrumental for testing whether new medications to fight addiction are safe and efficacious before they are tested in humans. now that research is at risk. She was the backbone of the lab the most senior person. So much knowledge, talent, know how, wasted, so much science destroyed for the wrong reason. Sigh…