Stuart MacGregor

#AAHMSFellow @stuartmacgreg of @QIMRB_Institute is a world authority on the conduct and analysis of genetic association studies. He has led studies which have mapped hundreds of genes for diseases ranging from skin cancer to eye disease.

probably Theseus, but it’s changed over time

A 5-year observational study of ~12,000 individuals with obesity taking GLP-1 drugs (without diabetes) with propensity matched controls A significant reduction of all-cause mortality (HR 0.23, 95% CI 0.15, 0.34) …ubs.pericles-prod.literatumonline.com/doi/10.1111/do…

Two impressive @Nature papers on the genomics of colon cancer, linking with outcomes, identify new mutations, likely role of diet and strengthen the case for sequencing to be used in medical practice nature.com/articles/s4158… nature.com/articles/s4158…

Kind of a big deal: GPT-4 simulates people well enough to replicate social science experiments with high accuracy Note this is done by having the AI prompted to respond to survey questions as a person given random demographic characteristics & surveying thousands of "AI people"

Cigarette sales and lung cancer deaths are the same curve, shifted 25 years.

Today we opened a web portal for our 210,000 biobank participants! We currently return results on: - Genetic & cumulative risk for cardiovascular disease and type 2 diabetes; - Pharmacogenetics reports; - Ancestry information; - Fun facts, e.g.caffeine metabolism & % Neanderthal.

Sobering reading for any one who has put countless hours into grant writing (or been on a review panel)

@drjosephpowell @nhmrc Congratulations Joseph. Very well deserved.

I'm very grateful to receive an @nhmrc Investigator Grant. This really reflects the terrific work of my lab members and collaborators. Thank you also to the reviewers for their time and valuable comments. And finally.... phew!! nhmrc.gov.au/sites/default/…

After 20 years and 42 days, Illumina's patent covering DNA microarray normalization, clustering, and genotyping, together known as Illumina GenCall, filed on March 24th 2004, has expired patentcenter.uspto.gov/applications/1… 1/8

Congratulations to Professor @stuartmacgreg on being awarded a highly competitive national funding grants for crucial research into #glaucoma risk prediction. The @nhmrc’s Investigator Grants were announced on Thursday...

Mendelian Randomisation (MR) is going to hell in a handcart, with an exponential weekly increase of papers with Mendelian Randomisation in the title, most of them nonsense. 25th April 4.30pm online or in person @ucl I'll talk about what should be done forms.office.com/pages/response…

@ProfRScolyerMIA @JWilmott38 @inespiresilva @amenzies9 @MattCarlino @syd_health @CPC_usyd @SHPartners @SydneyResearch @SydneyCatalyst @PathologyRCPA That's wonderful news Richard!

Fantastic news!!!!!! Amazingly, my latest MRI brain scan shows no recurrence 10 months since my #glioblastoma presented with a seizure in #Poland. Median time to recurrence is 6 months. I’m extremely hopeful that the novel #neoadjuvant combination #immunotherapy I’ve had & the scientific changes we demonstrated in my tumour post versus pre immunotherapy are being translated into clinical benefit! I’d be thrilled & very proud if this novel approach makes a difference for me & future #brain #cancer patients. Thanks @ProfGLongMIA for devising & facilitating this superb approach & other members of multidisciplinary team including the @MelanomaAus team & other specialists @Dr_Brindha, Helen Wheeler, Michael Back & many others. Well done also to our @MelanomaAus translation research team including @HelenRizos! Special thanks for the ongoing support of my wife Katie, 3 kids Em, Matt & Luce, bro Mark, @subbie & many other family & friends! @SydneyLHD @Sydney_Uni @MelanomaAus @ausoftheyear

Very sadly, we have learned of the death of Professor Peter Armitage, CBE. Peter, who worked in a forerunner of the Unit 1947-1961, was a pioneer in developing statistical methodology for medical research. Our annual Armitage Lecture began in 2003 to honour this special man.

We will add an asterisk symbol next to our names with the caption 'These authors contributed equally to this work'

@JaneMTiller Done! Thanks for advocating for this.

Forgot to write to the consultation on genetic testing & life insurance? It's not too late! Sit down tonight & spend 5 minutes. There are tips at the link below - you don't have to spend hours puzzling about what to say. Short & sweet is fine, but this is your last chance 💜🧬

This means Australians are being left behind. Our future prosperity, health, environment, and security depends on it. Australia being ‘left behind’ as federal research and development funding sinks to 30-year low theguardian.com/business/2024/…

If you're aged 50-65 years and have a family history of glaucoma (affected parent and/or sibling) but no personal history of the disease, we invite you to be part of our study. Apply here: qimrberghofer.edu.au/genetics-of-gl…

ICYM our brilliant 2023: A stunning year of medical breakthroughs for Queenslanders @QIMRBerghofer couriermail.com.au/news/queenslan… via @couriermail @JSinnerton