Bergmeier Lab

She will investigate the regulation platelet procoagulant response by Rap1 and Rho family small GTPases & will utilize novel in vivo imaging techniques, proteomics & functional platelet assays to establish the in vivo significance of Rap1 in platelet procoagulant response...3/3

Abigail Ballard PhD candidate in Wolfgang Bergmeier’s lab @scheibech was awarded a Ruth L. Kirschstein NRSA Predoctoral Fellowship (F31) from @nih_nhlbi . @UNC_SOM @UNC_GradSchool @UNCResearch & UNC Blood Research Center 1/3 go.unc.edu/Fp3f9

Jean Marie N. Mwiza has the cover article in the May 2022 issue of Blood! Congrats: Robert H. Lee, David S. Paul, Lori A. Holle, Brian C. Cooley, Bernhard Nieswandt, Wyatt J. Schug, Tomohiro Kawano, Nigel Mackman, @Jeanmariesabato @scheibech @aswolberg go.unc.edu/p6G5C

Both G protein–coupled and immunoreceptor tyrosine-based activation motif receptors mediate venous thrombosis in mice loom.ly/o9yKYL8

This week we are featuring Abigail Ballard! 🔬 Abby is a third-year PhD candidate in the Bergmeier lab at UNC studying platelets. Abby is in the Biochemistry and Biophysics department and is on our executive team! 🎉 Checkout her video to learn more! @UNC_BCBP @abigailrballard

UNC Graduate Student Jean Marie Mwiza in Wolfgang Bergmeier & Alisa Wolberg labs, Published Platelet research in the Journal Blood!@Jeanmariesabato @JeanMar88658122 @RobertHLee8 @scheibech @aswolberg @ASH_hematology @UNC_SOM @uncpbts @UNCResearch go.unc.edu/d5T8A 1/2

Congratulations to @Jeanmariesabato for receiving an American Society of Hematology Abstract Achievement Award for his abstract: The Small GTPase Rap1 in Platelets Is Critical for Arterial but Not Venous Thrombosis in Mice. Way to go JM!

Congratulations to Bobby Lee for receiving a 2-year grant from the Ehlers-Danlos Society for his project entitled, “Investigating Intrinsic Platelet Dysfunction in Ehlers-Danlos Syndrome”! med.unc.edu/bloodresearchc… med.unc.edu/biochem/news/r… #

Welcome to the lab Tristan Miller-Cottle! Our new Research Technician is ready to go and we're very happy to have him on the team!

Hi my name is Jean Marie, a fifth year PhD at UNC Chapel Hill. My work focuses on platelets in VTE. I'm passionate about cardiovascular research and advocating for a better tomorrow for everyone. #BlackInCardioRollCall #BlackInCardioWeek @UNC_BCBP @UNC_MHI @scheibech @aswolberg

Check our latest work! Two independent molecular approaches proved to be efficient in preventing the detrimental impact of a dominant-negative #VWF variant in vivo. First siRNA-based correction of #VWD in a mouse model @InsermU1176 @UniFerrara @JTHjournal pubmed.ncbi.nlm.nih.gov/33047469

Congrats to Jean Marie Mwiza for earning a Ruth L. Kirschstein Predoctoral Fellowship for his project, "Determining the Platelet Signaling Pathway(s) Critical in Venous Thrombosis Pathogenesis"!

@KateyRayner @atvbahajournals @scheibech Thanks for you question Katey! You're right...there was a obvious gap in the field that prevented us from studying in vivo human plt function. Specifically, we were interested in testing a Par1-receptor inhibitor (which is lacking on mouse platelets).

@atvbahajournals @BergmeierLab @scheibech Hey 👋 Bergmeier Lab! Wonderful work! I am curious what drove you to make this new mouse model, which is obviously much needed in the field. #AskTheATVBFirstAuthors

Welcome to #AskTheATVBFirstAuthors! First, we are featuring an exciting paper by @BergmeierLab @scheibech where they develop a new protocol for the adoptive transfer of human platelets into thrombocytopenic NOD/SCID mice. They are ready for your questions! ahajournals.org/doi/10.1161/AT…

@atvbahajournals @scheibech Ready and waiting.... @david_s_paul @scheibech

Looking forward to it! @David_S_Paul @scheibech @UNC_BCBP, @UNCResearch

New model for in vivo human platelet function testing helps bridge the gap between the bench and bedside. @BergmeierLab ow.ly/CGJL50AcObK

Congrats to one of our intrepid undergraduate researchers, Gracie Clark, for her contributions to the invention of the "Pipette Pal"! Read more here: launchchapelhill.com/blog/2020/6/18…

Congrats Dave Paul - fantastic work! Interesting paper for those of you who want to measure the true hemostatic function of human platelet products. ahajournals.org/doi/10.1161/AT…

We are seeking a postdoctoral research fellow to conduct in vivo and in vitro studies aimed at a better understanding of how the function of megakaryocytes and platelets is controlled by small GTPases. bergmeierlab.web.unc.edu @scheibech

Congratulations Bobby!